Earlier quoted context omitted.
Maybe they are in Canada. Name brand Ozempic is $230 CAD or $160 from Costco up here
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"Eschew flamebait. Avoid generic tangents."
GLP-1 drugs: An economic disruptor? (2024)
211–220 of 553 posts
Re: GLP-1 drugs: An economic disruptor? (2024)
#212Earlier quoted context omitted.
You can get wegovy generic for $299/mo and Zepbound generic for $399/mo currently through telemedicine via compounding pharmacies, without insurance.
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Can you please not harangue another user like this, regardless of how much you feel they should or shouldn't be spending?
Re: GLP-1 drugs: An economic disruptor? (2024)
#213Earlier quoted context omitted.
I've heard similar accounts and it sounds pretty wild. I'm not overweight and don't take anything but I do enjoy food. It would be horrible to me to lose the enjoyment of such a primal pleasure. If the choice is between being overweight and giving up the pleasure of eating altogether, I can imagine plenty of gourmands who would rather carry the extra weight for the physical and social pleasures of food. I've heard an…
Counter-anecdote. I have not lost my appreciation for good food, I just eat less of it. I used to be unable to leave any food on my plate regardless of how good or bad it was, now I’m perfectly happy to leave something uneaten if it isn’t to my taste.
Same for me, I don't recognise those symptoms (loss of taste, loss of impulses). My understanding is that all it does it to replicate the signal the stomach sends when it is full, and so you just feel full / a bit burpy, even on an empty stomach. But you do enjoy the same taste than before the drug.
That being said side effects vary and lots of people mention it gives them nausea. I can easily imagine how that would interfere with taste.
Re: GLP-1 drugs: An economic disruptor? (2024)
#214I started Tirzepatide 3-4 weeks ago. (Mostly as an experiment to understand the hype around GLP's... I don't have diabetes and only very slightly overweight at 20% body fat). Even at the lowest 2.5mg starter dose which you're only allowed to stay on for 1 month: - Extreme appetite suppression to the point where I've started calorie counting specifically to make sure that I'm eating enough. It's incredibly easy to for…
I've been on tirzepatide for 8 weeks (2.5mg then 5mg) and have a very similar conclusion as you. I started off at 160kg 8 weeks ago and now I'm down to 145kg. No other change in my lifestyle except eating radically less. Two 500-calorie-ish meals a day and some fruit as a snack, that's about it.
For decades I've struggled with diets but tirzepatide is the only thing that's made me stick with it. Will power alone wasn't enough, but with tirzepatide I'm very confident I'll get down to a under 100kg for the first time since I was a teenager, within a few months.
Re: GLP-1 drugs: An economic disruptor? (2024)
#215>Consider this: When alcohol consumption drops 40% (as it does for many people on these medications), we're not just talking about lower beer sales. We're talking about: Apparently in most muslim households this drops to 100% or zero consumption, you don't need freaking drugs for that
Converting to Islam feels like a bigger commitment than reading side effects of the drug you are about to take.
Re: GLP-1 drugs: An economic disruptor? (2024)
#216Is GLP-1 really changing general impulse control? But I do buy the argument. If impulse controlling drugs are going to be effective, the economic impact is basically not quantifiable... not only the economic impact but it would change society as a whole in extremely fundamental ways (e.g. dating)
There is not evidence to suggest general impulse control. That's extrapolation (beyond food items) and likely untrue IMHO.
Some comments below someone claimed the opposite... do you have any studies?
Re: GLP-1 drugs: An economic disruptor? (2024)
#217Earlier quoted context omitted.
> Even at the lowest 2.5mg starter dose which you're only allowed to stay on for 1 month... So they are going to force you onto a higher dose?!
Yes, up to 15 mg. Maintenance levels at 5, 10, and 15. If you cannot tolerate a maintenance level you can still get it, but insurance will not cover it ($1000/mo rather than $15/mo.) This is not an unreasonable situation. https://www.goodrx.com/zepbound/dosage
Hum, I don't know, here in the UK, no one is forcing you to do anything. I am free to chose if I want to step up, down or stay on the current dosage every month. And I took the cautious approach to only step up when I stopped feeling the effects at the current dosage, so 8 months in, I am only starting on 10mg (range is 2.5 to 15mg in 2.5 increments).
Re: GLP-1 drugs: An economic disruptor? (2024)
#218Interesting, but I’m not sure I buy it. I certainly don’t think Simon is preparing for this massive economic shift; I think they’re reacting to an existing trend. > America's largest mall operator, Simon Property Group, is converting anchor stores into medical centers and wellness spaces. They're doing this because they recognize the writing on the wall. Malls have been dying for years, and COVID felt like the nail i…
Malls around DC are crazier than ever. But I am not sure if people are spending money or not.
It's straight up miserable to be in mclean/tysons between october and february. Truly it is america's asshole. And yes, people conspicuously consume more than ever. I think this is likely not true of most malls, though, the shopping culture here is just nuts.
Re: GLP-1 drugs: An economic disruptor? (2024)
#219Off topic: Since we are doing clickbait titles, I thought ChatGPT / Gen AI in general might be a better candidate for "the biggest economic disruptor since the internet", based on hype, especially from the "leaders" who claim that AGI is just a few months away.
Re: GLP-1 drugs: An economic disruptor? (2024)
#220The article describes a psychotic lifestyle as normal.
I didn't need a drug to reject having breakfast at Starbucks. I bake my own bread. I wake up early to have time to eat it in peace. I take enough time to roast my own coffee beans. I commute by bike.
It's about having some standards. A concept of a lifestyle and person that isn't just a corpo drone.