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Continuous glucose monitors reveal variable glucose responses to the same meals

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Re: Continuous glucose monitors reveal variable glucose responses to the same meals

#21

Post by jzacharia »

ddorian43 wrote: post #14
stranded22 wrote: post #6

Yep. My wife is T1D and this is infuriating for her. She’ll think that she’s cracked it, and then the next day, with the same meal at the same time, her sugar levels go high. Her words: there is nothing else where you have studied for over 30 years and STILL feel like you know nothing. It is incredibly demoralising for her sometimes - especially when she’s suffering also from a high/low sugar level. I have the upmost…

How about just not eat carbs at all and have more consistent & lower blood sugar? (this was an interesting case https://www.youtube.com/watch?v=CG8UU7P8FBU ) I do keto diet long term but for other reasons, often the epilepsy version where it's more strict and higher fat.

Keto works well, but I'm concerned about the extreme fat intake. I did manage to lower my A1C from 9s to mid 5s using Keto as a T1D, but eventually settled into a high protein, moderate fat, low-ish carb diet and that has worked pretty well without being hyper-restrictive. Heavily inspired by the late Dr. Richard K. Bernstein.

Re: Continuous glucose monitors reveal variable glucose responses to the same meals

#22

Post by crazygringo »

mjburgess wrote: post #11
csours wrote: post #8

Some assumptions are so obvious no one bothers to state them, or even remember them. Assumption: Medical professionals are trained to use Evidence Based Medicine (EBM). One might assume that EBM means something specific, and I'm sure it does, but that specific thing is different for different people. One thing that EBM sometimes means is: common sense is no substitute for evidence. There are uncountable times that co…

A counter-point, in a certain sense: when the conclusions of scientific papers (in these softer science fields), contradict common sense, they tend to be unreproducible; the ones which don't, are. The problem with studying humans is, roughly, the central limit theorem doesnt work: properties of biological and social systems do not have well-behaved statistics. So all this t-test pseudoscience can be a great misdirect…

> when the conclusions of scientific papers (in these softer science fields), contradict common sense, they tend to be unreproducible; the ones which don't, are.

Citation needed?

I don't know what would lead to that conclusion. And it would seem to run counter to the entire history of the field of psychology, for example.

Re: Continuous glucose monitors reveal variable glucose responses to the same meals

#23

Post by jzacharia »

msarrel wrote: post #2

Fascinating. I've always felt that this was true with my own body, yet every medical professional I've spoken to said that I was wrong.

Hate to sound like "that guy" but a majority of medical professionals are running their practice on outdated data or false studies funded by pharma.

Re: Continuous glucose monitors reveal variable glucose responses to the same meals

#24

Post by perrygeo »

taeric wrote: post #5

Odd, I would have expected this to be somewhat the case? Specifically, I would expect your activity leading into the meals, along with your expectations of what you will be doing after, would have some impact? Probably more impact from how hungry you were going into a meal. If you were already sated, for example, I'd expect your body to largely try and push the meal through as fast as it can. Neat to see what other p…

I'm very sensitive to sugar and starch when "at rest". If I wake up first thing in the morning and drink an orange juice or have a bowl of white rice before bed, my blood sugar and mood are out of control. But the same foods mid-day before/after/during intense mental or physical work are very well tolerated if not beneficial. So my priors agree with yours, timing and context absolutely matters.

Re: Continuous glucose monitors reveal variable glucose responses to the same meals

#25

Post by je42 »

stranded22 wrote: post #6

Yep. My wife is T1D and this is infuriating for her. She’ll think that she’s cracked it, and then the next day, with the same meal at the same time, her sugar levels go high. Her words: there is nothing else where you have studied for over 30 years and STILL feel like you know nothing. It is incredibly demoralising for her sometimes - especially when she’s suffering also from a high/low sugar level. I have the upmost…

More data can help inform semi closed loop systems to deal with this variability.

For example, AAPS has since version 3.2 dynamic IFS. ( https://androidaps.readthedocs.io/en/latest/DailyLifeWithAap... )

For me this works quite well

Re: Continuous glucose monitors reveal variable glucose responses to the same meals

#26

Post by ddorian43 »

jzacharia wrote: post #21
ddorian43 wrote: post #14

Earlier quoted context omitted.

How about just not eat carbs at all and have more consistent & lower blood sugar? (this was an interesting case https://www.youtube.com/watch?v=CG8UU7P8FBU ) I do keto diet long term but for other reasons, often the epilepsy version where it's more strict and higher fat.

Keto works well, but I'm concerned about the extreme fat intake. I did manage to lower my A1C from 9s to mid 5s using Keto as a T1D, but eventually settled into a high protein, moderate fat, low-ish carb diet and that has worked pretty well without being hyper-restrictive. Heavily inspired by the late Dr. Richard K. Bernstein.

I target for high ketones (1.5+) & low glucose 4-5mmol (blood test 1 hour after wake up) and higher protein interferes with both of them.

Re: Continuous glucose monitors reveal variable glucose responses to the same meals

#27

Post by siliconc0w »

Is this already pretty expected? We already knew that glucose response was highly dependent on time of day, pre or post meal movement, and whether the meal is moderated by other components like fats that can slow down the immediate impact.

Re: Continuous glucose monitors reveal variable glucose responses to the same meals

#28

Post by bilsbie »

blindriver wrote: post #19

I've been diagnosed with Type 2 diabetes and wear a CGM. I find that my blood glucose spikes much later than what is suggested. For example, I might eat a meal and my blood glucose doesn't spike until after 2 hours. When it spikes, I see the body react with insulin and it drives my blood sugar levels down, so I'm not sure if I actually do have T2D or if this is just how my body works. Another thing I've noticed is th…

Interesting. What’s your a1c level ?

I think you could have a point at around 100-105 baseline but 120 seems too high.

Re: Continuous glucose monitors reveal variable glucose responses to the same meals

#29

Post by layer8 »

taeric wrote: post #5

Odd, I would have expected this to be somewhat the case? Specifically, I would expect your activity leading into the meals, along with your expectations of what you will be doing after, would have some impact? Probably more impact from how hungry you were going into a meal. If you were already sated, for example, I'd expect your body to largely try and push the meal through as fast as it can. Neat to see what other p…

The study used 7-day rotating meals, so one would expect some consistency on average in a weekly rhythm, but it also only covered 14 days, so only two data points per meal and participant, if I read this correctly. In that case, I’m not surprised either that there is a lot of variation, also considering that this is a new meal regimen for the participants.

Re: Continuous glucose monitors reveal variable glucose responses to the same meals

#30

Post by blindriver »

bilsbie wrote: post #28
blindriver wrote: post #19

I've been diagnosed with Type 2 diabetes and wear a CGM. I find that my blood glucose spikes much later than what is suggested. For example, I might eat a meal and my blood glucose doesn't spike until after 2 hours. When it spikes, I see the body react with insulin and it drives my blood sugar levels down, so I'm not sure if I actually do have T2D or if this is just how my body works. Another thing I've noticed is th…

Interesting. What’s your a1c level ? I think you could have a point at around 100-105 baseline but 120 seems too high.

It's high, like 6.7-6.9. It doesn't make sense to me because that would suggest average blood glucose of over 150, but it's objectively around 120.
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