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Biohacking Lite

karpathy.github.io

201–210 of 370 posts

Re: Biohacking Lite

#201
post #95
post #90

Earlier quoted context omitted.

> There is nothing inherently wrong with "processed" food There's a distinction between processed and ultra-processed (or highly processed). For example, canned fish is processed (added salt and oil), while a frozen TV dinner is ultra-processed (many ingredients added, some of which you probably don't have in your kitchen). Processed food is fine assuming you're aware of what's in it, how it's processed, and make sur…

> There's a distinction between processed and ultra-processed (or highly processed). For example, canned fish is processed (added salt and oil), while a frozen TV dinner is ultra-processed (many ingredients added, some of which you probably don't have in your kitchen). Sure, but OP said ban all processed food. That's what I'm responding to, not "ban all ultra-processed food." That said, I do find your categorization…

Actually I do take issue with your example of grass-fed steak. Not sure why you would think it is not healthy, not even going to debate that. But do not dismiss it thinking the actual grass-feed has no impact. It increases the saturated of the meat of ruminants. If you want to go on a learning trip, look into the research made in the 40s about fattening cattle with saturated vs unsaturated fats.

I think it is a bit meaningless to talk about the merits or demerits of particular ingredients (other than the obviously bad such as rancid fats, pollution by heavy metals, or high in toxins) Humans evolved to eat a varied diet and the more variety of nutrient dense food you have the better off you will be. The main issue with nutrition is how can we teach people to eat better while keeping the production costs down.

I recognize I'm bloody lucky to be able to afford the food I get to eat every week, but just thinking of the resources required to have everyone eat this way is very hard. How sustainable would it be for everyone to eat fresh seafood every weekend or constantly import oranges to northern latitudes? Part of the problem is that people choosing processed food leads to an increasing divide in costs between the processed and the freshly prepared, only due to economies of scale. And it will only keep getting worse. My parents' generation all had fresh milk delivered daily at their homes (relatively affordable even for the middle class), today how many people could afford something like that? It took only a little time when cheaper options appeared for it to become uneconomical and nowadays even if you wanted to pay a premium, how big would it be?

A big mistake is to only focus on macronutrients when micronutrients are as important. Even then, it is a relatively unexplored field, how many chemical species you think an apple has? We have explored relatively few classes and particular examples of vitamins and it would be misleading to just go by the RDA of a few classes of chemicals which were explored because of simplicity, technical development at the time? How many vitamin E analogues are in a kernel of wheat? When did we stop doing this basic research into food and nutrition? There are millions of different molecules in natural food, how much is destroyed by processing? Like the homogenization of milk, which is practically very vigorous stirring and yet it destroys lactoferrin.

Re: Biohacking Lite

#202

This is such beautiful work I’m speechless.

It's lot of technical details that basically proves the old adage "Eat Less, Exercise More" to see weight loss. He just did extensive tracking around it.

Re: Biohacking Lite

#203

Earlier quoted context omitted.

You don't develop type 2 diabetes from being fat, you develop diabetes from high average blood glucose levels triggering insulin resistance. Also, what is the pollution you are talking about? From what I understand, lipolysis generates ketones, which at normal lipolytic amounts aren't toxic. https://en.wikipedia.org/wiki/Type_2_diabetes?wprov=sfla1

> Also, what is the pollution you are talking about? For example reactive oxygen species. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1865572/

Oh I see now that I read your parent comment completely wrong, you are right. Sorry, thanks for the citation!

Re: Biohacking Lite

#204

Earlier quoted context omitted.

This is really interesting - I'd love to sit down and compare notes how we arrived at two completely different views of the food world. (It even holds for the "plain nuts" comment - I find it incredibly hard to get nuts that aren't roasted and/or salted)

> I find it incredibly hard to get nuts that aren't roasted and/or salted I don't see plain nuts as often as I'd like in stores, but they are super easy to find online: https://www.amazon.com/s?k=raw+almonds

Here's where Amazon's reputation for cheap fakes is biting them - I'm not risking food from them, since I can't fully trust the integrity of their goods.

But Trader Joe's usually has them too. Safeway sometimes does.

It's not that it's impossible, it's just that they don't have the same "staples" status they have in Europe. Usually, you find raw nuts in the cooking/baking ingredients area, while salted & roasted are considered "party food". And they're more likely to not have the party food variety than the raw variety.

Re: Biohacking Lite

#205
post #51

I'm French (and incidentally a doctor,and my post is not judgemental in any way, this is not the point). Everytime I travel to the USA, I'm puzzled by how difficult it is to "eat normally" (= by my own standards). You can find really good junk food everywhere, or pay a really high price to eat in high-level Italian restaurants for example, but it is very difficult to eat standard meat-with-vegetable-without-sugar-add…

> Everytime I travel to the USA, I'm puzzled by how difficult it is to "eat normally"

I'll second that, I've only been once for a few weeks on a work related trip, and I never paid attention to what I was eating but by the second week I felt run down, lathargic and really 'not great' - Hard to describe properly but I wasn't myself at all. With work I was connected with a doctor that I met because I just didn't feel 'right'.

I wasked asked the usual questions but after talking a bit more about my diet usually (even before mentioning what I was eating in the US) she knew exactly what was going on. My body wasn't used to breaking down the amounts of processed sugars that are more commonly found in everyday foods in the US.

I took a more concious approach to what was coming into my body and over a week I was able to feel normal again.

I come from Ireland, we have a diverse mix of foods available, you pick a country, I can tell you a street to find their food authentically and I love trying them. I also cook heavy with bad cholesterol, lots of butter thanks to French friends, lots of salt in other dishes from others, lots of cheese, cured meats, smoked cheeses and meats, snacks etc. - My diet was never interestingly good.

After my US trip I realised that there is a small poisoning in a sense being taken over the consumption.

> My 2 cents: - eat as much vegetables as you want (learn to cook them, with a little bit of olive oil)

I'm not stereotyping here, my exposure to the collegues from the local area never cooked. This is fine, but when you replace good food for fast food, you start to go into that chain. They didn't know a good way how to peel an avocado, which I found out on a drunken night with them in my apartment. 10+ and none of them knew how to prep an avocado. But that is not their fault at all..

> It looks like this is hard to do in the USA

Spot on. I cannot stress this point enough. You have to go out of your way to eat even moderately health conscious. This is a real shame. We will all take the easier path : 'Ah tonight I'll just get take-away, I'll just grab something on the way home.'

I grew up as a kid in Italy until I was 12, probably the only thing that I too away from it as a positive was that preparing, cooking and eating food is really not for sustenance.

Sustenance is the result, what matters is the social time, the prep is almost like a meditation, and the collaborative effort is like a social movement.

Food is really not just for sustenance. And I implore anyone reading this to try just cook a meal with friends, family or loved ones. It has a nice impact on way more than your sustenance intake.

Sugar is good, avocadoes have a lot of them, even the bad ones, but I would much prefer to enjoy my food than inhale it, in the US, it was seen as a time consumer.

'You are what you eat' - This expression didn't come from nowhere.

PS: 5 a day and the Pyramid might be wrong, there is no 1 scale for everyone. But there sure as shit isn't a cereal loaded with sugar for anyone.

What really annoyed me though, was the cost of it. To eat more natural, is more expensive than processing food. Odd.

Re: Biohacking Lite

#206
post #192
post #187

Earlier quoted context omitted.

So... where can a non-PT find this kind of advice? Maybe you, or any other trainer you can recommend? Or some online resource? (Personally, I'm probably above-average knowledgeable about fitness, but I still find the information unmanageably overwhelming - train every day, every 3 days, every muscle once a week, every muscle 3 times a week, big muscles less often than small muscles, focus on strength, focus on growth…

You probably need to be more specific about your end goal. Is it to lift a particular amount, run a marathon, climb a certain route etc? There are usually specific trainers for certain skills, just like in video games :) If I wanted to get better at bouldering, I'd book a 1 on 1 at my climbing wall, not a generic trainer at the local gym (but maybe I would after advice from the climbing coach). For generic "get fit"…

I agree there's a lot of conflicting information and that specificity is key. But it can also be useful to have a guide for when you change goals, someone who knows your history and preferences etc.

Body composition changes typically go through multiple different phases and cycles. It might seem like you'd want someone specific for each phase, yet some consistency is helpful across phases too. As an analogy, you wouldn't want to change universities for each year of your degree

Re: Biohacking Lite

#207
post #51

I'm French (and incidentally a doctor,and my post is not judgemental in any way, this is not the point). Everytime I travel to the USA, I'm puzzled by how difficult it is to "eat normally" (= by my own standards). You can find really good junk food everywhere, or pay a really high price to eat in high-level Italian restaurants for example, but it is very difficult to eat standard meat-with-vegetable-without-sugar-add…

Your opinion is balanced. But it'll appear as nonsense to Americans. Americans are ideologues. They love freedom. They like their own camps. They want to find eternal truths in everything. (There's no such thing).

In the dietary world, you'll find anti-sugar camps, anti-fat camps, Atkins diet, ketogenic diet, fitness buffs. This article is an example. It's a deep dive full of science. The conclusions, however, are mostly nonsense.

I'll eat like you suggest. But I'll entertain with the reading. :)

Re: Biohacking Lite

#208
post #131

Earlier quoted context omitted.

The general jab at the Americans. If I look at Europe food culture with a certain lens, I just see shitty doner kebab places in every corner and turkish grocery/meat stores that smell horrible. Obviously, that lens is cracked, tinted with biases. Some points are valid though. Honestly, as an American, we've got some awful vegetables and tasteless food just about everywhere unless fat/sugar is added to them. Probably…

I made clear I have no anti-american views (and I don't feel like US citizens, generally speaking, are so much more open to external opinions than Europeans by the way). The problem is not related to the quality of soil or to the borders but to the fact that we humans have a recent tendency to over-engineer a very natural process : eating simple, normal, things.

As an American, I absolutely agree with your original post. I find it so much more difficult to eat good food here unless I pay a ton of money. Good food is also usually the most inconvenient choice.

I also think that our obsession with work hurts us. We don't have time to slow down and cook.

Re: Biohacking Lite

#209
post #187

As a personal trainer I'm really impressed by the technical depth of this post, although it really only centers on the idea of caloric deficit, which is relatively basic compared to the other topics he mentioned. It's so hard to visualize small long-term biological changes without moving averages. "Trust the process" is so important. "Trust the algorithm" is even more apt: • what/when to eat, • what/when to train, an…

So... where can a non-PT find this kind of advice? Maybe you, or any other trainer you can recommend? Or some online resource? (Personally, I'm probably above-average knowledgeable about fitness, but I still find the information unmanageably overwhelming - train every day, every 3 days, every muscle once a week, every muscle 3 times a week, big muscles less often than small muscles, focus on strength, focus on growth…

Watch YouTube AthleanX Jeff Cavalier.

Eventually you'll have to learn through experimentation what works for you. Will take 5 to 10 years.

Re: Biohacking Lite

#210
post #51

I'm French (and incidentally a doctor,and my post is not judgemental in any way, this is not the point). Everytime I travel to the USA, I'm puzzled by how difficult it is to "eat normally" (= by my own standards). You can find really good junk food everywhere, or pay a really high price to eat in high-level Italian restaurants for example, but it is very difficult to eat standard meat-with-vegetable-without-sugar-add…

> I'm French ... I'm puzzled by how difficult it is to "eat normally"

This really needs so much attention and focus given the ungodly delicious amount of butter French people cook with.

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