Everyone is different, but personally I won’t buy a keyboard without separate Delete and Backspace keys, without Home/End/PgUp/PgDn/Insert keys, and without a dedicated Menu key [0], for any kind of serious work. I’d also imagine that one is prone to bump into the rotary knob if one is not fully conditioned to that keyboard. I applaud the T-shaped cursor block and the full-sized function keys, although it would be us…
Yep, everyone is different indeed. I've been using 30% keyboards (30, 33 or 36 keys) for 3+ years now. I used 40's for around 2 years before that. Now I can't stand any keyboard that requires my hands to move from the home position. Also being able to carry my keyboard to anywhere is a big plus for me.
But I do strongly prefer having 2-3 keys for each thumb to use, rather than just having 1 big spacebar.