221–230 of 268 posts
> Yes. Most existing melatonin tablets are around ten to thirty times the correct dose. I couldn't find an explanation why they'd be sold at this dose from this article, which makes me suspicious of this. Am I missing something? What would be the motive for this?
> Yes. Most existing melatonin tablets are around ten to thirty times the correct dose. I couldn't find an explanation why they'd be sold at this dose from this article, which makes me suspicious of this. Am I missing something? What would be the motive for this?
In summary: "Commenters, including a patent lawyer, have filled in the rest of the story. Because melatonin is a natural hormone and not an invention, patents can only cover specific uses of it. The MIT patent covered the proper way to use it for sleep; a broader patent might not have been granted. The patent probably guided supplement companies, but expired about five years ago. It’s now legal to produce melatonin 0.3 mg pills, but people are so used to higher doses that few people do."
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My experience with Melatonin is similar to yours. I tried the 2.5 mg and the 5mg dosages. If anything they made my sleep even shallower in the sense, yeah I have my eyes closed but am fully aware of my thoughts and surroundings but am too lazy/tired to be physically active. It also gave me weird dreams (not that I mind). waking up was tiring because all night my mind was awake. I think its good for REM sleep but what…
Note that the article suggests the ideal dosage is 0.3 mg, and larger dosage might not have the desired effect.
I think it was .25 and .5 mg I tried -- half of the minimum dose that was available over the counter at that time. It was about 5 years ago, so don't remember too well.
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Another data point: I've been using it on and off for a year now and it's been a life saver. I can reliably get to sleep when I need to for the first time in my life As best I can tell it's not recommended for long term use because it hasn't been studied for that purpose and because there are prescription sleep aids that don't cause as much drowsiness I'm terrified of taking a prescription sleep aid because of all th…
The first generation antihistamines are strongly anticholinergic, so long term use might have cognative effects and may increase the chance of dementia later in life. They can also interact with a lot of other medication since they are much less specific than most drugs. I agree that they are still quite a bit better than GABA-A agonists. IMO, any sleep medication is best taken with breaks as frequently as possible,…
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Maybe focus on the content? Any disparity is just on this single sentence: "your appetite increases" (as opposed to "their" or "one's"). "Their" as used across the comment is not meant as the plural possessive. It's instead used as a gender-neutral pronoun (a common use) to avoid repeating "one's" or using "his/hers". It, in "your appetite increases and it's more likely to overeat" etc., refers to the situation/possi…
It was really distracting to read. The mix - and there was a they in there too - broke focus. Sorry.
Though "they" was used as a gender neutral pronoun -- not to change the subject from "one" to some group. E.g. as in: "if one drinks milk, their bones would benefit".
Melatonin is usually not (freely) sold in Europe while it can be easily bought in the US like vitamin pills or cod liver oil. Is there a recommendable online option with international delivery? (I don't consider the usual 'online pharmacies' recommendable. Even when buying Melatonin in a store in the US, there's still the issue that Melatonin manufacturers and sellers mostly control themselves …)
Melatonin is usually not (freely) sold in Europe while it can be easily bought in the US like vitamin pills or cod liver oil. Is there a recommendable online option with international delivery? (I don't consider the usual 'online pharmacies' recommendable. Even when buying Melatonin in a store in the US, there's still the issue that Melatonin manufacturers and sellers mostly control themselves …)
Couple anecdotal points: - Used to have to sleep problems - mainly just my mind racing with all the (stress of) things I had to do. The symptoms were trouble sleeping and/or waking in the middle of the night with instant thoughts of projects, task lists. - Melatonin didn't help me much. Maybe their effect was too subtle on me - maybe I was using the wrong dose as mentioned in the post. - Magnesium Glycinate pills bef…
I am sharing my experience because I know how awful sleep problems can be. I'm in my 30s and eat what many consider a very healthful diet - virtually no sugar, just veggies, high quality fats and proteins, and minimal fruit. I spend 7-9 hours in bed; yet wake up feeling exhausted every. single. day. I'd love to exercise, but I'm too continuously tired to get started. Melatonin, when taken via dissolving sublingual ta…
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It does, assuming you're getting enough vegetables; fruit is mostly sugar (high glycemic load which causes crashes, promotes diabetes, etc.), so not actually that good for you on the macronutrient level.
Uh not really. Most fruit is both low to medium GI and GL. Sugar in fruit is bound to fiber and bloodstream uptake is fairly slow. There is a negative correlation between RDA fruit consumption and diabetes.
If you eat the right meats, like liver, you get more vitamins and minerals then you would from fruit. So if you know what you are eating, it's fine to cut off fruit.
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fruit is not healthy for you, contrary to what you may have traditionally heard. you can get everything you need, vitamins and minerals wise, from vegetables, without the sugar that comes with fruits.
>fruit is not healthy for you https://academic.oup.com/ajcn/article/105/6/1462/4569801 Fruit consumption is inversely correlated with all-cause mortality as best we can tell. Probably something to be said about people who eat fruits being among the more health minded individuals as well and skewing results but it’s probably not “unhealthy” to eat fruits.
https://tylervigen.com/view_correlation?id=1703
People consuming fruit could be more healthy individuals in general, exercising and avoiding other types of food which might have more effect than consuming fruit. So be careful about drawing conclusions from correlations or epidemiological studies as you have to consider other possibilities.