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Acetaminophen vs. ibuprofen

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Re: Acetaminophen vs. ibuprofen

#201

Earlier quoted context omitted.

If there's one thing I'm hopeful for regarding all this AI hype, it's that some day we might actually get the Expert Systems we were promised decades ago. Then, finally, we can stop expecting human doctors to know everything . There's just so much going on inside our bodies and it's unrealistic. I had a relative with a different story in the same theme. It sucks and I want to see this technology do something truly be…

The expert system relies on training data, and most of the medical data on the internet is either outdated or outright wrong. AI is not going to solve what the existence of Google hasn't solved already.

[dead]

Re: Acetaminophen vs. ibuprofen

#202
post #52

Earlier quoted context omitted.

I have taken 4-5g in a day while suffering from intense pain before. There is a limit to the amount of opioids they will prescribe you, even if you are in mind shattering pain. For instance while attempting to get your dental insurance to actually cover a treatment you may find yourself between risking organ damage or risking $5000+ in ER visit bills only to have them refuse to give you anything but Tramadol.

Whenever people here mention to my critique of US healthcare how its now mostly solved problem now, its 'good' to see the other side and reality. It certainly doesn't seem solved unless you have a million or two just laying around on the account, while mortgages and kids tuitions are paid. And I can easily imagine a long term condition or 10 which, if unlucky in terms of treatment cost coverage can wipe out that sum…

> Whenever people here mention to my critique of US healthcare how its now mostly solved problem now

Who says that? I don't think anyone sane can believe that US healthcare is "solved".

Re: Acetaminophen vs. ibuprofen

#203

> But if acetaminophen is safer, then why don’t official sources tell you that? Guess it depends on country. Here in Norway official sources[1][2] do say acetaminophen (paracetamol here) should be the default for treating fever and pain in kids, adults, pregnant women and elderly, and have for some time. Ibuprofen they say should be used with caution. [1]: https://www.dmp.no/nyheter/behov-for-smertestillende-slik-ve.…

Really? I get headaches semi-frequently and my first line of defense is ibuprofen, I use acetaminophen sporadically as a last resort

I take both. 500-1000mg acetaminophen, 200-400mg ibuprofen. Usually helps for headaches which I get frequently. I only take them for the worst headaches though, so probably once every couple of weeks on average.

Re: Acetaminophen vs. ibuprofen

#204

It's a very strange cultural thing too, Australians (and I presume other Commonwealth countries) default to paracetamol (acetaminophen) before ibuprofen Paracetemol has always been seen as first thing you'd take for pain relief, and you'd "step up" ibuprofen as an escalation, but that might more to do with marketing of Panadol (paracetemol) vs Nurofen (ibuprofen). We'd look on at the US where you were taking Advil li…

> Australians (and I presume other Commonwealth countries) default to paracetamol

The same is the case in the Netherlands.

Re: Acetaminophen vs. ibuprofen

#205

I lived with an ICU nurse for years and one of the things he emphasized was the risk of acetaminophen overdose. He's more than once treated the liver failure (and death) from it and by his words, it's one of the worse ways to go. The positive of it is it got me in the habit of logging whenever I take it, either in a note on my phone or just a sheet of paper I place on my dresser under the bottle. This helps make sure…

In mozambique i was committed to the hospital with my liver failing after spending two weeks taking acetaminophen daily because everyone at work got sick and someone had to keep the business up (it was a bank, our IT department was very specific and only 6 people knew that job and everyone got extremely hill). After two weeks, i finally went to the hospital and I couldn't leave; spent the next two weeks fighting for…

That sounds terrible! Glad you made it out alive and hopefully recovered well! Out of curiosity: how much did you take per day?

Re: Acetaminophen vs. ibuprofen

#207
post #17

Really lovely article. In paramedicine we usually treat 10g of acetaminophen in a 24-hour window as a potentially fatal overdose. That's also why the law in Australia was changed to require acetaminophen to come in blister packs (harder to get each pill out) of no more than 16. At 500 mg, that only gets you up to 8 g if you eat the whole thing, which is still hopefully non-fatal. I always thought a simple over-the-co…

NAC is so amazing for us in terribly polluted areas. Also great before drinking

Glycine + NAC even better, both precursors for Glutathione, Glycine also great for sleeping.

Re: Acetaminophen vs. ibuprofen

#208

Earlier quoted context omitted.

It’s the same in the UK - paracetamol is the default. Ibuprofen is better for reducing swelling, inflammation etc.

Ibuprofen is better are reducing fever and managing headaches. Paracetamol is the safer version Phenacetin. You used to be able to buy aspirin, phenacetin and caffeine..but phenacetin with withdrawn. APC when it was marketed was very popular but soon you were told to never give children aspirin for a fever so we used Paracetamol. Then Phenacetin was withdrawn and paracetamol became part of APC (like Alka selzta XS ,…

Wiki for phenacetin says it's mechanism of action is being metabolized into paracetamol. IDK about your "nowhere as effective".

It was withdrawn for sometimes being metabolized into another, toxic and carcenogenic, molecule.

Re: Acetaminophen vs. ibuprofen

#209
post #197

Earlier quoted context omitted.

NAC taken before consuming alcohol has a positive effect apparently, but taken afterwards it's detrimental as mentioned here: https://en.wikipedia.org/wiki/Acetylcysteine

Vaccine Ordering https://xkcd.com/2422/

Took me a while, because i pronounce "Pfizer" as "pfee-tseh-r" in my head

Re: Acetaminophen vs. ibuprofen

#210

Earlier quoted context omitted.

It’s the same in the UK - paracetamol is the default. Ibuprofen is better for reducing swelling, inflammation etc.

Ibuprofen is better are reducing fever and managing headaches. Paracetamol is the safer version Phenacetin. You used to be able to buy aspirin, phenacetin and caffeine..but phenacetin with withdrawn. APC when it was marketed was very popular but soon you were told to never give children aspirin for a fever so we used Paracetamol. Then Phenacetin was withdrawn and paracetamol became part of APC (like Alka selzta XS ,…

Interesting.

I guess it tracks with personal experience. I find Paracetamol is OK for fevers/generic cold symptoms but absolutely useless for a headache, Ibuprofen is the only thing that shifts them.

Well it's the only thing that shifts them now I'm in a country where I can't buy soluble aspirin and codeine OTC.

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