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The Trump administration's Threat to Scientific Research

marginalrevolution.com

21–28 of 28 posts

Re: The Trump administration's Threat to Scientific Research

#21
post #2

there is one single person who is driving 99% of the damage Russell Vought everyone knows who Stephen Miller is but Russell Vought is the real monster for perspective, he got rid of the very programs that developed a drug to keep his child alive from a rare genetically inherited disease now you get what we are dealing with and here's the thing, Vance is the handpicked successor by Heritage Foundation so even if Trump…

The Republicans are either going to get absolutely shellacked, in which case a lot of this stuff is going to get rolled back, or we're going to end up with an autocracy, in which case shit is going to get much worse.

Rolling this stuff back doesn't instantly restart all of the science that was built up for decades. Nor does it get the smartest people back into the country after being kicked out or scared to stay.

Damage is done, we'll forever be behind, this isn't the place to go to research anymore.

Re: The Trump administration's Threat to Scientific Research

#22
post #17

Earlier quoted context omitted.

The Republicans are either going to get absolutely shellacked, in which case a lot of this stuff is going to get rolled back, or we're going to end up with an autocracy, in which case shit is going to get much worse.

they aren't going to get "shellacked" that would seem logical but it has nothing to do with logic this happened because 50% of latinos (natural born, naturalized) voted for the Orange Infant because THEY DONT CARE about anything else except they thought it would give them an economic edge and pull up the ladder behind them they aren't going to go vote Democratic this election, at best they might stay home because the…

> with full impeachment, Vance becomes President and that would be a NIGHTMARE even worse than what we have now

Vance has no popularity or support. Right now Trump is able to destroy the country because congress is doing nothing, and they're doing nothing because they're afraid of Trump. I don't think they'll be afraid of Vance.

Re: The Trump administration's Threat to Scientific Research

#23

Earlier quoted context omitted.

Lest anyone take this seriously - the above link is a case study of a single person who appears to have had Covid and other health issues for years. The authors in NO WAY establish that their detection of Covid spike proteins and immune response are due to vaccine injury, if you even believe any of their results. It's the science-ish equivalent of saying: my Uncle got a vaccination, then walked outside and was hit by…

[flagged]

Brandolini's law is strong in this one.

Let me pick one thing: their main (we-found-alien-life-level) claim that they detected vaccine-derived mRNA and non-functional fragments of the artificial plasmid DNA used in vaccine manufacturing in this person's circulating cells, 3+ years after vaccination. This DNA is supposed to be carefully filtered out BTW before packaging into vaccines, but OK, it's worth thinking about. This DNA would also be degraded quickly if injected - it's linearized before use, but OK let's say multiple processes failed somehow, and some voodoo magic keeps it from being gobbled up. Even they don't outright claim to know how it got there, because any concrete proposed mechanism would either sound extremely implausible or impossible - as it turns out it probably doesn't matter either way (see below.)

On p. 16 of the paper they claim to detect the actual vaccine mRNA only in exosomes. They could not detect it at all in peripheral blood mononuclear cells, where, even more extraordinarily they claim to have found and sequenced the ori1 and ori2 plasmid backbone used in Pfizer vaccine manufacturing (but crucially, none of the three spike protein sequences that would actually cause immune system problems if transcribed into a protein.) So I don't know what to make of the ori1/2 artifacts, except that I'd check that these sequences were truly unique to the Pfizer process (often these are conserved sequences that many labs use.) Even if they are somehow from the vaccine, and somehow active, they lack the spike sequences so would not produce mRNA in exosomes and thus spike proteins (so irrelevant to their other measurements of spike protein.)

So where do they think the mRNA in the exosomes come from? Well, if it ISN'T in the PBMC's (which it would be if it was being expressed there), then it has to be in "extracellular vessels" from the original injections. For 3+ years. At detectable concentrations. Mmmm hmmm. They could check this of course because the Pfizer vaccines use specially modified RNA's - that would be a smoking gun, but of course they didn't check this. You know why. You know where else one gets mRNA for spike proteins, that could end up in exosomes? Covid. Or maybe just a recent vaccine injection. Interestingly, they didn't bother to sequence the amplicons of the mRNA that they banded out on a gel - that also would be a pretty convincing indication it was from Pfizer, as any Covid in the wild today would have enough mutations to be identifiable. They did this exact thing for the ori1/2 bands, hmm I wonder why they didn't do this? You know why.

I could go on, but I have done enough public service for one morning.

Re: The Trump administration's Threat to Scientific Research

#25

Earlier quoted context omitted.

Lest anyone take this seriously - the above link is a case study of a single person who appears to have had Covid and other health issues for years. The authors in NO WAY establish that their detection of Covid spike proteins and immune response are due to vaccine injury, if you even believe any of their results. It's the science-ish equivalent of saying: my Uncle got a vaccination, then walked outside and was hit by…

[flagged]

Oh man the Earth is not flat enough to prevent "intelligent design" from leaking all over the place. This is the "diversity of thought" Russell Vought is bringing to our universities.

Re: The Trump administration's Threat to Scientific Research

#27

Earlier quoted context omitted.

[flagged]

Brandolini's law is strong in this one. Let me pick one thing: their main (we-found-alien-life-level) claim that they detected vaccine-derived mRNA and non-functional fragments of the artificial plasmid DNA used in vaccine manufacturing in this person's circulating cells, 3+ years after vaccination. This DNA is supposed to be carefully filtered out BTW before packaging into vaccines, but OK, it's worth thinking about…

So, there is material there but you are unsatisfied with the thoroughness related to brand identification and want a 99.95 confidence interval on discerning between natural disease vs toxoid injection.

It sounds like you believe that DNA contamination in the manufacturing process would leave the body rapidly and they are saying that it sits around in exosomes for much longer based on their observed specimen.

The latest science thus being that exosomes with DNA contaminants may not clear the body in the manner previously presumed.

It is highly likely that it was only presumed and nobody actually thoroughly analyzed it before. The science of how fast exosomes cleared was likely a speculation from years ago, and it may in fact be wrong now that someone has actually funded observing exosomes over the long term.

Therefore, this paper is cutting edge science and annoys the establishment because it attacks some sacred presumption upon which entire edifices are built. It attacks such presumptions with observable empirical facts. That makes one have to consider how many it would take to falsify a premise, a premise that they might realize was never hypothesis tested in the first place -- since it is in fact a speculated dogma instead of an observed scientific fact.

Re: The Trump administration's Threat to Scientific Research

#28

Earlier quoted context omitted.

Brandolini's law is strong in this one. Let me pick one thing: their main (we-found-alien-life-level) claim that they detected vaccine-derived mRNA and non-functional fragments of the artificial plasmid DNA used in vaccine manufacturing in this person's circulating cells, 3+ years after vaccination. This DNA is supposed to be carefully filtered out BTW before packaging into vaccines, but OK, it's worth thinking about…

So, there is material there but you are unsatisfied with the thoroughness related to brand identification and want a 99.95 confidence interval on discerning between natural disease vs toxoid injection. It sounds like you believe that DNA contamination in the manufacturing process would leave the body rapidly and they are saying that it sits around in exosomes for much longer based on their observed specimen. The late…

>It sounds like you believe that DNA contamination in the manufacturing process >would leave the body rapidly and they are saying that it sits around in >exosomes for much longer based on their observed specimen.

No. The ori1/2 sequence DNA is used in manufacturing, and what they claim to have found lacked spike protein sequences, so irrevelant other than a hand-wavy "hey something happened here." The mRNA (completely different thing) is in (exclusively) exosomes, which they heavily imply are from the vaccine (because the mRNA isn't found anywhere else, which it would be if some cells were creating spike proteins.) They give no mechanism for how the vaccine lipid containers last three years in the body, because any hand-wavy bullshit explanation would sound completely absurd, even they know this. BTW, the bands on their exosome mRNA gels are almost non-existent, making it all the more important they verify exactly what those amplicons are. NGS is extremely sensitive and they could have sequenced these very faint bands, to prove it was vaccine derived (which, again, they did for the ori1/2 bands.) Although, again, that DOES NOT prove the ori1/2 have been incorporated into replicating cells in the body, or come from the Pfizer vaccine, two more absolutely extraordinary claims.

Far from "cutting edge science", this paper is a great example of how people with an agenda can overlook basic science questions to prove their pre-formed conclusions.

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