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Vitamin D and Depression (2020)

ncbi.nlm.nih.gov

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Re: Vitamin D and Depression (2020)

#211

Post by LinuxBender »

ekianjo wrote: post #206
TameAntelope wrote: post #169

Earlier quoted context omitted.

It is more correct than the research that shows otherwise.

If you skin produces dozens of thousands of IU while staying 20 minutes in the sun, and the RDA is not even a tenth of that, I'd rather wage the RDA is completely wrong and misplaced.

Type 1 skin is 2000 IU's per hour if completely exposed to the sun though someone may call the cops. Type 5 skin is 500 IU's per hour but all of this is moot if one does not have sufficient precursor elements for the D3 process to occur. This involves vitamin D2, C, collagen and a few other elements. I don't remember the whole chain off the top of my head. I'm lazy and just take pills.

Re: Vitamin D and Depression (2020)

#212

Post by canucker2016 »

canucker2016 wrote: post #152
slaymaker1907 wrote: post #137

Earlier quoted context omitted.

There's also ample evidence that 1500mg is too low. https://www.webmd.com/food-recipes/news/20140402/cdc-salt-gu... . Unlike white sugar which seems to be bad for humans in nearly any amount, salt is an essential nutrient. I suspect it was so demonized as an attempt to deflect blame off of other food additives such as sugar. Low sodium diets may make sense for people with high blood pressure, but it isn't something t…

It's not the total amount of sodium but the concentration of the dose of sodium which will affect your blood pressure. see https://www.youtube.com/watch?v=LbSic4Oo8ME&t=420s So if your food tastes salty, you should drink more water to dilute the concentration (and hopefully you won't drink so much water to induce hyponatremia - it's a balancing act).

Later in the above-mentioned YouTube video, the doctor mentions that drinking water before you get that thirsty feeling is better for you.

By the time you get the thirsty feeling, your body has switched over to converting glucose to fructose, etc.

Re: Vitamin D and Depression (2020)

#213

Post by gabereiser »

AnthonBerg wrote: post #192
gabereiser wrote: post #45

Earlier quoted context omitted.

You, sir, just blew my mind. I have some reading material to go through. This is fascinating indeed!!

I’m so glad to be able to share these papers with someone! I have no formal higher-level education in biology btw. Just high-school level or so? And I had no idea this was a thing – I just found one of these papers purely by accident. I don’t even remember what I was digging for on Google Scholar. I think it was something related to psoriasis. (It runs in the family.) I think I might have been trying to look for any…

I'm glad you're getting to the bottom of your health issues. Sounds like you're on the right track.

I'm fascinated by it because of my history:

I've had acne my whole life. Starting at 11, I'm 39 now. Still have it. I've tried every medication known to man. Nothing works. Dermatologists can't explain it, they just give me the same canned answer "You produce too much sebum". "Ok, how can we control that?". "We're trying".

I take two showers a day to try to ward off the sebum oil from clogging my pores. I wash my face, hands, and all multiple times a day and wipe with clinical strength salicylic acid (6% instead of 3% you can get over the counter).

Still, nothing works. Except one thing which could have adverse affects on me later. The Sun.

When I get a tan, all my acne clears up for a brief while. Maybe that's the cis-urocanic acid doing it's thing. Maybe it's the sun burning that sebum and sealing the pore. I'm not sure. I'm pretty sure I'll get skin cancer if I continue this line of "treatment" but I'm out of options. It's ridiculous.

It's on my face, my arms, my back, my ass, my legs, my chest and has been since middle-school. I'm ready to just graft the whole body.

So thanks again as I have some other avenues to discuss with my doctors as well as some research to show them.

Re: Vitamin D and Depression (2020)

#214

Post by beowulfey »

TameAntelope wrote: post #204
beowulfey wrote: post #175

Earlier quoted context omitted.

You should never judge an article by where it was published (some exceptions of course), only in the quality of the work. Impact factors are loosely a measurement of significance of the work, in terms of how broadly applicable they are to the fields of science. It is absolutely not a strict measure of the expected quality of the article. Also, for what it's worth, most of the articles referenced in the Harvard Medici…

And why should I trust you? You've given a decree, "Thou shalt not judge a paper based on where it was published!" and then don't give any reasons why that would be the case. Also, I'm not qualified to judge a paper by its work quality, I need to rely on the experts in the field for that, and a decent proxy for that judgement is where a paper gets published, so by looking at where a paper was published, I am judging…

Sorry, I thought my reason was clear from my comment. I did not intend it as a decree you should follow blindly. I’ll expand on my explanation.

Impact factor is not a measurement of an individual article’s quality. It is a summary statistic, a rough measurement for how frequently that particular journal gets cited in other journals.

By judging an individual article by the impact factor of its journal, without reading the article and determing its quality yourself, you bias yourself to whatever those results might be one way or another with a statistic not intended to relay any information about the journal article itself.

You are right that it is a decent proxy where higher impact tends to have better journal quality (anecdotal, but I have observed this for sure) but I got annoyed when you claimed an article published in a low impact journal had no merit. That is simply not the case.

You can have the best, high quality scientific study ever about a highly specific thing, but because it is so specific you won’t have the broad impact that would get into one of the top tier journals. But with your viewpoint, that study would get thrown out the window.

Re: Vitamin D and Depression (2020)

#215

Post by eashman »

gabereiser wrote: post #213
AnthonBerg wrote: post #192

Earlier quoted context omitted.

I’m so glad to be able to share these papers with someone! I have no formal higher-level education in biology btw. Just high-school level or so? And I had no idea this was a thing – I just found one of these papers purely by accident. I don’t even remember what I was digging for on Google Scholar. I think it was something related to psoriasis. (It runs in the family.) I think I might have been trying to look for any…

I'm glad you're getting to the bottom of your health issues. Sounds like you're on the right track. I'm fascinated by it because of my history: I've had acne my whole life. Starting at 11, I'm 39 now. Still have it. I've tried every medication known to man. Nothing works. Dermatologists can't explain it, they just give me the same canned answer "You produce too much sebum". "Ok, how can we control that?". "We're tryi…

I assume you looked into Accutane treatment? It has worked wonders for multiple people I know.

Re: Vitamin D and Depression (2020)

#216

Post by michaelcampbell »

alwillis wrote: post #154
slaymaker1907 wrote: post #137

Earlier quoted context omitted.

There's also ample evidence that 1500mg is too low. https://www.webmd.com/food-recipes/news/20140402/cdc-salt-gu... . Unlike white sugar which seems to be bad for humans in nearly any amount, salt is an essential nutrient. I suspect it was so demonized as an attempt to deflect blame off of other food additives such as sugar. Low sodium diets may make sense for people with high blood pressure, but it isn't something t…

I recently listened to a great podcast [1] on the importance of salt and its role in proper brain functioning—the host is a tenured professor of Neurobiology and Ophthalmology at Stanford. Part of the into: Additionally, I examine research findings suggesting that some individuals might benefit from increased intake of sodium and other electrolytes (magnesium and potassium) to enhance mental performance, lessen anxie…

I'm a little shocked at only 2 mentions so far of Huberman on this topic. As you know he goes into great detail here, and a panoply of related health issues.

Re: Vitamin D and Depression (2020)

#217

Post by Projectiboga »

lordentropy wrote: post #12

Daily morning and afternoon exposure to bright light might actually be more important to reducing depression than direct vitamin D supplementation. Low vitamin D might just be an indicator that you are not getting enough sunlight. Sunlight also affects melatonin and serotonin levels, and synchronizes your Circadian rhythm. Not sure why that article doesn't talk about Seasonal affective disorder (SAD), and how bright…

Sunlight direct on the retina either without any obstructions or only through eyelids loads an enzyme necessary for serotonin production. The required amount of sunlight on the retina to reduce depression is 3 or more 20-30 minute sessions. It is actually harder than it might seem to get that much every week.

Re: Vitamin D and Depression (2020)

#218

Post by gabereiser »

eashman wrote: post #215
gabereiser wrote: post #213

Earlier quoted context omitted.

I'm glad you're getting to the bottom of your health issues. Sounds like you're on the right track. I'm fascinated by it because of my history: I've had acne my whole life. Starting at 11, I'm 39 now. Still have it. I've tried every medication known to man. Nothing works. Dermatologists can't explain it, they just give me the same canned answer "You produce too much sebum". "Ok, how can we control that?". "We're tryi…

I assume you looked into Accutane treatment? It has worked wonders for multiple people I know.

I was on Claravis for 8 months with no improvement. Still looking for a remedy, even if just temporary.

I will say that initially Accutane worked. For the first few months it cleared up the acne on my face but after a few more months it came back with a vengeance.

Re: Vitamin D and Depression (2020)

#219

Post by BiteCode_dev »

scruple wrote: post #145
phkahler wrote: post #113

Earlier quoted context omitted.

>> The medical community is full of contradictions. We added iodine to salt to prevent deficiency, then decades later told everyone to avoid salt. I've found iodine to be a huge piece of the puzzle - certainly not a panacea but one of several go to solutions.

Cranberries are how I get iodine into my diet. Not-from-concentrate Cranberry juice from TJs, primarily.

Didn't know cranberries contained it. How much every day do you drink ?

Re: Vitamin D and Depression (2020)

#220

Post by kingcharles »

hattmall wrote: post #165
kingcharles wrote: post #67

Earlier quoted context omitted.

I just went over 8 years without seeing the sun (jail). I wonder what the long term effects are?

Gahdam, they never put you on the yard?

First 5 years was in a facility with no windows or access to the outside. Last 3 had windows that were too dirty to see out of but some feeling of sunlight came in. That facility had outside, but was allowed out probably 5 hours in total. I burned instantly after all that time without sunlight!
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