Earlier quoted context omitted.
Why would it be troubling that there is more to learn? There is always more to learn. If you were under the misconception that we knew everything about the human body, then I’m glad you’re now enlightened
It's about expectations. We obviously will never know everything about anything. Some things seem easier to discover than others. This seems like something easy to discover that has long since gone undiscovered.
This report suggests that we do have 'streets' missing. Researchers are now delving into finely nuanced areas of research at a level the equivalent of the house before the preliminaries are resolved - before all streets are found. Bypassing prerequisites always has serious consequences, things go wrong, errors occur, time is wasted, work is duplicated by others, etc. Even patients may die.
I'd suggest that no one yet knows how this will impact research that's already been completed and which now has to be reinvestigated.