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Ozempic shows anti-aging effects in trial

trial.medpath.com

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Re: Ozempic shows anti-aging effects in trial

#221

Post by throwawaylaptop »

tjader wrote: post #219
throwawaylaptop wrote: post #218

Earlier quoted context omitted.

Well then luckily that shows you hopefully how bad studies are. Because I assume that you agree that eating 100 calories of Pop-Tarts per hour for 18 hours for 30 days, would give you a different result than eating 3 days worth of Pop-Tarts in a few hours once every 3 days for a month. To not understand that would mean that while believing some studies, you completely ignore all the studies that have been done on ins…

> Because I assume that you agree that eating 100 calories of Pop-Tarts per hour for 18 hours for 30 days, would give you a different result than eating 3 days worth of Pop-Tarts in a few hours once every 3 days for a month. I agree that you would feel very differently in those situations and it's likely you wouldn't spend the same amount of energy unless you really make an effort to do it. I don't agree that if you…

Two weird assumptions here...1, that massive amounts of constant blood sugar/insulin don't affect metabolism.

2, that in the face of crazy long term insulin/hormone disruption, people will continue to be just as active as if they had a sane diet of mostly meat and vegetables.

I'm starting to see why everyone is so unhealthy.

Re: Ozempic shows anti-aging effects in trial

#222

Post by Aurornis »

XorNot wrote: post #160
Aurornis wrote: post #118

Earlier quoted context omitted.

> And also the idea that it is "easy" to lose weight is completely out of touch. If it was there wouldn't be millions of people trying hard, spending money on trying and failing for decades, and entire businesses addressing that. This is a touchy topic, but I would like to point out that you're missing the obvious confirmation bias that comes with this observation. There are many people who modulate their weight by c…

With 40% of US adults overweight, that is a substantial plurality though. It's not confirmation bias when it's more then 1 in every 3 people.

> It's not confirmation bias when it's more then 1 in every 3 people

If you construct your argument to exclude the 2 out of 3 people who are not overweight and then point out that the remaining 1/3 is overweight, that's the definition of confirmation bias.

It's also a disingenuous argument because not all of those 40% are actively trying and failing to modulate their weight in any way. Most people just don't care.

Re: Ozempic shows anti-aging effects in trial

#224

Post by throwawaylaptop »

op00to wrote: post #202
throwawaylaptop wrote: post #185

Earlier quoted context omitted.

[flagged]

[flagged]

I've been on here for 10+ years I think at this point. New throwaway, named throwaway to not even lie, every few months. I tweet with Paul G every now and then positively, because I'm nicer on there. But sorry you dont think I provide value.

Re: Ozempic shows anti-aging effects in trial

#225

Post by Aurornis »

nxobject wrote: post #132
Aurornis wrote: post #111

Earlier quoted context omitted.

> Many people (will only speak to America), view being fat as a literal moral failing. Gluttony or overeating are not the sin, but being fat. I feel like I've seen and heard more of the opposite: The trend is to avoiding anything that might make someone feel blame for arriving in their situation. With obesity the trend is to blame some combination of "our food supply", trending science topics like microplastics or th…

> I feel like I've seen and heard more of the opposite: The trend is to avoiding anything that might make someone feel blame for arriving in their situation. > I've heard countless people explain to me that dieting doesn't work for them. I think you're being a tad reductive – "dieting right now doesn't work for me for reasons I can't control" and "reducing calorie intake will help me reduce weight" aren't necessary c…

> and _then_ blame themselves.

I was responding to a comment about Americans blaming others, not dieters blaming themselves.

The concept of "blame" isn't really helpful anyway. The problem I frequently see is that blame becomes something to be avoided, which turns into a game of externalizing the source of the problem, which makes people think the problem is out of their hands.

A similar pattern happens in addiction and addiction counseling, where well-meaning friends and family try to soften the blow by telling the person that the addiction was not their fault, it was the result of their circumstances or bad influences. Addiction counselors have to undo this thinking and find a way to gently get the person to take some ownership of their role in arriving at the problem, which is the first step to having some control over correcting it.

For nutrition, when people convince themselves that they have a hidden metabolic disadvantage that makes caloric restriction not work for them, they're more likely to give up than anything.

Re: Ozempic shows anti-aging effects in trial

#226

Post by throwawaylaptop »

stavros wrote: post #191
throwawaylaptop wrote: post #142

Earlier quoted context omitted.

I helped my dad lose 50 lbs by finally, after 10 years, getting him to give up bread, sugar, potatoes. It took buying him 2 months of a bluetooth glucose monitor. Once he saw what certain foods do, he believed me finally. At 65 years old, healthier than I remember since he was 40 and I was a teen. It doesn't require some weird injection.

I helped my dad lose 50 lbs by finally, after 10 years, getting him to give up bread, sugar, potatoes. It took buying him 2 months of Ozempic. Once he saw what stopping the cravings for certain foods can do, he believed me finally. At 65 years old, healthier than I remember since he was 40 and I was a teen. It doesn't require some weird bionic arm implant.

Lol, a glucose monitor is a bionic arm implant (for $200 total), and an injection disrupting your entire hormone system is what then?

Re: Ozempic shows anti-aging effects in trial

#227

Post by Aurornis »

davorak wrote: post #175
Aurornis wrote: post #111

Earlier quoted context omitted.

> Many people (will only speak to America), view being fat as a literal moral failing. Gluttony or overeating are not the sin, but being fat. I feel like I've seen and heard more of the opposite: The trend is to avoiding anything that might make someone feel blame for arriving in their situation. With obesity the trend is to blame some combination of "our food supply", trending science topics like microplastics or th…

> Even Eliezer Yudkowsky, a figurehead of the "rationalist" movement, has written about "metabolic disprivilege" and claimed that his genetics do not allow him to lose weight through dieting. This thinking runs deep. I thought EY's point was different. Am I misremembering? I thought it was about not being able to do mental work productively when dieting enough to loose weight(maybe maintain a low weight too, though I…

It's a long story. His description of "dieting" was extreme calorie restriction. He was eating something like 800 calories per day (don't quote me on the exact number) and then was complaining that he didn't feel well when doing that (to the surprise of absolutely nobody).

Then it turned into a false dichotomy between the 800 calorie severe calorie restriction or no dieting at all. Then he just started declaring he'd delete any comments that suggested dieting.

Re: Ozempic shows anti-aging effects in trial

#228

Post by Aurornis »

throwawaylaptop wrote: post #146
noah_buddy wrote: post #20

Earlier quoted context omitted.

Many people (will only speak to America), view being fat as a literal moral failing. Gluttony or overeating are not the sin, but being fat. (From that perspective:)a miracle cure that allows someone to stop being fat is like an indulgence (in the Roman Catholic sense). It’s a cheat, a shortcut that allows the unworthy to reach a state they do not deserve. My opinion is to wait long enough to validate there are no lon…

You can be gluttonous and still thin. I eat 2 lbs of ground beef a day, with tons of cheese on it. For breakfast I have 6-8 eggs, with cheese. I have my morning coffee with heavy whipping cream. For desert, I whip up some of the heaving whipping cream and have it with frozen berries thawed out. It drives gfs nuts but they're too anti fat to try it.

Eggs have about 60 calories each.

Cooking 2lbs of ground beef could yield a little over 1500 calories (Source https://www.uhhospitals.org/health-information/health-and-we... )

A tablespoon of heavy whipping cream is 50 calories.

There's nothing incompatible with what you wrote and a 2500 calorie diet.

This confuses a lot of people who associate certain foods with becoming fat, or think that eating fat makes you fat.

It's entirely possible to eat what you described and maintain a neutral weight.

There isn’t any real secret to this: This combination of foods leads to you eating a calorically neutral amount every day.

That’s a horrifying amount of saturated fat per day, though. This is an extreme risk for heart disease.

Re: Ozempic shows anti-aging effects in trial

#229

Post by hackeraccount »

HarHarVeryFunny wrote: post #7
riku_iki wrote: post #5

what would be reversing biological age from regular running and eating chicken breast + veggies with olive oil.

You can tell if that regime reverses aging when you instead start wanting to eat chicken nuggets and mac & cheese.

Nice.

Re: Ozempic shows anti-aging effects in trial

#230

Post by throwawaylaptop »

Aurornis wrote: post #228
throwawaylaptop wrote: post #146

Earlier quoted context omitted.

You can be gluttonous and still thin. I eat 2 lbs of ground beef a day, with tons of cheese on it. For breakfast I have 6-8 eggs, with cheese. I have my morning coffee with heavy whipping cream. For desert, I whip up some of the heaving whipping cream and have it with frozen berries thawed out. It drives gfs nuts but they're too anti fat to try it.

Eggs have about 60 calories each. Cooking 2lbs of ground beef could yield a little over 1500 calories (Source https://www.uhhospitals.org/health-information/health-and-we... ) A tablespoon of heavy whipping cream is 50 calories. There's nothing incompatible with what you wrote and a 2500 calorie diet. This confuses a lot of people who associate certain foods with becoming fat, or think that eating fat makes you fat.…

I agree of course. Only note is when I say coffee with heavy cream, I mean like half a cup of it into espresso to make a cream latte.

And over a cup whipped for desert.

But I'm also 6'4".

When I ate the standard American diet I was about 40 lbs heavier than I am now.

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