Earlier quoted context omitted.
You wouldn't imply that Signal had framed you. You would imply that someone else had framed you using the same vulnerabilities as Signal has now indicated exists. i.e. You can't trust Cellebrite because it's now known to be trivial to subvert their software. It's also difficult for Cellebrite to prove that there aren't remaining vulnerabilities in their software since Signal didn't disclose the problems they found an…
It depends on the standard of reliability required. A good defence legal team might use this to argue that the phone data wouldn't be sufficient evidence in the actual criminal proceedings, you do need to prove things beyond all reasonable doubt there; however, even with all these caveats it would be sufficient to use that phone data for investigative purposes and as probable cause for getting a warrant for something…
That’s not a guarantee, of course, and it could be possible for police to corroborate that you had contact with someone else in another way (through records from a wireless carrier or by doing shoe leather investigative work) and use try to get data on that person to get them to testify, but if their only link was through messages that had been deemed inadmissible, they can’t use that witness.
The more likely question in a scenario you describe would be if the compromised Signal data would be enough to raise questions about the validity of all the data on the device. I.e., if Signal is out, can they use information from WhatsApp or iMessage or whatever. Past case law would suggest that once compromised, all of the evidence from the device is compromised — but a judge might rule otherwise.
It would be cool if Signal or another app could use those exploits they’ve uncovered to inject randomized data into the data stores of other messaging applications too. You know. Just as an experiment.