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Vibe coding my way to a healthy family: Introducing Gamow Labs

ddmckinnon.com

21–30 of 138 posts

Re: Vibe coding my way to a healthy family: Introducing Gamow Labs

#21
That story is heart breaking. I really feel for you and your family. I quite literally cannot imagine having to make that decision regardless of how inevitable it was, and how much pain you felt.

No matter how short his life, or how much his suffering, Owen did get to experience being held by parents who loved him.

Re: Vibe coding my way to a healthy family: Introducing Gamow Labs

#22

Earlier quoted context omitted.

In what way?

lots of different ways, the loss of a child the potential loss of two children, the powerlessness and despair the parents would have been feeling... turning to AI which might have a positive outcome but many of us are not very trusting of the tool. Its a sad story. I wish them well, I hope this is one of those scenarios that AI works exactly as desired.

[dead]

Re: Vibe coding my way to a healthy family: Introducing Gamow Labs

#26

I’m skeptical that general purpose LLMs are a good fit for a very specialized medical analysis task. Something trained specifically for the task would be the path I’d explore.

> I’m skeptical that general purpose LLMs are a good fit for a very specialized medical analysis task

If they can save more lives without harming other lives I would gladly take it during the analysis. Even saving 1% more lives is an amazing achievement!

Re: Vibe coding my way to a healthy family: Introducing Gamow Labs

#28
Huh, this is fascinating. My wife and I did IVF with WGS in order to find a much less catastrophic shared genetic condition[0]. We have the FASTQs for my parents, and brother, and my wife and me, and our daughter (and our other embryos) and I've run it through the standard Opus[1] (since 4.5) and none have contradicted our genetic counselors or IVF doctors. This is an interesting, and devastating, condition far more severe than anything we risked. More power to the author for having coped in a productive way. I hope that more such science will lead to healthier babies, parents more comfortable with children since they know what they can avoid or mitigate, and happier families.

As an aside, I have not found SF to be anti-natal but that's because of the community we've formed. Of our friends in SF, almost all are trying for children or have them. Our shared Slack group is full of happy news. Inevitably, many of us must move elsewhere in order to allow them some freedom[2] and good education[3]. So there's a bit of a dead-sea effect, true, but even within that sea there are pockets of community one can find.

0: https://wiki.roshangeorge.dev/w/IVF but also see https://viz.roshangeorge.dev/roshan-genvue/ to see an old set of results and download my VCF here https://my.pgp-hms.org/profile/hu81A8CC and put it through a modern (but not too modern LLM) to get some fun results if you want a starter data set to peek through. Opus can get you far.

1: Fable as expected yields:

     Fable 5's safety measures flagged this message for cybersecurity or biology topics. They may flag safe, normal
    content as well. These measures let us bring you Mythos-level capability in other areas sooner, and we're working
    to refine them. Switched to Opus 4.8. Send feedback with /feedback or learn more
2: Within the last year 2 children have been killed in our neighbourhood by drivers, and parents in the US already compensate by cutting child freedom significantly

3: Since school system design is determined by both parents and non-parents, it is a vehicle of expression of non-education-related action by the latter, and in a city where they dominate the former, the effects are typical

Re: Vibe coding my way to a healthy family: Introducing Gamow Labs

#29

I’m skeptical that general purpose LLMs are a good fit for a very specialized medical analysis task. Something trained specifically for the task would be the path I’d explore.

I think author meant he vibe coded some deterministic system. Maybe comparing the whole genome to a healthy one, and pointing out all diffs?
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