221–230 of 401 posts
Can someone tell what is the equivalent dose of said calcifedol in regular D3? The article claims 0.532 mg have been used, which seems too large. From [1] I gather it's about 3x more potent, meaning we are talking about equivalent of 1.596mg of D3. Or, 10000% of RDA according to [2]. Is that right? [1]: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5460735/ [2]: https://ods.od.nih.gov/factsheets/VitaminD-HealthProfess…
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Wiki says that "Hydroxychloroquine is being studied to prevent and treat coronavirus disease 2019 (COVID‑19), but all clinical trials conducted during 2020 found it is ineffective and may cause dangerous side effects." https://en.wikipedia.org/wiki/Hydroxychloroquine
In the interest of free speech, here's a PDF with all the positive trials for HCQ: https://drive.google.com/file/d/1l6y3L_KGb1ilMW0FaP4VZsd7WvX...
But it's awfully irresponsible to pretend it's good for society to spread it.
Not everyone has the scientific knowledge necessary to understand p-values and what they mean for research like this. It's a lot to ask that everyone know the standard for publishing in medicine is a p-value expect 6 or 7 of them to be wrong.
It's much better to say "just because it's not illegal doesn't mean it's a good idea" and just not share such thoroughly bad information.
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And it's also summertime in the northern hemisphere, which means less vitamin-D deficiency. Coincidence?
Does it work the same way if you take oral vitamin D supplement? My skin is allergic to the sun (it hurts it bad) but I take daily vit D supplement.
However, for those who can get skin production it is probably better, as there may be other effects we don’t know of. Plus it self limits, whereas one can overdo supplements.
Surly now it's time to just start giving everyone some free vitamin D. Best case scenario: Less dead people. Worst case scenario: We all have healthier bones.
Vitamin D pills look to be 3-5¢ per day. Hardly seems like something I’d be supportive of creating a “free” supply chain for.
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I got one that is still in effect in Michigan- "Gyms are closed" (but bars and casinos are open) A virus that kills old and _obese_ people, and you are shutting down the gym? If anything I hope Coronavirus shifts politicians from business leaders to scientists.
Weight gain and loss is simple physics. If you want to reduce obesity, focus on the dietary input. Virtually nobody is active enough to burn the extreme number of excess calories consumed that leads to obesity and the maintenance of obesity.
Of course, someone who is obese will take a long time to get to a healthy weight if they are only losing a pound a week, but most people would have a hard time maintaining extremes of diet or exercise for a long period of time.
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Actually, even lighter skinned people can have lots of trouble generating sufficient vitamin D. My wife's family has the lightest skin possible but they all have vitamin D deficiency, if you have some kind of fatigue it is truly worth having your vitamin levels checked!
If they're that fair-skinned, is it possible that they're so careful about sunburn/cancer that they're getting less UV than most people?
In such cases, both conditions may required supplementation to correct.
So, fair to say that it can get complicated.
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Greater than 70% of African Americans are suspected to be Vit D deficient. Definitely worth getting tested if you can [1] especially if you live in the more northern latitudes. Doubly so during winter. [1] with the note that generally insurance is a real PITA with vitamin D testing. The trick usually is to list as a diagnosis code a previous history of low vitamin D. Yes it’s like a catch 22. You need prior testing s…
Using online labs it's super cheap to get it done yourself for less than $50/test. Not worth dealing with insurance BS and your doctor's likely nonsensical ravings about it, just do it and reimburse using your HSA if you have one.
Can someone tell what is the equivalent dose of said calcifedol in regular D3? The article claims 0.532 mg have been used, which seems too large. From [1] I gather it's about 3x more potent, meaning we are talking about equivalent of 1.596mg of D3. Or, 10000% of RDA according to [2]. Is that right? [1]: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5460735/ [2]: https://ods.od.nih.gov/factsheets/VitaminD-HealthProfess…
That’s about 60,000 IU? Not necessarily out of line for such interventions. In cases of deficiency doctors will often prescribe weekly doses of 50,000 I believe. Have also seen RCT on vitamin d and the flu where groups where given 250,000-500,000 IU’s in one shot. ....obviously nobody reading this should take anything near those doses without consulting a doctor and without knowing your current blood level, to be cle…
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Greater than 70% of African Americans are suspected to be Vit D deficient. Definitely worth getting tested if you can [1] especially if you live in the more northern latitudes. Doubly so during winter. [1] with the note that generally insurance is a real PITA with vitamin D testing. The trick usually is to list as a diagnosis code a previous history of low vitamin D. Yes it’s like a catch 22. You need prior testing s…
Using online labs it's super cheap to get it done yourself for less than $50/test. Not worth dealing with insurance BS and your doctor's likely nonsensical ravings about it, just do it and reimburse using your HSA if you have one.
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Is BMI a good indicator of obesity, though?
It’s actually pretty decent. It can make errors in the case of people with extreme muscle mass, or very low muscle mass for their size, or the very short, or the very tall. But for most people, if you’re over 25 bmi you probably could lose some weight. And at a population levels the errors above average out, even in a smaller group. People make a big deal over the exceptions to it while ignoring that it is broadly ac…