Novo Nordisk facing pressure as study finds $1k drug can be made for $5 • Hacker News Board

Re: Novo Nordisk facing pressure as study finds $1k drug can be made for $5

#211

Post by pfdietz » Sun, Mar 31, 2024, 2:42 PM UTC

ponector wrote: post #207

gtvwill wrote: post #103

Earlier quoted context omitted.

Rental markets rooted where I am. Fails to provide for society the purpose it exists for. So yeah if your saying big pharma is the same sure I'm on board. Profit enough to survive. But don't take more than your worth. Tbh profiting off medicine is about as low as profiting off weapons manufacturing. You literally make money out of the misery of others. Thank f#@k I live in a country that has free healthcare. The conc…

Free healthcare is not really free. And it is good until you hit the point where the next available appointment date is 12+ months ahead.

Or when your country decides the benefit of treating you with the new treatment doesn't justify the cost. I understand this is quite common in Europe with some cancer treatments.

Re: Novo Nordisk facing pressure as study finds $1k drug can be made for $5

#212

Post by pfdietz » Sun, Mar 31, 2024, 2:44 PM UTC

datavirtue wrote: post #144

karles wrote: post #9

Producing it is not the hard part. Researching it is... And you are not paid for your research "up front". It's added to the cost afterwards.

Marketing spend dwarfs (dwarves?) R&D costs by multiple factors.

I believe that claim ignores the R&D that is occurring in small companies. The large companies are good at marketing, so they buy small companies that have a hit, and then market it. The large purchase price they pay for the small companies reflects all that R&D that was done by the small companies (including the ones that didn't get a hit and weren't purchased.)

Re: Novo Nordisk facing pressure as study finds $1k drug can be made for $5

#213

Post by pfdietz » Sun, Mar 31, 2024, 2:52 PM UTC

sschueller wrote: post #156

[flagged]

Yes, the eat and exercise thing has never been tried. Why didn't anyone think of this first?

Next up, the "just don't do bad things" approach to improving society. It's genius!

Re: Novo Nordisk facing pressure as study finds $1k drug can be made for $5

#214

Post by [deleted] » Sun, Mar 31, 2024, 3:58 PM UTC

Cupprum wrote: post #132

lvl102 wrote: post #90

Who educates these scientists through PhD programs? Oh, OK. So we are paying these people to get their PhDs so they can go and start a company to scalp people with drugs that deliver 10% lift in efficacy. What a scam model.

How much do you know about this? Novo Nordisk sponsors many universities around Denmark, they pay a lot of money for those graduates.

[deleted]

Re: Novo Nordisk facing pressure as study finds $1k drug can be made for $5

#215

Post by dang » Sun, Mar 31, 2024, 4:39 PM UTC

Unfrozen0688 wrote: post #19

[flagged]

You've been breaking the site guidelines so frequently with this account that I think we have to ban it. Can you please not create accounts to break HN's rules with? We're trying for something a bit different here than internet default, and would appreciate your help.

https://news.ycombinator.com/newsguidelines.html

Re: Novo Nordisk facing pressure as study finds $1k drug can be made for $5

#216

Post by Wytwwww » Sun, Mar 31, 2024, 8:46 PM UTC

paulmd wrote: post #205

Wytwwww wrote: post #169

Earlier quoted context omitted.

That's a 10 year old article. Although if we rank by market cap top 6 are from the US these days (by revenue 5 out 10 seem to be European) so not much has seemingly changed (besides Novo Nordisk becoming the second most valuable pharma company out of nowhere)

> That's a 10 year old article. Although [the] top 6 are from the US these days […] so not much has seemingly changed Well, thanks for the update. Correcting a citation an out-of-date article that is - as you admit - apparently still relevant as cited was definitely worth everyone’s time.

The very specific figures from that comment are obviously not really correct. e.g. Pfizer's profit margin in 2023 was ~3.5% which isn't that great (and that's the largest pharma company by revenue).

Re: Novo Nordisk facing pressure as study finds $1k drug can be made for $5

#217

Post by sschueller » Mon, Apr 01, 2024, 1:49 PM UTC

pfdietz wrote: post #213

sschueller wrote: post #156

[flagged]

Yes, the eat and exercise thing has never been tried. Why didn't anyone think of this first? Next up, the "just don't do bad things" approach to improving society. It's genius!

Stop making excuses, a large part of the world does not have an obesity epidemic. Ozempic has it's uses but only a very small percentage of the population actuality need it.

Same goes for the masses of men over 30 that think they need testosterone replacement therapy. Unless you abused steroids or you have an underlying issues that prevents your gonads from working you do not need it. In fact a major factor in low testosterone is excessive body weight.

Re: Novo Nordisk facing pressure as study finds $1k drug can be made for $5

#218

Post by kwhitefoot » Wed, Apr 03, 2024, 1:06 PM UTC

quotemstr wrote: post #140

kwhitefoot wrote: post #129

Earlier quoted context omitted.

Wouldn't be better for people to simply eat better? Obesity levels are much lower in Norway than they are in the UK and US. As far as I can tell this is because in Norway we simply eat less fast and ultraprocessed food.

> Wouldn't be better for people to simply eat better? Has a half-century of telling people to "simply eat better" worked?

I didn't say anything about telling people to eat better. Perhaps what might work would be to make good healthy food more available and affordable and the rubbish less affordable and less available.