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Heavy marijuana use increases schizophrenia in men, study finds

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Re: Heavy marijuana use increases schizophrenia in men, study finds

#201
I thought that marijuana interfered with sleep, and you just didn't get your proper REM sleep.

So if you continue it - REM sleep deprivation has side effects.

and if you stop it - your body will try to make up for lost time (REM) and make you hallucinate a lot.

maybe all of this is related to schizophrenia

Re: Heavy marijuana use increases schizophrenia in men, study finds

#202

Earlier quoted context omitted.

I'm very much for individual freedom when it comes to drug use, assuming you aren't hurting others. I think in the push for cannabis legalization, many people have forgotten that cannabis is a psychedelic drug. While it's not the same as LSD or psilocybin, it can definitely change perception and thinking. In 1996 I had a psychotic episode from LSD, and developed generalized anxiety disorder and panic disorder. I alwa…

> I firmly believe that psychedelics are triggers and not the cause of mental disorders If a neurotoxic drug such as cannabis causes psychosis in someone who would otherwise never have become psychotic without the drug, then whether you call it a cause or a trigger is quibbling over semantics.

Sorry, neurotoxic?

That's not a settled debate; not remotely.

There are many reasons to believe cannabis is neuroprotective. Especially when using safe, high CBD, high cannabinoid varieties; a rather vital distinction.

And it's not semantics, because you can't make the assumption that people would "never have become psychotic without the drug". On a population scale, such an effect would have stood out by now if it had much strength at all.

Re: Heavy marijuana use increases schizophrenia in men, study finds

#203
post #77

I find that weed's effects just heighten a person's extremes. I become slow, almost indecisively slow on the stuff. It does calm my ADHD slightly, but it also helps me sleep. I also only use the stuff at night, generally an hour or two before bed and after all my needs are taken care of. It turns my neurotic brother into a short-tempered asshole. He uses the stuff several times daily. Guess people react differently t…

Have you looked into ADHD and cannabis? The TLDR from my reading is that it actually improves your focus and lessens symptoms BUT those improvements also come with the downside of getting stoned.

This is not my experience. I find that weed makes my mind wander randomly down all sorts of tracks. Sometimes this can be fun, interesting, and insightful, but it's certainly not a state that helps my already very poor focus.

Re: Heavy marijuana use increases schizophrenia in men, study finds

#204

Earlier quoted context omitted.

> Autistic adults have significantly low blood serum levels of AEA. Autistic people’s neurons prune slower. Schizophrenic people’s neurons prune faster. These are all group-level findings, meaning they aren't true for every individual. You can do a study and find that there is a statistically significant difference in mean X between two samples – autistic vs control or schizophrenic vs control. But pretty much always…

You know whats really interesting? Autism and Schizophrenia used to refer to the same condition. The term "autism" was invented by Bleuler, who worked with Freud, as a shortened version of his "autoerotism" and referred to a state where a patient was totally absorbed in their own fantasies to the point of hallucinating them. This becomes clear if you look at Jung's "introvert/extrovert" dichotomy (Jung, who worked in…

> (Hans Asperger famously used Autism diagnoses to euthanize children, that's who "Asperger's Syndrome" is named after!)

Asperger was assigned to identify autistic children for exterminatiom, but mafe the case that certain ones were useful to the Reich, which is why “Asperger’s Syndrome” became the name for the manifestation of autism that was seen as a leader impairmemt.

Re: Heavy marijuana use increases schizophrenia in men, study finds

#205

Can we please stop making marijuana so strong. I already cut my marijuana with 50% CBD, and that's still plenty strong that I only need a single hit to be plenty high. I can't for the life of me understand why there's a race to the highest imaginable THC percentage, when it so clearly has an adverse effect on the experience.

100% agree. I think that the industry as a whole really optimized for the wrong thing for a very long time. It seems like in legal states, there's been a move towards more balanced strains (or at least, those have a niche in the market), but it seems like everyone was going for 30% THC by weight, and as little CBD as possible.

The "mids" I used to smoke back in my teenage years gave a better (read: more fun and relaxing) high than most of the "dank" weed I've smoked as an adult.

Re: Heavy marijuana use increases schizophrenia in men, study finds

#206

You have these cells in your brain called Microglia. They are responsible for cleaning up neurons and plaques and other weird proteins. These Microglia are activated by the firing neurons which release 2-AG and AEA (Anadamide). AEA binds to the CB1 receptor in these Microglia. 2-AG binds to CB2. THC binds to CB1. CBD binds to CB2. Autistic adults have significantly low blood serum levels of AEA. Autistic people’s neu…

So Schizophrenia is the opposite of Autism?

Some studies find that "schizophrenia runs in lower average IQ families, autism runs in higher average IQ families", from which some suggest that the autism-vs-schizophrenia distinction is grounded in a higher-vs-lower IQ distinction – see e.g. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4927579/ – but I think that kind of research is very speculative and needs to be taken with a large grain of salt

Other researchers suggest the boundary between autism and schizophrenia is weaker than is commonly supposed. Common diagnostic tests for ASD perform poorly in distinguishing it from schizophrenia; there is heightened prevalence of each condition among those diagnosed with the other; autism started out as a new name for childhood-onset schizophrenia (in fact the word "autistic" was originally coined to describe schizophrenia), and there is still a lot of dispute about what is the difference between autism and childhood-onset schizophrenia (the former is much more common than the later–subclinical hallucinations are common in children, but clinically significant psychotic symptoms are quite rare)

Nobody really knows, not even the experts.

Re: Heavy marijuana use increases schizophrenia in men, study finds

#207

I used to smoke in high school and college and it was great, no negative effects. Then I took maybe a half year break at 21. When I smoked again I would get super anxious and paranoid. To the point where I just needed to go lay in bed and wait it out. I thought I smoked too much or it was stronger than what I was used to. Took it a bit easier the next time. Same thing. I stuck to methylone, ketamine, methoxetamine, 2…

I spent several years in my early 20s as a daily smoker, but at some point in the last few years, I crossed some sort of line, and I seemingly can't smoke at all anymore without winding up anxious as hell. Ultimately this led to me just totally giving the stuff up, which isn't the worst outcome. I still miss certain aspects of it, but after consistently having bad experiences for a while, it seems that I'm just better off without it.

I don't really drink either, so my vices now are limited to vaping and a very occasional small dose of mushrooms.

/shrug, worse problems to have I guess.

Re: Heavy marijuana use increases schizophrenia in men, study finds

#208

Earlier quoted context omitted.

You know whats really interesting? Autism and Schizophrenia used to refer to the same condition. The term "autism" was invented by Bleuler, who worked with Freud, as a shortened version of his "autoerotism" and referred to a state where a patient was totally absorbed in their own fantasies to the point of hallucinating them. This becomes clear if you look at Jung's "introvert/extrovert" dichotomy (Jung, who worked in…

> (Hans Asperger famously used Autism diagnoses to euthanize children, that's who "Asperger's Syndrome" is named after!) Asperger was assigned to identify autistic children for exterminatiom, but mafe the case that certain ones were useful to the Reich, which is why “Asperger’s Syndrome” became the name for the manifestation of autism that was seen as a leader impairmemt.

He wasn't assigned to identify "autistic children" specifically for extermination. Hans Asperger was a psychiatrist. Psychiatrists in Nazi Germany (post-Anschluss Austria in his case) were expected to evaluate all of their patients for potential extermination, children included. Some psychiatrists refused to cooperate with the regime, at great personal cost to themselves. Other psychiatrists signed up to become enthusiastic members of the Nazi Party. Asperger chose a middle path – he chose not to join the NSDAP, but he joined some of their affiliated organisations; he chose to cooperate with the regime, and be supportive of it–not in an overly enthusiastic way, but with sufficient enthusiasm to ensure his Nazi superiors would not stand in the way of his career advancement.

He did successfully argue that some more intelligent children should be spared, on the grounds they had unique skills which could be valuable to the regime. However, less intelligent children, he was happy to refer to be murdered (in most cases without the knowledge or consent of their parents). He wasn't evil in the way in which many devout Nazis were, just in the more banal way of the many who collaborated in the regime's crimes out of personal self-interest, or through coming to believe its propaganda.

Re: Heavy marijuana use increases schizophrenia in men, study finds

#209

You have these cells in your brain called Microglia. They are responsible for cleaning up neurons and plaques and other weird proteins. These Microglia are activated by the firing neurons which release 2-AG and AEA (Anadamide). AEA binds to the CB1 receptor in these Microglia. 2-AG binds to CB2. THC binds to CB1. CBD binds to CB2. Autistic adults have significantly low blood serum levels of AEA. Autistic people’s neu…

So Schizophrenia is the opposite of Autism?

Just gotta find the perfect balance between the two

Re: Heavy marijuana use increases schizophrenia in men, study finds

#210
PSA: With regard to psychosis, there's a big difference between high THC cannabis and high CBD cannabis.

Huge.

If you are one of the many who comment with confidence on this issue, but are not aware of the distinction, please consider looking into it.

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