#1 is probably require Journals to agree and publish research before the results are known based on the experimental design and require scientists to include there raw data. Preferably as they collect it. This is to counter: http://xkcd.com/882/

Require Journals to Publish the first 2 studies that try and reproduce a given result. Note: Publish need not mean include in the paper copy's just indexed and searchable online. This let's you create a reproducibility index which might not mean much until they have done a fair bit of research but still something there going to keep in mind.

Funding agency's would need to set aside a large amount to validate any study. However, as there is a lot of null results that the percentage is probably not all that high. More importantly as not doing so means the results are practically worthless in the first place it's still a good idea even if it takes 1/2 the overall budget.