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Modern city dwellers have lost about half their gut microbes

science.org

201–210 of 318 posts

Re: Modern city dwellers have lost about half their gut microbes

#201

Can someone comment on the effect of chlorinated town water on gut microbes? Would treated water have an affect as opposed to consuming rain or bore water?

> effect of chlorinated town water on gut microbes

Unless you are drinking a tap water (pretty extreme thing to do!), the effect is probably non-existing:

https://cooking.stackexchange.com/q/67027

Re: Modern city dwellers have lost about half their gut microbes

#202
post #198

Earlier quoted context omitted.

> indicating the importance of preserving this treasure of microbial diversity from ancient rural communities worldwide This study (and the FA) mention losing/presrving microbial diversity, but don't touch on how we got these microbes in the first place. I was expecting it comes mostly from what we eat and the environment, including eventually the people around us (and the mother - baby link ?) I kinda wondered if we…

Very likely. Almost all probiotics people take are transient. Meaning they just pass through and don't form long term colonies in our guts. There's a few exceptions with some soil-derived probiotics but those are also the least predictable It seems really likely to me that our bodies have likely adapted to an environment where exposure to certain types of bacteria is very common. For example, there's been a lot of re…

Interesting, I discovered once that soil on my socks could make them not smell. I don’t know if the specific soil mattered though, and the circumstances for my discovery were never replicated.

Re: Modern city dwellers have lost about half their gut microbes

#203
post #190
post #45

Pretty much every culture around the world 100 years ago had some staple fermented food. Nowadays, a lot of people in western culture at least outright refuse yogurt or other fermented foods like saurkraut or pickled cabbage that used to be staples in these people's ancestor's diets a few generations ago. People are becoming even lactose intolerant. You have to fertilize your microbes so to speak and eat these sorts…

Zero added sweetener, straight Greek yoghurt. Absolutely sublime. To the typical North American diet it tastes incredibly foreign because the US of A is drenched in sweeteners. But unsweetened foods just taste beautiful once you get used to them.

I spent two months in Turkey and can confirm this. The national drink is called Ayran, and it’s not only fantastic tasting and cheap but full of nutrition.

Re: Modern city dwellers have lost about half their gut microbes

#204
post #175

Earlier quoted context omitted.

Whats scary is that we have more and more civilization diseases and we have no idea whats causing them beside guesses. Worsening of the environment we live in impacts us in ways we cannot even imagine. Scary is that we cannot go back, coz its financially impossible for most.

Cities were historically unhealthy, etc, etc, as well. Yet people kept moving to them. So "most people can't afford to [leave civiliation]" is far from new. Perhaps the life everyone has been fleeing to get to cities was never what you think it is for most.

The movement to cities was more likely the result of an arms race rather than preference. Most anthropological evidence points to deterioration in quality of life (e.g. diet, height, disease, teeth, inequality) when comparing hunter-gatherers and city dwellers.

Larger populations, specialization of labor, and fortifications made city-states militarily superior to small bands of hunter-gatherers and allowed cities to dominate a surrounding region (at least until the modern horse). When a region was depleted of wild game then cities and their croplands were the most reliable source of food. Armies from city states would not infrequently raid and capture smaller groups of humans and bring them back to cities as slaves.

So cities were likely a forced choice, as smaller nomadic groups were forceably absorbed into the domains of city-states or repelled toward less hospitable lands.

Re: Modern city dwellers have lost about half their gut microbes

#205
post #51

Earlier quoted context omitted.

chobani claims six strains of yogurts, I used that as starter for my homemade yogurt batches since then. Otherwise I try and get my exposure in from the environment. I'm vaccinated so I don't bother with the mask unless there are hard rules. I will avoid overusing hand sanitizer. I take crowded public transit and otherwise walk around sidewalks and stores with a bunch of people vs private car and delivery of all my n…

Is that beneficial if it's a busy area? There's some pollution that I want to simply avoid, primarily car exhaust and fine particles like tire dust.

You would be surprised. According to the EPA:

"In the last several years, a growing body of scientific evidence has indicated that the air within homes and other buildings can be more seriously polluted than the outdoor air in even the largest and most industrialized cities. Other research indicates that people spend approximately 90 percent of their time indoors. Thus, for many people, the risks to health may be greater due to exposure to air pollution indoors than outdoors."

https://www.epa.gov/indoor-air-quality-iaq/inside-story-guid...

Re: Modern city dwellers have lost about half their gut microbes

#206
post #175

Earlier quoted context omitted.

Whats scary is that we have more and more civilization diseases and we have no idea whats causing them beside guesses. Worsening of the environment we live in impacts us in ways we cannot even imagine. Scary is that we cannot go back, coz its financially impossible for most.

Which "civilization diseases"?

Diseases of civilization usually refers to things like diabetes, obesity, heart disease, cancer. I'm not 100% sure but I think the common threads are metabolic and inflammatory.

Re: Modern city dwellers have lost about half their gut microbes

#207
post #188
post #175

Earlier quoted context omitted.

Whats scary is that we have more and more civilization diseases and we have no idea whats causing them beside guesses. Worsening of the environment we live in impacts us in ways we cannot even imagine. Scary is that we cannot go back, coz its financially impossible for most.

> Whats scary is that we have more and more civilization diseases and we have no idea whats causing them beside guesses. We do have some good mechanistic hypotheses, but most reviews fail to describe them because a lot of research is hand wavy. However, things are slowly reaching mainstream. Let's consider type 1 diabetes (T1D), which is a common autoimmune disorder where beta cells in the pancreas get destroyed by y…

My understanding is that, in healthy humans, gut bacteria are not presented in huge numbers to the immune system because the intestinal barrier (tight junctions) prevent most of them from migrating into the blood stream.

Are then not antibodies against gut bacteria a clear sign of a damaged gut barrier?

(FWIW there seem to be suspicions that Ankylosing Spondylitis is also caused by a certain type of bacteria being present _and_ getting into places such that antibodies against them are formed.)

Re: Modern city dwellers have lost about half their gut microbes

#208
post #45

Pretty much every culture around the world 100 years ago had some staple fermented food. Nowadays, a lot of people in western culture at least outright refuse yogurt or other fermented foods like saurkraut or pickled cabbage that used to be staples in these people's ancestor's diets a few generations ago. People are becoming even lactose intolerant. You have to fertilize your microbes so to speak and eat these sorts…

Quoted post unavailable.

Are you conflating fluoride and chlorine? Or are you gulping water down your throat at swimming pools? If it's the latter then you really should stop doing that.

Re: Modern city dwellers have lost about half their gut microbes

#209
post #45

Pretty much every culture around the world 100 years ago had some staple fermented food. Nowadays, a lot of people in western culture at least outright refuse yogurt or other fermented foods like saurkraut or pickled cabbage that used to be staples in these people's ancestor's diets a few generations ago. People are becoming even lactose intolerant. You have to fertilize your microbes so to speak and eat these sorts…

Lactase persistence is regulated by genetic mutations, not gut microbes. The negative symptoms of lactose intolerance is exactly due to lactose being able to reach the gut and making the microbes there flourish by digesting lactose, creating large quantities of gas and other metabolic byproducts that cause flatulence, diarrhea, etc. People don't spontaneously become lactose intolerant just because they stopped eating…

> Lactase persistence is regulated by genetic mutations, not gut microbes.

> Koreans eat lots of fermented vegetables, yet why are 70%-100% of Koreans estimated to be lactose intolerant?

On the other hand, there is Mongolia:

> But a closer look at cultural practices around the world has challenged that picture. In modern Mongolia, for example, traditional herders get more than a third of their calories from dairy products. They milk seven kinds of mammals, yielding diverse cheeses, yogurts, and other fermented milk products, including alcohol made from mare's milk. “If you can milk it, they do in Mongolia,” Warinner says. And yet 95% of those people are lactose intolerant.

https://www.science.org/doi/10.1126/science.362.6415.626

Even though most products are fermented for shelf life, unfermented milk is widely consumed by Mongolians to this day.

Re: Modern city dwellers have lost about half their gut microbes

#210
post #161

This article is mostly cliche popsci trash that isn’t worth reading. Good for a game of logical fallacy bingo. The only interesting development seems to be the methodology but that only gets a passing mention. The rest is basically fearmongering. > In humans, for example, gut bacteria influence how the immune system responds to pathogens and allergens, or interact with the brain, affecting mood. Ok. But what does tha…

Why is it “scary”? Nothing in this article established any cause for concern. I think when people see a difference in modern life versus traditional, and that difference was unexpected and unintended, that in itself is cause for concern. I don't need to believe claims about how important the gut biome is to the brain etc. But I would be surprised if the there weren't some consequence of the difference, and it seems l…

You answered the wrong question. The article reproduced a claim without substantiation.

I didn’t conclude that the effects are benign. I claimed that this article does nothing to assist me in deciding if they are.

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