I've been working remotely for 1 year and 3 months. The company I'm working for checks in once a week for about 20 minutes, other than that all communication is done through basecamp. I have to admit it's really hard for me and I just handed in my two weeks notice. I feel so isolated working from home and not being around other co-workers. I miss seing and interacting with other people. I'll be looking for a new job…
I worked in an office for the last several years, and finally just being around people all day every day just got unbearable.
I've been working from home for the last few months, and having 8 hours completely alone every weekday is wonderful.
And my coworkers skype and chat so I get low-grade social interaction.
So I guess that's the answer: for some people being around others is more stressful than being alone.