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Study finds no evidence cannabis helps anxiety, depression, or PTSD

sciencedaily.com

21–30 of 244 posts

Re: Study finds no evidence cannabis helps anxiety, depression, or PTSD

#21

Isn't the lancet the same journal that has published the vax-autism and hydroxychloroquine studies?

The Lancet has been around for 200 years. It publishes weekly.

It's a highly regarded journal, but it doesn't mean 100% of the papers published are perfect.

If you're trying to dismiss a study because it was published in The Lancet then that's not a convincing line of reasoning to anyone who understands the scientific publishing landscape.

Re: Study finds no evidence cannabis helps anxiety, depression, or PTSD

#23

This is a hard topic to communicate in depression treatment. It's easy to mistake substances that temporarily boost your mood or calm your nerves for effective treatments for an underlying condition. There was a brief period of time before the opioid prescribing backlash when some fringe psychiatrists were proposing weaker opioids as adjunctive treatments for treatment resistant depression. It's hard to fathom now, b…

> but remember there was a period of time where many seemingly forgot about their addictive properties.

There was also quite alot of talk about how doctors, by being reticent to prescribe opioids, were inhumanely forcing patients to live in pain, and not being sufficiently deferential to patient autonomy. Moreover, the rhetoric was incorporated into discussions about racist disparities in treatment, given there was some evidence doctors were less likely to prescribe opioids to black patients, suggesting doctors were systematically being cruel. Naturally, the easiest way to dodge those accusations was to simply prescribe opioids as a matter of course. Even in the absence of Purdue Pharma pushing their claims about lack of significant addictive potential, there was already significant pressure to discount the risk of addiction.

Re: Study finds no evidence cannabis helps anxiety, depression, or PTSD

#24

The studies cited by this metastudy all suffer from the same issue: They aren't studying the cannabis plant at all and even if they are, it's not in the chemovars (chemical makeups) that real consumers are actually consuming - due to cannabis sourcing issues stemming from cannabis's continued illegality. For randomized controlled trials, even in "legal" states, university scientists can't just walk into a dispensary…

Using quantified isolates is the correct way to do a controlled study. Dosing is important. Claims that you need a special combination of exactly the right strains are just a way to move the goalposts forever. They could study 10 different strains in controlled trials and the same people would show up to dismiss this study because they weren't using some random strain that has some perfect combination of entourage ef…

I think that's a bit of a straw man.

You could study one combination that is broadly representative and is much much closer than the isolate.

Re: Study finds no evidence cannabis helps anxiety, depression, or PTSD

#25

This is a hard topic to communicate in depression treatment. It's easy to mistake substances that temporarily boost your mood or calm your nerves for effective treatments for an underlying condition. There was a brief period of time before the opioid prescribing backlash when some fringe psychiatrists were proposing weaker opioids as adjunctive treatments for treatment resistant depression. It's hard to fathom now, b…

This point of view makes no sense to me.

If you take it and you feel your anxiety is lessened, that's the greatest proof you can ask for. All the psychiatric studies are already based on self assessment.

Second, a lot of psychatric treatments are temporary, ending whenever the medication is stopped or wears off so I dont see how this would be any different

Re: Study finds no evidence cannabis helps anxiety, depression, or PTSD

#27

The studies cited by this metastudy all suffer from the same issue: They aren't studying the cannabis plant at all and even if they are, it's not in the chemovars (chemical makeups) that real consumers are actually consuming - due to cannabis sourcing issues stemming from cannabis's continued illegality. For randomized controlled trials, even in "legal" states, university scientists can't just walk into a dispensary…

Using quantified isolates is the correct way to do a controlled study. Dosing is important. Claims that you need a special combination of exactly the right strains are just a way to move the goalposts forever. They could study 10 different strains in controlled trials and the same people would show up to dismiss this study because they weren't using some random strain that has some perfect combination of entourage ef…

Way to completely misunderstand and try in an underhanded way to the dismiss entourage effect.

It’s not smoking 10 strains in a row it’s the fact that you need CBD THC and all the terpenes to get the effects. So the current growing trend of just getting the THC number higher tends to result in plants that don’t actually give people the full spectrum of effects, beneficial or not.

So the correct way to do this would be a full spectrum isolate, which again you coincidently forgot to mention I’m sure.

Re: Study finds no evidence cannabis helps anxiety, depression, or PTSD

#30
Matthew Hill offers a great interview on Andrew Huberman's podcast - https://open.spotify.com/episode/26PR93gyNcs8YPlQ9dypW3?si=V...

As someone who's used cannabis regularly for over a decade, I tried to start to explain in this body my experience but every sentence written ends with me deciding, "that's too circumstantial to my lifestyle-physiology to include."

I think at the end of the day, empirical research's purpose is to get us closer to being able to just make our own decisions surrounding mind-altering drugs. Beyond that, cannabis affects a great deal of systems in our body concurrent to the rest of our environment's effects. Use your autonomy to determine if it's a positive or a negative for you. Don't drive fucked up, please.

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