Everyone is different, but personally I won’t buy a keyboard without separate Delete and Backspace keys, without Home/End/PgUp/PgDn/Insert keys, and without a dedicated Menu key [0], for any kind of serious work. I’d also imagine that one is prone to bump into the rotary knob if one is not fully conditioned to that keyboard. I applaud the T-shaped cursor block and the full-sized function keys, although it would be us…
My laptop has Home/End/PgUp/PgDn as the Fn function on the Arrow keys, and its actually really good. So good I've actually setup other machines with the same shortcuts wherever I can.