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Pfizer and Moderna vaccines may produce lasting immunity

nature.com

211–220 of 364 posts

Re: Pfizer and Moderna vaccines may produce lasting immunity

#211
Someone should find out if natural antibodies provide long term immunity, including variants, since so many people already contracted Covid-19 and recovered.

Especially among young adults teenagers and children since they have yet to be vaccinated at scale.

Re: Pfizer and Moderna vaccines may produce lasting immunity

#212

Earlier quoted context omitted.

Good antibody tests are extremely (99%) accurate in verifying previous infection, not sure why you're claiming the opposite...? And while vaccination is safe and easy to get , both me and a lot of my friends were basically as sick as a regular flu for a day or two from it. Some people have no reaction, which is wonderful, but a lot of people need to take a sick day or two, or intentionally get the vaccine on a Friday…

How long after infection will an antibody test work? I have had 2 instances of suspected Covid infection, one where my friend who I had met outside for a walk actually tested positive. The latest was probably November 2020. Would I still be able to identify infection with the antibody test?

There's no simple answer. It really depends on severity of symptoms, length of the disease course, and immune system response. Some patients never produce detectible levels of antibodies, in others they may persist for years.

Patients who receive a negative antibody test after a suspected COVID-19 case might want to get a T cell test since that is another way to confirm previous infection.

https://www.fda.gov/news-events/press-announcements/coronavi...

Re: Pfizer and Moderna vaccines may produce lasting immunity

#213
post #186

Earlier quoted context omitted.

There's no basis to believe at this point that we'll need "booster shots" of any kind with COVID vaccination, and in fact the opposite seems to be the case, so this comment is being downvoted for spreading misinformation (amusingly, this specific comment will probably be disliked by both vaccination proponents and disease proponents :) The reason we won't need yearly vaccinations as with the flu shots isn't a propert…

How do I reconcile this with the existence of, say, Moderna booster? https://investors.modernatx.com/news-releases/news-release-d... (Genuine question.)

Of course the manufacturers would love for there to be a need for a booster for every man, woman, and child on Earth!

Re: Pfizer and Moderna vaccines may produce lasting immunity

#214
post #194

Earlier quoted context omitted.

> I'm up in Canada where vaccine hesitancy has been almost unheard of[1] and those who refuse to get vaccinated, excepting those that can't for medical reasons, are ostracized for their overtly selfish actions. In other words, those who value individual freedom might want to avoid Canada for its over-boarding groupthink and overtly collectivist mentality.

I actually strongly disagree with this point. America has a very precise definition of individual freedom that I disagree with - it's a big part of why I emigrated. In the US you're absolutely free to die as you wish - in Canada you're free to live a healthy life and do with that life what you may. Socialism and socialized healthcare frequently gets painted as being anti-freedom but I think that the lack of socialize…

Lack of socialized healthcare? The USA has at least 3 times as many people on government healthcare than the entire population of Canada (Medicare, Medicaid, the VA). The USA has the second- third-largest government-run healthcare system in the world.

As a person who lived 20 years in Canada and 14 in the USA, I'll take the USA every day of the week--and for the past year I've paid for my own health insurance directly.

Canada's healthcare system is run by bureaucrats who prioritize many items ahead of citizen health.

Here's one example: A family member is a police officer. While I was visiting home, in Ontario, he was hit with some insane shoulder-related pain. This is one tough guy and he was reduced to tears--some kind of nerve damage or something.

The hospital in Canada told him he needed an MRI. And that it would take between 4 and 6 months til there was an available slot. They gave him a prescription for strong opiates to manage the pain during his wait.

I drove him over the border to Buffalo, shelled out $500, and he had his MRI in less than half an hour. The drive was longer than the wait in the radiology clinic.

There are tradeoffs in every situation. I think Canada's healthcare system is better in one exact way: Nobody's bankrupted of their financial wealth due to healthcare. But many many many Canucks are bankrupted of their actual health, their time, their human wealth, due to healthcare.

Re: Pfizer and Moderna vaccines may produce lasting immunity

#215

Earlier quoted context omitted.

The Wall Street Journal reported Friday that about half of adults infected in an outbreak of the delta variant in Israel were fully vaccinated with the Pfizer-BioNTech vaccine Source CNBC.

Is this intended as a counterpoint, or a point in support? People have been pretty loose with their "therefore" about this Israel snippet. After all, if 100% of Israel had been vaccinated with Pfizer, then 100% of adults infected with Delta would have been fully vaccinated. I'm sure the raw number of people infected with Delta is way down compared to what it would have been w/o vaccination though.

This is a frequent anti-vaxx talking point that well predates COVID-19. In most outbreaks in highly vaccinated populations, most of the cases will be in the vaccinated. We see this for measles and pertussis all the time. The rate will be much lower though.

Re: Pfizer and Moderna vaccines may produce lasting immunity

#216
post #69

Earlier quoted context omitted.

It's quite irresponsible to try and coerce people who don't need treatment to accept it as well

No it isn't - it's providing unified and clear guidance on vaccination. I'm up in Canada where vaccine hesitancy has been almost unheard of[1] and those who refuse to get vaccinated, excepting those that can't for medical reasons, are ostracized for their overtly selfish actions. The US, though, has a real problem with disinformation being accepted more readily than fact. I am fine with the theory of having a nuanced…

This has nothing to do with what I said. You are reacting to anti-vaccine views other people have that are not expressed in my comment. I said that _if_ Covid-19 infection confers equal levels of protection to vaccination then it is irresponsible to try and coerce people who have been infected to get vaccinations they don't need. I have said nothing about anything else. If you have issues with what those people have said you should take it up with them

Re: Pfizer and Moderna vaccines may produce lasting immunity

#217

Earlier quoted context omitted.

How sure are you about the long term effects of COVID?

Oh, not very sure at all. However, I may have already have it, so that cat's out of the bag (and invalidates any reason to get the vaccine anyways). Or I may never get it. Taking the vaccine, which includes three brand new medical technologies and has not completed phase3 trial, guarantees me taking that risk. I am extremely healthy, have a great diet, and as a farmer, I get plenty of time soaking up vitamin D, a pot…

You have no clue what you are talking about and have spouted multiple falsehoods in your comment, especially in regards to phase 3 trials not being completed (they are) and that they are not conducting follow ups for an extended period of time (again, they are).

https://www.reuters.com/article/factcheck-covid-vaccines-idU...

They have filed for full authorization for a reason. These vaccines have enough data backing their safety for full approval.

Re: Pfizer and Moderna vaccines may produce lasting immunity

#218
post #156

Earlier quoted context omitted.

It's not novel, this technology has been trialed and used for a decade, 3 years in vaccines. We do already have long-term data. You would see side effects for a vaccine within six months, and we have been administering it for much longer than that. The vaccines are safe. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7956899/

This is incredibly misleading. I used to be a close follower of the pharma industry, and you're making it seem like FDA trials happen on molecules and formulations somewhat related to the proposed formulation and then are, like, transitively approved on that hand-wavey basis. This is totally wrong. For reasons that should be obvious to any engineer that's worked on any kind of even moderately complex system, the mole…

Even if true, this novel molecule is not floating around in a body for an entire year waiting to have some side effect. They've been shooting it into people for a year and a half now. If there was something to worry about, it would have been seen.

But there are many parts of this vaccine that is shared with previous ones and the mechanics have been tested thoroughly. The science is the same. There's just no credible reason for those with normal immune systems to delay.

"This can't have happened for this yet. The trials are still underway. Unknown risk."

That's just simply untrue. The trials completed. Read the link.

Re: Pfizer and Moderna vaccines may produce lasting immunity

#219

Earlier quoted context omitted.

No it's not. Not in the United States lol, unless you work at some hospitals. Get vaccinated and wear a mask to avoid the Delta strain and stay at home more. You don't need to know someone else's status when you've got your own protection. Whenever someone tries to justify something with "but the collective" alarm bells should really start going off. You know that in Florida and other states where there are no mandat…

Masks do not provide as much protection for the users as for other people. I have a right to use public spaces.

I never understood this logic.

The material on both sides of the mask are the same, no? A mask can prevent a virus from leaving your nose/mouth but not enter?

Re: Pfizer and Moderna vaccines may produce lasting immunity

#220
post #156

Earlier quoted context omitted.

As a Canadian who emigrated to the US, the attitude you so proudly display--ostracizing people who aren't convinced of a novel vaccine with zero long-term safety information--makes me so happy I live here.

It's not novel, this technology has been trialed and used for a decade, 3 years in vaccines. We do already have long-term data. You would see side effects for a vaccine within six months, and we have been administering it for much longer than that. The vaccines are safe. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7956899/

> The vaccines are safe.

This is true by medicinal standards, but it's also a sleight-of-hand. The AstraZeneca vaccine had a rare side-effect that was right on track to kill more young women in Europe than the virus itself. That's why it was banned. By that standard, I could argue the viral infection is also safe - for young women at least.

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