I think that in the long run you'll see a hybrid ARM/x64 Mac sharing the same case in the same way we have hybrid graphics. If you look at most of the processes running on a Mac, how many of those need to be running on the power-hungrier Intel chip? You could easily offload much of the kernel, Dock, compositor, Twitter desktop, etc to a lower-power ARM. In the case where you aren't running any x64 apps, you could the…
This sounds incredibly kludgey and at odds with Apple's de-investment in macOS. (As in "reduced investment", not "divestment".) Adding massive complexity to eke out another hour or two of battery life seems like a poor choice when there are so many things to be fixed in the OS.
But a heterogenous CPU certainly does make sense. A super efficient, but not particular fast core for specific tasks that are more or less always running, and the beefy full core for regular work. If it eeks out another 2 hours of battery life, I can see Apple doing it when they're redoing a CPU from the ground up.