Sleep apnea pill shows striking success in large clinical trial

Post by mywrathacademia » Tue, May 27, 2025, 11:51 AM UTC

elric wrote: post #109

Llamamoe wrote: post #98

Earlier quoted context omitted.

The problem with CPAP is that 40% of patients don't tolerate it even for the 4h/night defined as treatment compliance, while most of the rest use it less than the full duration of the night, with studies demonstrating that treatment compliance depends on efficacy. And this is for traditional OSA in men - people with Upper Airway Resistance Syndrome(mostly identical mechanism as OSA, less oxygen desaturation, more aro…

I will keep beating this horse to death, but the vast majority of those who cannot tolerate CPAP are improperly titrated and/or have a mask that isn't right for them and/or are having leaks. Often all of the above. That 4 hours is just another symptom of a medical establishment that's not interested in treating patients, but is only interested in numbers. If you want maximum benefits from CPAP, you have to wear it al…

Post by mywrathacademia » Tue, May 27, 2025, 12:04 PM UTC

12_throw_away wrote: post #150

evanjrowley wrote: post #82

I must be in the minority of CPAP users who would use it even if I stopped having OSA. Why? A few reasons: 1. Sometimes I hardly notice it. Newer models are very quiet and portable. I'd even go as far as saying the mask is comfortable to wear, like a security blanket for the face. 2. Practically nothing filters out dust and cat hair better than my CPAP. An N95 mask might do better, but would be ridiculously uncomfort…

Yep - my first 4 weeks, I just hated the feeling of air getting forced into my airways. And then 2 weeks ago, it flipped on a dime ... I guess my brain decided "this is what sleepy-time breathing feels like", and now it's a very relaxing sensation. It all makes some sense, I think - it would be bad, evolutionarily, if we couldn't get used to the sensation of breathing , even if it happens to be slightly weird for wha…

Post by evanjrowley » Tue, May 27, 2025, 12:11 PM UTC

TMWNN wrote: post #156

evanjrowley wrote: post #82

I must be in the minority of CPAP users who would use it even if I stopped having OSA. Why? A few reasons: 1. Sometimes I hardly notice it. Newer models are very quiet and portable. I'd even go as far as saying the mask is comfortable to wear, like a security blanket for the face. 2. Practically nothing filters out dust and cat hair better than my CPAP. An N95 mask might do better, but would be ridiculously uncomfort…

I wouldn't use it without sleep apnea because of the annoyance with the hose. But I agree that otherwise my nasal mask is hardly noticeable.

Post by iamjackg » Tue, May 27, 2025, 12:29 PM UTC

mywrathacademia wrote: post #203

12_throw_away wrote: post #150

Earlier quoted context omitted.

Yep - my first 4 weeks, I just hated the feeling of air getting forced into my airways. And then 2 weeks ago, it flipped on a dime ... I guess my brain decided "this is what sleepy-time breathing feels like", and now it's a very relaxing sensation. It all makes some sense, I think - it would be bad, evolutionarily, if we couldn't get used to the sensation of breathing , even if it happens to be slightly weird for wha…

Sounds like a side effect of cpap is addiction? Does it cure sleep apnea or do you have to use it forever?

Post by bigjimmyk3 » Tue, May 27, 2025, 2:15 PM UTC

justinator wrote: post #146

Llamamoe wrote: post #97

Earlier quoted context omitted.

You're right, and Inspiratory Muscle Training is an easier alternative to playing didgeridoo, and it's very important to mention Mandibular Advancement Devices and soft cervical collars(since neck-jaw position matters, this is a big part of why apnea is worse on your back), but the thing is- it's unlikely to be enough. Ultimately, to REALLY fix Sleep Disordered Breathing, usually you want maxillomandibular advancemen…

>usually you want maxillomandibular advancement Yeah that's the ticket. I use a mouth retainer for this, but I've found more often than not these days that it comes out sometime during the night. I may look into these exercise to supplement.