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Fentanyl vaccine tested in rats

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221–230 of 378 posts

Re: Fentanyl vaccine tested in rats

#221

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They’re adding Fentanyl to everything now. I have Burning Man-adjacent friends who take ecstasy once a year at festivals, and they’re terrified of getting a tainted dose. This affects many more people than just those addicted to opiates.

Test strips: https://dancesafe.org/ Or on amazon

Yep. I've seen bowls of those available for free at various events. Even if I'm not going to partake of stuff that would need those, I'm happy to see them passed around freely.

Re: Fentanyl vaccine tested in rats

#222

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Wait, what? Selling fentanyl as candy in every street corner shop is going to fix this?

I really don't undertand this binary thinking regarding drugs. It seems like there's at least a third option in there somewhere between "ban it all and everything related and lock people up for decades if they touch the stuff" and "put it in a Pez dispenser and give every elementary school student a 12 tab slider with lunch every day." We don't do that with alcohol or weed, I don't see why that's the first (and often…

I think the middle ground is, "medically supervised with informed consent" like we do with every other prescription medication. You wanna drop acid, take molly, pop an addy, or k-hole yourself, have a blast. Get a doctor to sign off that you know how it works, how to take it safely, what to do in an emergency or overdose situation, and that you don't have any complications with your health or other prescriptions.

It would at least be a safer and more honest policy about what the current state of recreational drug use is like in the US.

Re: Fentanyl vaccine tested in rats

#223
post #25
post #16

Watch this therapy disable the painkilling potential of every opioid in the body, including natural opioids.

The article actually discusses this: “The anti-fentanyl antibodies were specific to fentanyl and a fentanyl derivative and did not cross-react with other opioids, such as morphine. That means a vaccinated person would still be able to be treated for pain relief with other opioids,” said Haile.

What about twilight anesthesia? With my cardiac problem, I can't have general anesthetics, but I can have Fentanyl/Midazolam to sedate and numb up a bit. Saying "it's specific to fentanyl" doesn't help those for whom fentanyl is a life saving drug.

The reply above that the real issue is WHY Americans like fentanyl so much is on the money in my opinion.

Re: Fentanyl vaccine tested in rats

#224

The real issue here that people don't seem to want to face is the WHY. Why do so many people want to check out of life completely by abusing medicine? If we don't address that nothing is going to stop the drug abuse let alone the relapse and overdose. I'm not talking about "more 12 step" here but more of a Frommian psychoanalytic approach. You are broken because society is broken. You have the ability to change yours…

Humans were not evolved to resist these kinds of poisons. Nothing like this exists in nature. It’s an extremely potent chemical.

I'd say the opposite, nature creates all kinds of powerful attractants and poisons. There are plenty of things that will kill you at the micrograms dose. There are plenty of natural things that are horribly physically addictive.

Re: Fentanyl vaccine tested in rats

#225

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I think quite a lot of people ended up addicted to opioids against their will, by starting with being over prescribed highly addictive pain medication which then ended up making them addicted to opioids, and then later on ended up trying to feed that habit from the streets once the easy access to pain meds dried up. https://www.doj.nh.gov/news/2022/20220303-settlement-purdue-... Personally I've been avoiding oxyconti…

You're not wrong, but addiction is not a certain outcome. Most people who use a substance that can lead to addiction don't become addicted. The question is why can two people, for example, abuse alcohol for a period of their youth, but both don't become addicts? We need to look at this holistically. Overprescribing is a problem, but we shouldn't be needlessly afraid of these substances. Personally I've been prescribe…

> but addiction is not a certain outcome

Not certain but chances are very high with the new class of opioids.

Re: Fentanyl vaccine tested in rats

#226

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I guess I'm a bit torn on this. Even if we had an extremely fair and equitable society with growth I imagine there'd still be plenty of people who feel rejected or lonesome at times. Or just like the feeling that these drugs give them above normal drugs. I drink alcohol a couple times a week and do edibles once a month. I'm sure some would argue I'm not fulfilled but I think the easier explanation is that a lot of ti…

That sounds like a healthy amount of drugs. For people with self control like that, I think it would be healthy to trip once or twice a year and use stimulants (cocaine) for a party once a year. A heroin vacation to an opium den on occasion sounds wonderful. I certainly have used drugs socially (LSD in clubs or concerts can be fun), but also use them cannabis alone frequently.

This is the crazy thing about this whole issue. Some people can use drugs that are extremely harmful responsibly. It's a once-in-a-while excursion away from ordinary life. There's nothing wrong with having a scary drug, like heroin, a few times a year...except that for some people it leads to their entire life unraveling.

This idea that we're all the same and because drugs are physically addictive (i.e., sustained use leads to withdrawal of use ceases) means everyone would become addicts if they tried it is a D.A.R.E. style falsehood. It's true for some, but seemingly not most.

Even drugs/activities that don't seem physically very addictive, like pot and gambling, seem to have their addicts. I question what proportion of addiction is chemical and what is something deeper going on.

It's a pity though. I don't think I'm prone to addiction, but for the sake of my fellow humans and a functioning society I reluctantly accept that these things shouldn't be widely accessible. I've become much more of a prohibitionist as I've gotten older.

Re: Fentanyl vaccine tested in rats

#227

As someone who's not a drug addict or around people who use substances that might be tainted with it, I don't want this. If I'm in a car accident or a serious condition where I need immensely powerful pain-killers I sure as you know what want Fentanyl to work.

> you know what want Fentanyl to work [sic] Your concerns are addressed in the article you're commenting on

Not really. There are people for whom Fentanyl is the only real choice for use _during_ surgery. I'm one of them, and I don't want doctors mucking about inside my chest without ample pain relief.

Re: Fentanyl vaccine tested in rats

#228

Earlier quoted context omitted.

> The real issue here that people don't seem to want to face is the WHY. Why do so many people want to check out of life completely by abusing medicine People start using drugs for different reasons. It's not correct to say that everyone starts abusing drugs as a form of pure escapism. A lot of drug users start because they're simply seeking recreation and someone is nearby to make drugs available to them. It's as si…

There's absolutely some truth to that though. People do not fall into addiction at the same rate in all societies.

That's tricky though, as access to the drugs varies by society also.

Re: Fentanyl vaccine tested in rats

#229
post #191
post #152

Earlier quoted context omitted.

I think this highlights the importance of addressing the _why_ even more. Most people are terrified of accidental fentanyl exposure. Some people seek it out. Why is that?

> Some people seek it out. who's seeking it out? The article doesn't mention it, and the parent poster explicitly say that people are NOT seeking it out.

People that are already addicted may seek out the lowest cost opiate.

Re: Fentanyl vaccine tested in rats

#230

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I would suggest becoming actually educated before developing strong opinions. The drug is extremely useful and saves lives in a clinical setting; chances are it will save your life or someone you know and love. It's literally used _every hour_ around the clock in ERs. Nearly all problematic Fentanyl in the US is illegally imported and created by third parties overseas. It is not manufactured by those big bad US Pharm…

Yes, most of the fentanyl that's abused comes from illegal sources. However, like cocaine, methamphetamine and heroin, I put some of the responsibility on the people who created it and promoted its use in the first place. It's naive to think we could make "super heroin" and it would stay restricted to safe, controlled medical environments. I'm not convinced the good it does in certain cases outweighs the enormous har…

> "super heroin"

The whole problem with fentanyl is that it sucks, the high isn't very good, which makes it extremely dangerous if you think that it might be a good idea to try to take more. It's the opposite of super heroin. It's a garbage substitute for the actual fun stuff.

Yeah in its pure form it's a very strong opioid by weight, but that's of minimal relevance in practice.

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