Live data from Hacker News

Most life on Earth is dormant, after pulling an 'emergency brake'

quantamagazine.org

211–220 of 253 posts

Re: Most life on Earth is dormant, after pulling an 'emergency brake'

#211
post #51

Earlier quoted context omitted.

The real trick is being somebody that a future generation will go to the trouble of defrosting.

If we found a crypt of a hundred well-preserved mummies from a few thousand years ago who for all we could tell were basically peasants in their lifetimes, not grand or interesting people, and we had the ability to revive them into the modern world, I still think we would. The "interest" factor of future generations reviving cryonics customers when it's possible to do so is like the weakest factor in trying to predic…

That's probably a motivating factor for defrosting your first few hundred/thousand mummies, but would the "interest" factor still be there for the millionth mummy?

Re: Most life on Earth is dormant, after pulling an 'emergency brake'

#212
post #5

I'm having visions of old people freezing their bodies and inducing "dormancy" so they can wake up when the world is a better place. I would invest in that company.

What if they wake up and the world is a worse place? You're making a big bet that people in the far future will look at your preserved body as a resource to cherish, not one to be exploited.

I recall reading a Jack Vance novel where cannibals used cryogenic sleepers as a convenient supply of preserved food.

Re: Most life on Earth is dormant, after pulling an 'emergency brake'

#213

Earlier quoted context omitted.

> The most exciting phrase to hear in science, the one that heralds new discoveries, is not "Eureka!" (I found it!) but "That's funny..." -- commonly attributed to Isaac Asimov

As a one-time scientist, I think Asimov may have been tricked by extreme selection bias on "That's funny..." utterances. It almost always precedes a crushing realization that you have fucked something up and probably wasted a lot of time. You're probably days down exploring that explanation before the eventual "holy shit" (that I never really had the benefit of experiencing).

The most exciting phrase that heralds a new discovery is not "eureka!" but "holy shit!"

Re: Most life on Earth is dormant, after pulling an 'emergency brake'

#215
post #63

Earlier quoted context omitted.

> only the Inuit for example do not need sun, to produce Vitamin D btw As far as I can tell, they need vitamin D just like any other life form and can only synthesise it from the sun, just like all other lifeforms on Earth. They might have adapted to reduced amounts of available vitamin D though[0], because they don't have much of it available to them in the first place and because there's really no other source than…

Humans cannot synthesise vitamin D, but we can acquire it through diet from other sources, including particularly fresh fish, which are abundant in Inuit diets. Note that numerous of the sources listed here are fortified (that is, have additional vitamin D added), however it does occur naturally in some sources as well: https://www.dietaryguidelines.gov/resources/2020-2025-dietar... >

What? I’ve never heard claim of this, we require sunlight (UV) as input but yes we do synthesize it. I mean the human body can’t spontaneously create anything, but it can take precursors and make various vitamins, proteins, and fats… https://en.wikipedia.org/wiki/Vitamin_D#Biosynthesis

Re: Most life on Earth is dormant, after pulling an 'emergency brake'

#216

Earlier quoted context omitted.

Humans cannot synthesise vitamin D, but we can acquire it through diet from other sources, including particularly fresh fish, which are abundant in Inuit diets. Note that numerous of the sources listed here are fortified (that is, have additional vitamin D added), however it does occur naturally in some sources as well: https://www.dietaryguidelines.gov/resources/2020-2025-dietar... >

What? I’ve never heard claim of this, we require sunlight (UV) as input but yes we do synthesize it. I mean the human body can’t spontaneously create anything, but it can take precursors and make various vitamins, proteins, and fats… https://en.wikipedia.org/wiki/Vitamin_D#Biosynthesis

Obvious omission from my prior comment: in the absence of sunlight. I'd hoped that would be clear from context, it's an oversight on my part.

That is, either sunlight or dietary supplementation will provide the essential vitamin/hormone D (its biological function is ... interesting).

Which is to say, deprivation of either sunlight or dietary sources of themselves is not sufficient to induce vitamin D deficiency. There's also the fact that as an oil-based vitamin, can be, and is, stored for prolonged periods in body tissues. That's a sharp contrast to the water-soluable vitamin C of which excess is excreted in urine.

This was responding specifically to the prior claim "they need vitamin D just like any other life form and can only synthesise it from the sun" (emphasis added) by seszett here: https://news.ycombinator.com/item?id=40594479> The apparent claim that sunlight is necessary for acquisition of vitamin D is incorrect.

Periodic hypersupplementation of D can be effectively processed and retained by the body. By contrast, hyperdosing of vitamin C is a waste of resources as the excess is not retained and is flushed out. I've read previously that long-term injections of vitamin D have been effectively used, see:

"Lasting Moderate Increases in Serum 25-Hydroxvitamin D Levels and Shorter-Term Changes in Plasma Calcium " https://pubmed.ncbi.nlm.nih.gov/28492140/>

"Vitamin D Injections: Benefits, Side Effects, and Who Is a Candidate? " https://healthnews.com/nutrition/vitamins-and-supplements/vi...>

(Neither of these is the specific item I'd had in mind, though both describe similar procedures and efficacy.)

(Overconsumption of various vitamins and minerals can be harmful in other ways as well, I'm not a doctor (not even of philology) and moreover I'm not your doctor.)

Re: Most life on Earth is dormant, after pulling an 'emergency brake'

#217

Earlier quoted context omitted.

Humans cannot synthesise vitamin D, but we can acquire it through diet from other sources, including particularly fresh fish, which are abundant in Inuit diets. Note that numerous of the sources listed here are fortified (that is, have additional vitamin D added), however it does occur naturally in some sources as well: https://www.dietaryguidelines.gov/resources/2020-2025-dietar... >

> The major natural source of vitamin D is synthesis of cholecalciferol in the lower layers of the epidermis of the skin, through a photochemical reaction with Ultraviolet B (UV-B) radiation from sun exposure or UV-B lamps.[ https://en.wikipedia.org/wiki/Vitamin_D

Yeah, very poor wording on my part as I was addressing the false claim in GP that only sunlight-based synthesis would provide vit-D. Diet is an alternate source. More in my other follow-up response.

Re: Most life on Earth is dormant, after pulling an 'emergency brake'

#218

Earlier quoted context omitted.

Humans cannot synthesise vitamin D, but we can acquire it through diet from other sources, including particularly fresh fish, which are abundant in Inuit diets. Note that numerous of the sources listed here are fortified (that is, have additional vitamin D added), however it does occur naturally in some sources as well: https://www.dietaryguidelines.gov/resources/2020-2025-dietar... >

It might seem like a cheat, but healthy humans can photosynthesize (metaphorically) vitamin D. It's one of the free lunches our bodies have, if you ignore sun damage.

See: https://news.ycombinator.com/item?id=40604537>.

Agreed, and what I was trying to say was that sunlight isn't the exclusive route.

Re: Most life on Earth is dormant, after pulling an 'emergency brake'

#219

> Karla Helena-Bueno discovered a common hibernation factor when she accidentally left an Arctic bacterium on ice for too long. I love how this story follows the magic pattern of so much of innovation and discovery - an accident. It's refreshingly human and not a mode of discovery that machine learning is going to completely take away from us.

I've been using the humble refrigerator/freezer for accidental bacterial science experiments all my life.

(I vividly remember as a kid leaving a slice of bread in the refrigerator as a for-credit experiment until it grew interesting green mold to study)

Re: Most life on Earth is dormant, after pulling an 'emergency brake'

#220
post #34
post #5

I'm having visions of old people freezing their bodies and inducing "dormancy" so they can wake up when the world is a better place. I would invest in that company.

If too many not so old people would use it, the effects might be not great: https://xkcd.com/989/

I have a feeling most people rushing to be first in line to freeze themselves for non-terminal-illness-reasons are probably not high productivity individuals.
Post reply on HN