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Pfizer submits Covid vaccine to FDA for approval, to distribute in December

pfizer.com

211–220 of 446 posts

Re: Pfizer submits Covid vaccine to FDA for approval, to distribute in December

#211

Earlier quoted context omitted.

Too late for that - the beta testers have already found it good. A phase 3 trial is beta test.

I'll let you test it for me and find out what the long term effects are.

I’ll let you know the long term effects of the vaccine, and you can let me know the long term effects of Covid-19.

Re: Pfizer submits Covid vaccine to FDA for approval, to distribute in December

#212

Earlier quoted context omitted.

I'll let you test it for me and find out what the long term effects are.

You should balance that against your chance of contracting COVID-19, and the unknown long term effects of COVID-19. For me, the long-term consequences of the vaccine seem to be better understood (theoretically, not empirically) than the long-term consequences of a COVID-19 infection.

I think "we" -- as a society -- should balance those two sides. Vaccinations do not always make sense at an individual level, but make a lot of sense at a societal level. If everyone was making a personal trade-off we would not reach the global maxima.

Re: Pfizer submits Covid vaccine to FDA for approval, to distribute in December

#213

Earlier quoted context omitted.

If the enemy is charging my base and someone offers me armor I'm not going to wait for all my fellow soldiers to try it out and see what happens.

Sounds like a reasonable position, until you extend the analogy: there is a slight, but nonetheless real chance that said armor has seriously adverse health effects on you. Maybe it spontaneously grows spikes and punctures your insides. Additionally, you also have, as an individual, the option to just stand further back in the line. You don't have to get in immediate contact with the enemy, you can just go to the bac…

Still, parents analogy seemed flawed so I tried to extend it.

All analogies are flawed. That's why they are merely suggestive and not meant to be interpreted overly literally.

Re: Pfizer submits Covid vaccine to FDA for approval, to distribute in December

#214
post #103
post #29

Well just like I don't immediately update to the latest OS I think I'll wait for the beta testing to happen :)

Few key facts: • In the entire history of vaccines, only one has been recalled because the vaccine itself caused long term side effects (a rotavirus vaccine that had rare complications and no deaths for those under 1yr). If you can't find any papers about it, that's why. It's like finding a paper on death by lava lamp explosions. It's happened ( https://www.latimes.com/archives/la-xpm-2004-dec-01-na-brief... .), but…

>You can read the list of recalled vaccines and why they were recalled straight from the FDA (https://www.cdc.gov/vaccinesafety/concerns/concerns-history....).

To be fair, it's really hard to compare this to anything that has existed before. mRNA vaccines are a whole new class of drugs that have never been approved for human use. This will be a world first when Pfizer gets the EUA next month.

Re: Pfizer submits Covid vaccine to FDA for approval, to distribute in December

#215

Earlier quoted context omitted.

I'll let you test it for me and find out what the long term effects are.

You should balance that against your chance of contracting COVID-19, and the unknown long term effects of COVID-19. For me, the long-term consequences of the vaccine seem to be better understood (theoretically, not empirically) than the long-term consequences of a COVID-19 infection.

how can the long term consequences of the vaccine be better understood than the virus? The vaccine is younger than the virus, and orders of magnitude of more people have had the virus.

Re: Pfizer submits Covid vaccine to FDA for approval, to distribute in December

#217

Earlier quoted context omitted.

* the vaccine is not 100% effective * we don’t yet know whether the vaccine prevents transmission. You can probably be a carrier and spreader even if vaccinated Those two facts alone mean we’re going to be wearing masks for quite some time, things won’t go back to normal for a while, and people are justified in being upset with others who refuse to protect everyone around them.

If we don’t even know a basic facts about the vaccine (whether people vaccinated can still transmit, how long it lasts), isn’t it natural for people too feel concerned about what else we don’t know ? Seems to be a few unknowns still ?

It’s natural for people to want perfect certainty before making health care decisions. That’s why public health policy exists: because there is never perfect certainty in vaccination, and yet we’ll be required to all the same.

Re: Pfizer submits Covid vaccine to FDA for approval, to distribute in December

#218

Earlier quoted context omitted.

It also depends on the known safety profile. With AstraZeneca some people already have to take pain medications after taking the vaccine...I wouldn't be comfortable putting using that vaccine without much wider testing. Fortunately I don't need to though, because soon we'll probably have 2 great vaccines to choose from.

> Fortunately I don't need to though, because soon we'll probably have 2 great vaccines to choose from. Indeed! And I'll be going with the adenoviral route which has been used for more than fifty years, rather than the brand new, first time ever mRNA product.

>Indeed! And I'll be going with the adenoviral route which has been used for more than fifty years, rather than the brand new, first time ever mRNA product.

Interesting, I feel the exact opposite. I can't wait to take a mRNA vaccine, but the adenovirus ones seem sketchy given that Sinovac, J&J, and AstraZeneca have all seen serious adverse events in their trials, while Pfizer and Moderna have seen none, along with much higher efficacy.

I wasn't aware there were any adenoviral vaccinations approved for human use? What are you referring to?

Re: Pfizer submits Covid vaccine to FDA for approval, to distribute in December

#219
post #176

How would one explain to a Facebook addict why they should get the vaccine and that it's not a Bill Gates/NWO conspiracy to sterilise them?

I would start by convincing them to get off of Facebook... the massive improvements to mental health one would see from that step alone would be amazing. In a way, I kinda hope the Section 230 debate does cause FB and Twitter to go dark for a few weeks... we could actually start talking to real humans without a computer in the middle!

Re: Pfizer submits Covid vaccine to FDA for approval, to distribute in December

#220

Earlier quoted context omitted.

You should balance that against your chance of contracting COVID-19, and the unknown long term effects of COVID-19. For me, the long-term consequences of the vaccine seem to be better understood (theoretically, not empirically) than the long-term consequences of a COVID-19 infection.

how can the long term consequences of the vaccine be better understood than the virus? The vaccine is younger than the virus, and orders of magnitude of more people have had the virus.

mRNA vaccines were understood and studied prior to Covid. Covid infections (still) are not understood.
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