Earlier quoted context omitted.
It seems like if you replace WebAssembly with JavaScript in this comment it makes just as much sense. What is different about WebAssembly?
WebAssembly expands on the ability to do client-side stuff and makes it more accessible, so my fear is that it will make it more common. That's pretty much the entire difference. It's a difference of degree more than of kind. As I said, Javascript is making much of the web inaccessible to me, and WebAssembly, if it becomes popular, will only accelerate this loss.
Interactivity would be tricky, but static HTML is better than a blank page.
Edit: Found something very similar, but it targets legacy browsers using clickable image maps rather than privacy/security.