Live data from Hacker News

The shingles vaccine may reduce the risk of dementia

economist.com

211–220 of 234 posts

Re: The shingles vaccine may reduce the risk of dementia

#211
post #71
post #67

Earlier quoted context omitted.

Well, now… I can tell you second hand that catching chicken pox as an adult is no picnic either.

No it is not. Ranked list of outcomes: 1. Not getting chickenpox at all. Highly desirable. 2. Getting chickenpox as a kid. 3. Getting chickenpox as an adult.

And last of all, DNSSEC.

Re: The shingles vaccine may reduce the risk of dementia

#212
post #199

Earlier quoted context omitted.

That sounds like nonsense. Most vaccines do not provide 100% immunity.

Not to the union, it's not. 'The plaintiffs alleged that the vaccines do not prevent someone from becoming infected with COVID-19 and characterized it as a treatment rather than a “traditional vaccine.”' https://calmatters.org/education/2024/06/covid-vaccine-manda...

You're aware that the article you posted is full of sovcit antivaxers?

The reason the case was dismissed was because the requirement was removed.

The case was reopened on appeal due to the rules being temporarily re-established.

Anything else is nonsense. This is spelled out in the article but wrapped with a bunch of whatifs and maybes and possiblies.

If your hypothesis was correct, then NOTHING is a vaccine.

Re: The shingles vaccine may reduce the risk of dementia

#213

Earlier quoted context omitted.

You’re taking a mouse study, and a study that says that people hospitalized with influenza are more likely to get dementia, and stating confidently that daycare workers are more likely to get dementia. That’s not “extrapolating some.” That’s just making stuff up. The study you cited is from Taiwan and merely states that “Physicians who were older, specialized in pediatrics and worked at local hospitals and clinics ha…

Wrong. Physicians (which includes pediatricians), who are in general less likely to get dementia, experience its signs at an older age in general due to protective effects of their high education. Among physicians, pediatricians seemed to have higher rates. The discussion is very low-yield though, since infections are already a minor point re: dementia, and none of the evidence is conclusive.

That’s not what that sentence says though.

>Among physicians, pediatricians seemed to have higher rates.

Not just pediatricians, but physicians that work at hospitals and clinics.

Which is nearly all of them.

I think what you’re dealing with is a low quality, low effort survey study from Taiwan, which was poorly written, so there is no point trying to figure out what they meant.

Re: The shingles vaccine may reduce the risk of dementia

#214
It appears my wife (Australian, 49) may be suffering from shingles. So this was an apt time for this article to appear.

She's seen her Dr and swabs are being processed. She's on antivirals and painkillers and has a nasty fever.

Now I am horrified about how awful it can be, after reading all the comments in here.

Re: The shingles vaccine may reduce the risk of dementia

#215
post #169

Earlier quoted context omitted.

This isn't common knowledge. This is something people (non-experts) are starting to infer, because we're seeing it with Long COVID - https://news.ycombinator.com/item?id=48877214 - but there's no reason to think this is something special about SARS-CoV-2 - it could just as well happen with all viral infections but we weren't looking. It reminds me that we didn't look at vaccine efficacy at the individual level until…

From a legal perspective, if the injection does not provide 100% immunity (when used as directed), then it cannot be called a vaccine, instead it is a therapeutic treatment. Because courts of law have recognized covid mRNA injections as therapeutic treatments, they cannot be mandated.

From a legal perspective, right and wrong are decided by a coin flip most of the time.

Re: The shingles vaccine may reduce the risk of dementia

#216

Unfortunately this is a spurious finding. See this presentation: https://youtu.be/qlTnnQytOJ0 The mechanism is that people with the shingles vaccine are less likely to visit the hospital (because they don't get shingles). Because they have fewer hospital visits they are less likely to receive an incidental diagnosis of dementia from a hospital.

Yes, though the above only addresses studies based on Zostavax. Shingrix might still offer some protection from dementia.

Re: The shingles vaccine may reduce the risk of dementia

#218

Earlier quoted context omitted.

Wrong. Physicians (which includes pediatricians), who are in general less likely to get dementia, experience its signs at an older age in general due to protective effects of their high education. Among physicians, pediatricians seemed to have higher rates. The discussion is very low-yield though, since infections are already a minor point re: dementia, and none of the evidence is conclusive.

That’s not what that sentence says though. >Among physicians, pediatricians seemed to have higher rates. Not just pediatricians, but physicians that work at hospitals and clinics. Which is nearly all of them. I think what you’re dealing with is a low quality, low effort survey study from Taiwan, which was poorly written, so there is no point trying to figure out what they meant.

It's not a strong study, and the demographic group was very particular, but it involved 30k physicians, which is something. I would have no problem conceding that I misread the study, but ChatGPT, which is obviously never wrong (joking of course), agreed with me: https://chatgpt.com/share/6a550f00-d174-83ea-b111-0369a8e4db...

Re: The shingles vaccine may reduce the risk of dementia

#219

I'm in my 40s with genetic predisposition for Alzheimer's. Been seriously considering the past year or two paying out of pocket for Shingrix. I think it would be ~$500 total for two doses. Sure, I could wait 7 or 8 years until I qualify via insurance, but is that really worth the risk for what is an easily absorbed cost to me? Especially when I have a friend in her late 30s who just went through a very rough bout of…

[deleted]

Re: The shingles vaccine may reduce the risk of dementia

#220

I'm in my 40s with genetic predisposition for Alzheimer's. Been seriously considering the past year or two paying out of pocket for Shingrix. I think it would be ~$500 total for two doses. Sure, I could wait 7 or 8 years until I qualify via insurance, but is that really worth the risk for what is an easily absorbed cost to me? Especially when I have a friend in her late 30s who just went through a very rough bout of…

This finding of shingles and dementia is likely due to “healthy vaccinee” bias as per the link someone else posted below: https://youtu.be/qlTnnQytOJ0?is=XJ0c5pWVV6Lg0IMs As per one of the slides around 7 minutes in, there are many vaccines that show a 20-40% reduction in mortality and dementia. The talk above basically says that “observational studies” may show great results, like the so-called protective action of…

Great video, thanks for the link.
Post reply on HN