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Post-SSRI sexual dysfunction

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Re: Post-SSRI sexual dysfunction

#211

Post by mjevans »

FFRefresh wrote: post #118
n8cpdx wrote: post #113

As someone dating in their 20s, it is getting hard to find people who aren’t having SSRI-related dysfunction. Recently met an older (early 30s guy) and it was seriously cool having a sexual experience that didn’t end with “don’t bother I’m just not going to finish no matter how long we go.” They really seem to be handing out these serious, almost-impossible-to-withdraw medications like candy on Halloween. They don’t…

I do wonder if there's a culture-wide bug/meme with regards to mental health (and beyond) that makes it hard to push for lifestyle changes at scale. I think one such meme is around agency, with the underlying meme being that humans have no control over their circumstances or mental state. They have anxiety or they have depression. It's part of their identity, and these seem to be thought of as immutable diseases. And…

Consider a hypothetical solution.

There's a place similar to 'college' but focused on adults. Admittance to that college is free. Anyone can attend. Room, board, meal plan. At least some classes must be attended; though the term 'class' is vague. For some a class might just be seeing a councilor to talk things over, or some other doctor prescribed treatment routine.

Some of the classes should be group activities that are cooperation based rather than rivalry based. The focus should be on establishing the expectation of positive interactions and experiences. Also about helping to train people to respond to others in the same way.

Suddenly, I think I'm describing kindergarten for adults from an amateur psychological perspective.

Re: Post-SSRI sexual dysfunction

#212

Post by bongoman37 »

LorenPechtel wrote: post #196
n8cpdx wrote: post #113

As someone dating in their 20s, it is getting hard to find people who aren’t having SSRI-related dysfunction. Recently met an older (early 30s guy) and it was seriously cool having a sexual experience that didn’t end with “don’t bother I’m just not going to finish no matter how long we go.” They really seem to be handing out these serious, almost-impossible-to-withdraw medications like candy on Halloween. They don’t…

The doctors don't seem to care about the side effects. All the psych drugs have horrendous side effects which get basically ignored. I've even seen multiple suggestions that mass shootings might be a rare side effect from them.

These drugs are prescribed all over the world. Mass shootings happen in just one country.

Re: Post-SSRI sexual dysfunction

#213

Post by jnovek »

tata71 wrote: post #64
Jaruzel wrote: post #22

My personal anecdote: I'm on Venlafaxine which is an SNRI (also cited in the article), and I definitely suffer some of those side-effects. It sucks. At times it makes me want to shy away from sex completely. Other times I think I'm doing OK, only to find out I can't finish, or I finish weakly with no adrenalin rush. So my choices are, come off the pills, and emotionally go down a dark well I may not come out of, or k…

Is this the only drug/treatment you've attempted to combat the dark well with? This is not medical advice, only anecdotal interest, but, have known many to leave SSRI for well-timed CBD oil. Wonder if issues requiring an SNRI are "similar" enough? Wishing you well!

Cannabinoids are a promising future treatment for depression; however, right now they are unproven.

There is already stigma associated with being on antidepressants. The consequences of discontinuing SSRIs or SNRIs can range from catastrophic to deadly. Please keep in mind that posts promoting alternative treatments can add to that stigma.

Re: Post-SSRI sexual dysfunction

#214

Post by gtirloni »

heavyset_go wrote: post #208
Jaruzel wrote: post #22

My personal anecdote: I'm on Venlafaxine which is an SNRI (also cited in the article), and I definitely suffer some of those side-effects. It sucks. At times it makes me want to shy away from sex completely. Other times I think I'm doing OK, only to find out I can't finish, or I finish weakly with no adrenalin rush. So my choices are, come off the pills, and emotionally go down a dark well I may not come out of, or k…

There are two medications on the market that have FDA approval for the claim that they have lower incidences of sexual side effects than other similar medications. One is vortioxetine and the other is vilazodone. In addition to acting as SSRIs, they have high affinities for 5HT1A autoreceptors, activation of which disinhibits the release of neurotransmitters. SSRI sexual side effects are hypothesized to be the result…

Does it mean they don't also inhibit LSD effects like Venlafaxin does?

Re: Post-SSRI sexual dysfunction

#215

Post by _ktx2 »

User23 wrote: post #209
_ktx2 wrote: post #193

Earlier quoted context omitted.

I was on SSRIs for a time until my thoughts became so irreversibly cloudy that I weened off and stopped. After that I coincidentally stopped drinking, my weight dropped, and now I've stopped using weed for the most part. My anxiety doesn't go away, even if I go ride my bike for hours. The things that give me anxiety are largely social. How people think of me at work, my appearance, what women think of me, and how the…

> I was on SSRIs for a time until my thoughts became so irreversibly cloudy that I weened off and stopped. After that I coincidentally stopped drinking, my weight dropped, and now I've stopped using weed for the most part. My anxiety doesn't go away, even if I go ride my bike for hours. You may want to try a primarily anaerobic exercise like lifting weights to supplement your cardio. Your mileage may vary, but I pers…

I definitely have healthy friendships, I was just sharing a learning.

Re: Post-SSRI sexual dysfunction

#216

Post by serene_venture »

n8cpdx wrote: post #113

As someone dating in their 20s, it is getting hard to find people who aren’t having SSRI-related dysfunction. Recently met an older (early 30s guy) and it was seriously cool having a sexual experience that didn’t end with “don’t bother I’m just not going to finish no matter how long we go.” They really seem to be handing out these serious, almost-impossible-to-withdraw medications like candy on Halloween. They don’t…

The stereotype is that younger people aren’t having sex. Maybe we will look back and realize we medicated away a generation of relationship building.

Re: Post-SSRI sexual dysfunction

#217

Post by heavyset_go »

gtirloni wrote: post #214
heavyset_go wrote: post #208

Earlier quoted context omitted.

There are two medications on the market that have FDA approval for the claim that they have lower incidences of sexual side effects than other similar medications. One is vortioxetine and the other is vilazodone. In addition to acting as SSRIs, they have high affinities for 5HT1A autoreceptors, activation of which disinhibits the release of neurotransmitters. SSRI sexual side effects are hypothesized to be the result…

Does it mean they don't also inhibit LSD effects like Venlafaxin does?

LSD activates 5HT2A. Mirtazapine is the only medication I posted about that blocks 5HT2A.

I'm not sure what the mechanism behind venlafaxine's blunting effect on LSD is.

Re: Post-SSRI sexual dysfunction

#218

Post by [deleted] »

n8cpdx wrote: post #113

As someone dating in their 20s, it is getting hard to find people who aren’t having SSRI-related dysfunction. Recently met an older (early 30s guy) and it was seriously cool having a sexual experience that didn’t end with “don’t bother I’m just not going to finish no matter how long we go.” They really seem to be handing out these serious, almost-impossible-to-withdraw medications like candy on Halloween. They don’t…

[deleted]

Re: Post-SSRI sexual dysfunction

#219

Post by jagger27 »

n8cpdx wrote: post #113

As someone dating in their 20s, it is getting hard to find people who aren’t having SSRI-related dysfunction. Recently met an older (early 30s guy) and it was seriously cool having a sexual experience that didn’t end with “don’t bother I’m just not going to finish no matter how long we go.” They really seem to be handing out these serious, almost-impossible-to-withdraw medications like candy on Halloween. They don’t…

This is one of the most selfish, unsympathetic, and dismissive comments I have read on this website.

You really don’t have a clue why people reach for these drugs.

Re: Post-SSRI sexual dysfunction

#220

Post by cobertos »

heavyset_go wrote: post #208
Jaruzel wrote: post #22

My personal anecdote: I'm on Venlafaxine which is an SNRI (also cited in the article), and I definitely suffer some of those side-effects. It sucks. At times it makes me want to shy away from sex completely. Other times I think I'm doing OK, only to find out I can't finish, or I finish weakly with no adrenalin rush. So my choices are, come off the pills, and emotionally go down a dark well I may not come out of, or k…

There are two medications on the market that have FDA approval for the claim that they have lower incidences of sexual side effects than other similar medications. One is vortioxetine and the other is vilazodone. In addition to acting as SSRIs, they have high affinities for 5HT1A autoreceptors, activation of which disinhibits the release of neurotransmitters. SSRI sexual side effects are hypothesized to be the result…

Vortioxetine (Trintellix) is expensive as fuck, most insurance plans have it under multiple restrictions (step therapy (ST), prior auth (PA), others). They have a manufacturer discount card to take off $100 max but if your prescription benefits don't kick in until after you're deductible you will max out every year pretty quickly. I just paid $900 for a 3 month supply.

But... Anecdotally, it does have less sexual side effects than escitalopram (Lexapro), and helps about the same amount with anxiety as escitalopram (Lexapro), though maybe a little bit less effective at that.

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