GLP-1 drugs: An economic disruptor? (2024)
221–230 of 553 posts
Re: GLP-1 drugs: An economic disruptor? (2024)
#222I started Tirzepatide 3-4 weeks ago. (Mostly as an experiment to understand the hype around GLP's... I don't have diabetes and only very slightly overweight at 20% body fat). Even at the lowest 2.5mg starter dose which you're only allowed to stay on for 1 month: - Extreme appetite suppression to the point where I've started calorie counting specifically to make sure that I'm eating enough. It's incredibly easy to for…
Re: GLP-1 drugs: An economic disruptor? (2024)
#223I started Tirzepatide 3-4 weeks ago. (Mostly as an experiment to understand the hype around GLP's... I don't have diabetes and only very slightly overweight at 20% body fat). Even at the lowest 2.5mg starter dose which you're only allowed to stay on for 1 month: - Extreme appetite suppression to the point where I've started calorie counting specifically to make sure that I'm eating enough. It's incredibly easy to for…
Re: GLP-1 drugs: An economic disruptor? (2024)
#224Earlier quoted context omitted.
[flagged]
Can you please not harangue another user like this, regardless of how much you feel they should or shouldn't be spending? https://news.ycombinator.com/newsguidelines.html
Re: GLP-1 drugs: An economic disruptor? (2024)
#225I started Tirzepatide 3-4 weeks ago. (Mostly as an experiment to understand the hype around GLP's... I don't have diabetes and only very slightly overweight at 20% body fat). Even at the lowest 2.5mg starter dose which you're only allowed to stay on for 1 month: - Extreme appetite suppression to the point where I've started calorie counting specifically to make sure that I'm eating enough. It's incredibly easy to for…
I've never had any psychological difficulty with losing weight. I don't care if I'm hungry.
But what happens when I eat less and lose weight is that I have trouble concentrating. The glucose my brain needs just isn't there. And if I do physical activity, forget about it -- my blood sugar is going to my muscles and I'm unproductive for hours afterwards as I just can't think. Also, if I go to the gym, my muscles take a week to recover instead of a couple of days, because they're just not getting the glucose they need to repair themselves.
I don't hear any of these complaints from GLP users though, which baffles me. Not eating enough affects us in lots of ways besides just being hungry. How has it been for you?
Re: GLP-1 drugs: An economic disruptor? (2024)
#226I started Tirzepatide 3-4 weeks ago. (Mostly as an experiment to understand the hype around GLP's... I don't have diabetes and only very slightly overweight at 20% body fat). Even at the lowest 2.5mg starter dose which you're only allowed to stay on for 1 month: - Extreme appetite suppression to the point where I've started calorie counting specifically to make sure that I'm eating enough. It's incredibly easy to for…
Re: GLP-1 drugs: An economic disruptor? (2024)
#227> alcohol spending fell 85% You've replaced one drug with another. Freud would be proud. > If you told someone in 1850 that air conditioning would reshape the global economy, they'd think you were crazy. This is incredibly misinformed. You've lived /with/ refrigeration and /without/ malaria for so long you have no Earthly idea how people in the opposite state lived their lives or saw the world around them. > We're di…
First, those in power rebased the diet of the masses to carbs. Consequence: an eternal epidemic of obesity, with the many known complications and illnesses as a result.
Then, they now try to remedy the problem by fucking with the human body's mechanisms. 100% guaranteed to cause terrible side effects, in the long term. It's always more complex than you think. The more coveted a "medication" for a societal problem is -- with the problem being the pigswill that is fed to the masses, and our absolutely terrible sedentary, movement-less lifestyle --, the more quickly it will be greenlit, and the greater damage it will do over time (those pesky "unknown unknowns"). The hubris of human industry is unlimited; here's one example:
https://en.wikipedia.org/wiki/Thomas_Midgley_Jr.#Leaded_gaso...
> On October 30, 1924, Midgley participated in a press conference to demonstrate the apparent safety of TEL, in which he poured TEL over his hands, placed a bottle of the chemical under his nose, and inhaled its vapor for sixty seconds, declaring that he could do this every day without succumbing to any problems.
Here's another:
https://en.wikipedia.org/wiki/Thalidomide_scandal
And the list goes on and on.
The obvious solution to the obesity epidemic is to dismantle the food industry and the 8 hours workday. Our eating and movement/exercise habits need to revert to not just pre-industrial, but pre-agricultural standards. Move a lot every week (at least on 4 days per week), welcome hunger back into our lives (hunger allows you to appreciate and enjoy simple food -- intermittent fasting is amazing), and eat food with high volume, but low calorie content, and/or with low glycemic index. Our stomach volume and our blood sugar control had evolved for those types of foodstuffs, yet due to said rebasing of the diet of the masses to carbs, we've been filling our bellies with artificial food that's hyper-charged on calories and that get absorbed immediately. That's the recipe for growing fat tissue.
Two wrongs don't make a right.
And a final comment:
> Analysts predict that by 2030, 30% of American adults will be on these medications
Why doesn't that prediction make everyone shit their pants, from fear? Do you really want to make all those people dependent on Big Pharma just so they can eat healthily? How more basic do our bodily needs get than that?
This meds are pure evil, they're a non-answer, they're a cop-out, they only transfer power from Big Food to Big Pharma.
This is the same shit as trying to "cure" society-wide depression and anxiety with drugs. It only suppresses (or replaces) the symptoms, without fixing the root cause. We're depressed because our engineered societies make our lives meaningless. The struggle for survival is real, and the universe is unfair and indifferent, so we certainly need society, to cope with that. Just not this way.
Re: GLP-1 drugs: An economic disruptor? (2024)
#228I started Tirzepatide 3-4 weeks ago. (Mostly as an experiment to understand the hype around GLP's... I don't have diabetes and only very slightly overweight at 20% body fat). Even at the lowest 2.5mg starter dose which you're only allowed to stay on for 1 month: - Extreme appetite suppression to the point where I've started calorie counting specifically to make sure that I'm eating enough. It's incredibly easy to for…
Re: GLP-1 drugs: An economic disruptor? (2024)
#229Big food corporations profit from ultra-processed foods that manipulate our natural systems. They design products that override satiety signals using calculated combinations of sugar, fat and salt to activate brain dopamine pathways. Their priority is profit growth, not consumer health. The consequences are significant health issues like obesity, diabetes and cardiovascular diseases. Healthcare systems struggle with…
I've just never bought this.
Does grandma manipulate you when she adds sugar to her cherry pie? Does she manipulate you when she adds salt to her mashed potatoes?
Foods -- "ultra-processed" or not -- don't "manipulate" you. They literally just either taste better or taste worse. Grandma, and her grandma before her, used sugar, fat, and salt, and thank goodness they did. These are normal ingredients. It's not like they're nicotine or heroin or something.
I mean, is a fig tree "manipulating" you when its figs ripen with sugar so they'll be eaten?
You're not being manipulated. You're just choosing to eat what you choose to eat based on what you like.
Re: GLP-1 drugs: An economic disruptor? (2024)
#230I started Tirzepatide 3-4 weeks ago. (Mostly as an experiment to understand the hype around GLP's... I don't have diabetes and only very slightly overweight at 20% body fat). Even at the lowest 2.5mg starter dose which you're only allowed to stay on for 1 month: - Extreme appetite suppression to the point where I've started calorie counting specifically to make sure that I'm eating enough. It's incredibly easy to for…
Be careful with all this. At one point I had gone 72 hours without eating or drinking anything and one beer by the pool had me on the floor. I keep hydrated these days but sometimes it’s an effort.