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The question is absolutely legitimate in nature and neutral in tone.
Sure, but this isn't really an AMA thread [despite the offer to "answer any questions"]. This is about Sid's journey with (extremely advanced) cancer. Airing grievances about Gitlab is just out of place here, you gotta read the room.
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Sure, but this isn't really an AMA thread [despite the offer to "answer any questions"]. This is about Sid's journey with (extremely advanced) cancer. Airing grievances about Gitlab is just out of place here, you gotta read the room.
[flagged]
And get a grip - you are free to bring value to the world in your way if you're not happy to be an employee. Attacking others that have done nothing to harm you is entirely uncalled for, especially on a discussion about their own cancer. Please act like an adult.
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What an incredibly tone deaf question
The question is absolutely legitimate in nature and neutral in tone.
I cant understand how you could possibly think this question is not "tone deaf" unless you are genuinely autistic - not using it as an insult, genuinely curious - since such a question would be simply beyond the pale in polite society, given the context.
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> I think it's just one of the bugs in our genetic code that evolution didn't shake out. I say that not as a biologist or anyone who has done any work in the field. I'm just curious, do you know what the opinions about this stuff are from people that work in these fields, or that have dedicated their lives to it?
I work in this field. It’s more or less correct but kind of lacking in detail. Cancer is a property of all multicellular life. I think it’s best understood as the behavior of a dynamical system that loses the feedback control that keeps cell growth under control. Check out this paper from the Lander lab: https://elifesciences.org/articles/61026 It’s a bit jargon heavy but it’s a nice case study in how tumor growth is…
In practice, though, some species are way less prone to cancer than others. Orders of magnitude of a difference, even in mammals. Bats, notoriously. Or naked mole rats. On the other hand, mice get cancer fairly reliably.
Which means that there are biologically realistic way how to keep the danger at bay, and they seem to involve the immune system.
(slightly sarcastic) So we should give rich people diseases so they are incentivized to fund medical research? Sid seems like a decent person. I'm glad that he's able to push cancer research forward on his own. Hopefully his work will make things better for everyone else with bone cancer. Seems like that is well under way. (and I guess I should recognize that he funded a cancer treatment company years before he knew…
Why can’t we just ask our governments to spend more on research? Want some rich person to donate $100 billion on cancer research? The US government and European governments could find that amount of money every year.
Alzheimer's is a warning tale. Lots of money flowed into research of this condition, and was mostly wasted on a flawed hypothesis supported by scientific VIPs who had a face to lose in case it proved incorrect.
We don't necessarily need more money in research, but smarter ways of spending it. The current grant system rewards established players and reliable production of mediocre (or even fraudulent) papers over honest failure and actual innovation too much.
This man is incredible. I wish I was 10% as smart, resilient, resourceful and determined as he is. Truly amazing stuff.
Thanks for posting this. Happy to answer questions!
They say to eat a healthy diet, exercise, get enough sleep, and avoid smoking/alcohol.
Have you discovered more specific reasons over the years?
Were you lacking in any of these?
The linked post about his treatment is basically a vanity article; low in useful information, but high in vague assertions and platitudes. There's also a link to a post griping about the red tape someone experienced while trying to self-treat their dog's cancer that's weird. I clearly live in a different world than these people.
This is a common trope in the tech field- successful tech person who is good at tech gets disease and wants to help cure it. It's easy to generate a lot of data these days (whole genome sequencing, various tests) but the reality is that turning that data into actionable knowledge is remarkably difficult. Much of the red tape exists to help people avoid making common mistakes that aren't obvious until you've been thro…
IIRC there is a cancer lab in Vienna, Austria, where they feed genome sequence of a tumor into an AI and it sometimes recommends unexpected-but-efficient treatments.