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Antiplatelet and anticoagulant therapy resolves long covid in 24 patients

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Re: Antiplatelet and anticoagulant therapy resolves long covid in 24 patients

#221

Post by phnofive »

allturtles wrote: post #202
jonathan-adly wrote: post #165

Earlier quoted context omitted.

Using PPIs for a short duration is safe, using PPIs chronically is not safe and the risks have to be weighted very carefully. It's by far the most intervened on medications by clinical pharmacists (usually discontinuing for inappropriate use)

Maybe. Here's a skeptical view: "Despite a large number of studies, the overall quality of evidence for adverse effects of long-term use of PPIs is low to very low." [0] [0]: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6463334/

On the other hand, it has been linked to much higher rates of autoimmunities:

https://doi.org/10.3389/fimmu.2021.736036

Re: Antiplatelet and anticoagulant therapy resolves long covid in 24 patients

#222

Post by beagle3 »

ck2 wrote: post #212
beagle3 wrote: post #131

Earlier quoted context omitted.

Budedenide was shown to help significantly if given early. So does fluvoxamine. And sufficient vitamin D3 level seems to work well as a prophylactic. And yet there’s hardly any mention of them, let alone “everyday”.

If you read only positive analysis of those supplements/drugs, they always seem positive. Except they aren't doing what you think because you don't hear when they don't work. https://www.covid19treatmentguidelines.nih.gov/tables/fluvox... "No difference between arms in time to symptom resolution" "Fluvoxamine did not impact time to symptom resolution"

No, I read both positive and negative reviews when I can find them. I have not yet found negative reviews for budesenide (though some may exist). I did for fluv.

But I also found for remdesivir, which in the US and Israel is given like candy. My point being “hear about it everyday” is more related to politics and agenda than actual efficiency.

Re: Antiplatelet and anticoagulant therapy resolves long covid in 24 patients

#223

Post by sithadmin »

LinuxBender wrote: post #200
sithadmin wrote: post #99

Earlier quoted context omitted.

You're specifically using compounds like nattokinase to control blood pressure? Would be interested in hearing what your approach here is, or any literature you could share.

You're specifically using compounds like nattokinase to control blood pressure? Correct. Here [1] is one of the studies though there are quite a few on nih.gov that vary in results and P-value. In full disclosure I use much higher FU's than what is used in their test and have been using it for a long time building up to those levels so my risks are lower. I use this in combination with vascular de-calcification metho…

Interesting. Seems I have a new rabbit hole to investigate. Thanks for the response.

Re: Antiplatelet and anticoagulant therapy resolves long covid in 24 patients

#224

Post by [deleted] »

allturtles wrote: post #85
wantsanagent wrote: post #44

This is a big hammer. Please note this section: "A proton pump inhibitor (PPI) pantoprazole 40 mg/day was also prescribed for gastric protection. Such a regime must only be followed under strict and qualified medical guidance to obviate any dangers, especially haemorrhagic bleeding, and of the therapy as a whole." Induced hemophilia is no joke.

To be clear in case it's not clear to others, the PPI is not the 'regime' that creates the risk of bleeding, it's the thing you take to provide some stomach protection against the damage/potential damage from the other drugs.

[deleted]

Re: Antiplatelet and anticoagulant therapy resolves long covid in 24 patients

#225

Post by dolni »

yosame wrote: post #219
swader999 wrote: post #155

Earlier quoted context omitted.

I read all that a while back. It is good and about all you can get out of it is to conclude that ivermectin needs more study. Unfortunately its off patent and won't get much $$$ thrown at it. Its getting hard to ignore the growing mass of people that have just said, hey, this is obviously safe and I'll just try it. And holy sh-t it worked! (that's my story...).

If ivermectin actually worked, pharma companies would just make a new version with a slightly different structure and patent/sell that formula instead.

No they wouldn't, because it would be trivially outcompeted by current ivermectin which can be had for very, very cheaply.

Re: Antiplatelet and anticoagulant therapy resolves long covid in 24 patients

#226

Post by swader999 »

mikeyouse wrote: post #191
swader999 wrote: post #188

Earlier quoted context omitted.

I didn't suggest anyone use IncellDX or covid long haulers.com. Just because Bruce Patterson had his name associated with the flccc doesn't prove anything about it's viability. Keep trying.

If the fact that fraudulent grifters developed the treatment protocol you're advocating for, I'm not sure where to go from there. (Not just Patterson, but Yogendra too -- it's not just "his name associated" with flccc -- he and yogendera are two of the primary authors of the protocol!) And if I understand your timeline right --- you think a single dose of the vaccine gave you "long covid" symptoms? So you're going to…

What do you think of this pre print from December? https://www.researchgate.net/publication/357313430_Ivermecti...

Re: Antiplatelet and anticoagulant therapy resolves long covid in 24 patients

#227

Post by swayvil »

SketchySeaBeast wrote: post #206
swayvil wrote: post #199

Earlier quoted context omitted.

It's a pretty simple idea. I'm having doubts about this "confusion".

Fair enough. I think you're throwing a weird "disease" distinction and then moralizing angle into COVID which doesn't make any sense. We didn't just hit some sort of health critical mass for illness. COVID is its own beast and it's hurting a ton of people and implying it's people's fault for eating junk is bizarre.

The moral trip is all yours.

Re: Antiplatelet and anticoagulant therapy resolves long covid in 24 patients

#228

Post by mikeyouse »

swader999 wrote: post #226
mikeyouse wrote: post #191

Earlier quoted context omitted.

If the fact that fraudulent grifters developed the treatment protocol you're advocating for, I'm not sure where to go from there. (Not just Patterson, but Yogendra too -- it's not just "his name associated" with flccc -- he and yogendera are two of the primary authors of the protocol!) And if I understand your timeline right --- you think a single dose of the vaccine gave you "long covid" symptoms? So you're going to…

What do you think of this pre print from December? https://www.researchgate.net/publication/357313430_Ivermecti...

Haven't seen it - but via the acknowledgements, its lead scientists are being paid by a producer of Ivermectin and the program was instituted by the quack mayor who previously said rectal ozone administration could treat covid? My hopes aren't high.

Also, why did it take over a year to publish when the study ran from July-Dec 2020?

Started reading it now, and what? Why can't these people do real science?

> "Although study design, IRB approval, and data analysis occurred after completion of the voluntary prophylaxis program, all data were collected prospectively in real-time with mandated reporting to the registry of all events as they occurred during the citywide governmental COVID-19 prevention with ivermectin program"

https://www.nydailynews.com/coronavirus/ny-brazilian-mayor-t...

And what now -- the 2nd author is facing prison for massive ethics violations running a different covid study?

https://sei.saude.gov.br/sei/controlador_externo.php?acao=do...

The advocates for IVM are consistently some of the worst acting scientists on the planet. It's a real disservice to their stated goal that they're all so incompetent.

Re: Antiplatelet and anticoagulant therapy resolves long covid in 24 patients

#229

Post by allturtles »

phnofive wrote: post #221
allturtles wrote: post #202

Earlier quoted context omitted.

Maybe. Here's a skeptical view: "Despite a large number of studies, the overall quality of evidence for adverse effects of long-term use of PPIs is low to very low." [0] [0]: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6463334/

On the other hand, it has been linked to much higher rates of autoimmunities: https://doi.org/10.3389/fimmu.2021.736036

Many of those autoimmune disorders cause pain and inflammation. And many pain relievers and anti-inflammatories can cause damage to the stomach lining, which leads to a prescription for a PPI. I don't see any accounting for this possibility in the paper (that ADs cause PPIs, rather than vice versa).

Re: Antiplatelet and anticoagulant therapy resolves long covid in 24 patients

#230

Post by swader999 »

mikeyouse wrote: post #228
swader999 wrote: post #226

Earlier quoted context omitted.

What do you think of this pre print from December? https://www.researchgate.net/publication/357313430_Ivermecti...

Haven't seen it - but via the acknowledgements, its lead scientists are being paid by a producer of Ivermectin and the program was instituted by the quack mayor who previously said rectal ozone administration could treat covid? My hopes aren't high. Also, why did it take over a year to publish when the study ran from July-Dec 2020? Started reading it now, and what? Why can't these people do real science? > "Although…

Yeah that's brutal. Hard for me to reconcile it all given my personal experience with it.
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