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Biomarker for chronic fatigue syndrome identified

med.stanford.edu

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Re: Biomarker for chronic fatigue syndrome identified

#221

Post by wavepruner »

specialist wrote: post #219
wavepruner wrote: post #129

Earlier quoted context omitted.

I found out last year the root cause of my CFS is life-long mercury toxicity (a well understood neurotoxin). I am responding very positively to treatment. I rarely talk about it because people get very upset when I tell them about the evidence of where the mercury came from.

Belatedly, FWIW, I guessed dental fillings. I had mine replaced ages ago. Haven't considered testing my mercury levels. Maybe I should. I had aplastic anemia as a kid, cause unknown, treated with a bone marrow transplant (before they had means to isolate stem cells).

Yea I've talked to hundreds of people who have had success with removing amalgam fillings. This was not my issue though.

I posted above about a test you can do. Feel free to write me at jbob286 (aat) gmail if you'd like more info. I can point you to a bunch of free resources that can help guide you through the process.

Re: Biomarker for chronic fatigue syndrome identified

#222

Post by wavepruner »

zemvpferreira wrote: post #146
wavepruner wrote: post #129

Earlier quoted context omitted.

I found out last year the root cause of my CFS is life-long mercury toxicity (a well understood neurotoxin). I am responding very positively to treatment. I rarely talk about it because people get very upset when I tell them about the evidence of where the mercury came from.

Do tell please, it would be educating for all of us. Hopefully you’ll find a less negative reception in this thread.

I have confirmed mercury toxicity through hair analysis, which is controversial and difficult to interpret. It is described in depth by an Princeton trained biochemist, Andrew Cutler, in his book, Hair Test Interpretation: Finding Hidden Toxicities.

This diagnosis has been confirmed by a dramatic improvement of symptoms upon treating specifically for mercury toxicity with low-dose chelation therapy.

My symptoms began when I was a baby. Before I ever ate any tuna. Before I was anywhere near a mercury thermometer. I've never had amalgam fillings. I've never been exposed to a mercury spill to my knowledge.

These are the facts that I am 100% certain on.

Re: Biomarker for chronic fatigue syndrome identified

#223

Post by wavepruner »

dennis_jeeves wrote: post #211
wavepruner wrote: post #129

Earlier quoted context omitted.

I found out last year the root cause of my CFS is life-long mercury toxicity (a well understood neurotoxin). I am responding very positively to treatment. I rarely talk about it because people get very upset when I tell them about the evidence of where the mercury came from.

wavepruner, what exactly are you using for chealation? Please mention things like where you are getting your treatment, and how many sessions did it take to show positive results.

I specifically follow Andrew Hall Cutler's frequent low-dose chelation protocol.

This is all done in 3-10 day rounds. I started with 1mg DMPS every 8 hours and saw rapid improvement of many symptoms within a few rounds. I worked my way up to 10mg DMPS and added ALA every 3 hours currently at 1mg.

I take many supplements which facilitate healing. It is unlikely that one would see rapid improvement without a proper supplement regimen.

I'm currently using 3mg DMSA only due to DMPS supply issues. I get many side-effects from DMSA so progress has slowed recently.

I've completed 37 rounds and have been chelating for just over a year. I know several people who are claiming near 100% remission of their symptoms after 2-6 years of chelation.

ALA is easy to obtain as it is regulated as a supplement. It is very dangerous to take in the doses normally sold if you are mercury toxic. DMPS/DMSA are prescription only, but is easy to get.

There is another product that I am going to try soon. They make dramatic marketing claims which makes me suspicious, but the science behind it is compelling once you dig past all the bullshit. It is called TRS annd is manufactured by Coseva.

Feel free to write me at jbob286 (aat) gmail if you have questions. I can point you to a bunch of free resources.

Re: Biomarker for chronic fatigue syndrome identified

#224

Post by whalabi »

jdietrich wrote: post #48
whalabi wrote: post #31

I'm just astonished by this. Millions of people (in the US alone!) suffer from this illness and I think everyone has wondered, or heard it wondered, if it's imaginary. For all these people to know there's something actually physically wrong with them is massive. It'll shift the thinking of everyone in the profession, of their families and friends and colleagues, and of themselves. It's a huge, huge breakthrough.

>Millions of people (in the US alone!) suffer from this illness and I think everyone has wondered, or heard it wondered, if it's imaginary. For all these people to know there's something actually physically wrong with them is massive. IMO the broader issue is the stigma against mental illness. The leading hypothesis remains that chronic fatigue syndrome is a mental illness. Both your comment and the linked article im…

You're right, I should've worded this more carefully.

What I meant is, there's people out there who dismiss this illness and I believe there's sufferers who have to fight to convince people that what they're going through is "real".

So for there to be physical evidence of something going on can only help everyone involved.

I didn't mean to suggest that without a clear physical marker that an illness isn't real, just that there are people who wrongly dismiss an illness without a physical marker.

Re: Biomarker for chronic fatigue syndrome identified

#225

Post by garfieldnate »

wavepruner wrote: post #129
GordonS wrote: post #55

Earlier quoted context omitted.

Keep in mind that CFS is a currently a diagnosis of exclusion - many people labelled with CFS may in fact have another, undiagnosed illness. For example, it's been found that a lot of CFS (and fibromyalgia) patients turn out to have small fiber neuropathy (damage to he nerve fibers that signal pain), and neurotoxins have been shown to cause general fatigue (I'm in mobile, so no references for now I'm afraid). The ski…

I found out last year the root cause of my CFS is life-long mercury toxicity (a well understood neurotoxin). I am responding very positively to treatment. I rarely talk about it because people get very upset when I tell them about the evidence of where the mercury came from.

I'd love to know what the source was! It might help my kids someday.

Re: Biomarker for chronic fatigue syndrome identified

#226

Post by snovv_crash »

kens wrote: post #137
Smaug123 wrote: post #2

Paper at https://www.pnas.org/content/pnas/early/2019/04/24/190127411... Pleasantly surprised to discover that it was legally available! The test appears to be ridiculously good. Perfect separation of 40 subjects into those who have been diagnosed with CFS and those who are known to be healthy, from blood samples. I want to see this replicated, by people who are not the original authors; but if this test is anything…

Thanks for the paper link. I read the paper and it's really a semiconductor sensor engineering paper, not a biology paper. The paper seems very preliminary; it shows that CFS and non-CFS sample have widely different impedances under osmotic stress, but the mechanism behind this is entirely hand-waving. If I'm reading the paper correctly, the samples were peripheral blood mononuclear cells (i.e. lots of different cell…

To me different impedances implies different electrolyte concentrations. That's my EE perspective, at least.

Re: Biomarker for chronic fatigue syndrome identified

#228

Post by rmtech »

sagebird wrote: post #52
whalabi wrote: post #31

I'm just astonished by this. Millions of people (in the US alone!) suffer from this illness and I think everyone has wondered, or heard it wondered, if it's imaginary. For all these people to know there's something actually physically wrong with them is massive. It'll shift the thinking of everyone in the profession, of their families and friends and colleagues, and of themselves. It's a huge, huge breakthrough.

I would like to see controls that make an attempt to differentiate psychogenic causes. IE if you paid 20 people who do not claim to have chronic fatigue syndrome but have depression to fake having chronic fatigue syndrome for two months- eg watch tv on a couch, then they were tested, I wonder if they would not have the biomarkers. Likewise, I would like to see how people who claim to have fibromyalgia would do on thi…

yeah, I think this should be repeated several times & with some better controls such as people who are bedridden for a different reason.
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