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We’re working on 1M Covid-19 testing capacity per day

billiontoone.com

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Re: We’re working on 1M Covid-19 testing capacity per day

#231
post #129
post #68

Earlier quoted context omitted.

The other bottleneck in WA is that the state's multimillion dollar, IBM-contracted data collection program can't keep up ingesting a few thousand records a day.

That's just for public data reporting, so doesn't stop people from actually doing tests.

Just realtime analysis, which is also very important.

Re: We’re working on 1M Covid-19 testing capacity per day

#232
post #102
post #68

Earlier quoted context omitted.

The other bottleneck in WA is that the state's multimillion dollar, IBM-contracted data collection program can't keep up ingesting a few thousand records a day.

Yes - this has been falling over for the past week.

Yep, starting March 28 (or sooner).

Re: We’re working on 1M Covid-19 testing capacity per day

#234

Earlier quoted context omitted.

That's where I've been getting data. We have a long way to go. https://docs.google.com/spreadsheets/d/1Y9_ZrMBhhVLg2xQHtBCc...

Why do you state that our testing capacity has been maxed out? My understanding is that factors like the availability of swabs and the availability of medical personnel to administer tests are a bigger bottleneck than qPCR machines.

I don't have any insight into the why. Only that the growth rate in tests per day has slowed to an almost stagnant level.

Re: We’re working on 1M Covid-19 testing capacity per day

#235
post #218
post #205

Earlier quoted context omitted.

In SA right now I believe everything is closed to a much greater extent than most other places. For example, restaurants are not allowed to even deliver food. Only ingredients for preparing meals at home can be delivered by grocery stores. No alcohol or tobacco. Aggressive policing of the rules.

> Only ingredients for preparing meals at home can be delivered by grocery stores. So they're also closed to in-person shopping?

No, that and pharmacies are the only shops that are open. You do get limited with the amount of people inside stores at any point in time. Also, you have to go to shops close to you, otherwise you'll get stopped by the police.

I think the comment was meant that if you are in the food business, the only option is to deliver ingredients. Some businesses that used to deliver vegetables to restaurants now deliver to houses instead.

But in-person shopping for food is allowed. I don't know what they will do in the medium term, because other services will have to start operating again.

Re: We’re working on 1M Covid-19 testing capacity per day

#236
post #54
post #43

Earlier quoted context omitted.

Wait, are you saying that you actually edited the text of someone's comment?

I do that occasionally when coaching YC startups with their HN launches ( https://news.ycombinator.com/launches ), which this is a variant of.

Wow...

Re: We’re working on 1M Covid-19 testing capacity per day

#237
post #2

I'm the co-founder and CTO at BillionToOne. I'm happy to answer any questions here. I've also posted a slightly more technical explanation of how the test works and why it can scale here: https://twitter.com/dtsao/status/1247642005510873088?s=21 Edit: Since our site seems to be overwhelmed at the moment, here's a recap: We’ve been working hard at BillionToOne on a new COVID-19 test that scales testing to everyone in…

It sounds like your work has amazing potential. How far have you come already, and what are your biggest challenges moving forwards? How many tests did you manage to process today?

Re: We’re working on 1M Covid-19 testing capacity per day

#239
post #71

Earlier quoted context omitted.

Hey, lowly Bio undergrad here, but how are you able to skip the RNA extraction step? I read the paper and you use the viral transport medium, but wouldn't you have to also purify RNA from that (or is it just much easier to extract RNA from that medium)? I also dived into the paper behind the "skip the RNA extraction step" methodology and it basically seems to swap out one RNA extraction kit for another (Qiagen RNeasy…

Thanks for the question! The goal of skipping RNA extraction is to decrease the amount of labor necessary for processing samples and also to eliminate a dependency on RNA extraction reagents that have recently become difficult to find. The FDA is very strict about the specific brand and model of kit you use, so showing that you can swap out one RNA kit for another is actually very useful because you will have allevia…

[deleted]

Re: We’re working on 1M Covid-19 testing capacity per day

#240
post #2

I'm the co-founder and CTO at BillionToOne. I'm happy to answer any questions here. I've also posted a slightly more technical explanation of how the test works and why it can scale here: https://twitter.com/dtsao/status/1247642005510873088?s=21 Edit: Since our site seems to be overwhelmed at the moment, here's a recap: We’ve been working hard at BillionToOne on a new COVID-19 test that scales testing to everyone in…

Your company is an inspiration and are doing a tremendous service to the world. I am a federal consultant and have a couple of companies in the medical space that I help find and write solicitations for. I'd love to help your company free of charge on anything and everything. I have alot of infrastructure built such as pricing tools, automated solicitation writing, a ton of outreach lists, etc. One such outreach list is of clinical labratory's nationwide with emails to executives and a ton of other information. I also work with a company that sells reagents and contract kits. I've also worked at Tesla on the Supply Chain, Capital Equipment team in the past and can help you procure any reagents or automated Sanger sequencers/ labs who have them. Additionally, I am fairly adept at SQL and Python (Pandas for data) and why I am a regular on Hacker News and how I found the comment. Let me know if there is anything I can do as I would be very proud to contribute anything to your mission.
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