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Twice-Yearly HIV Shot Shows 100% Effectiveness in Women

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Re: Twice-Yearly HIV Shot Shows 100% Effectiveness in Women

#24

This is incredibly exciting! The main method available for PrEP, in the United States, at least, is a daily pill. I think (I don't know) there is a monthly shot, too. Daily pills take a lot of time investment; monthly shots are better; but once every 6 months is awesome! Especially in circumstances where it might be difficult to guarantee a daily pill or even a monthly shot.

> Daily pills take a lot of time investment; monthly shots are better That is a matter of opinion. How much time do you think it takes to swallow a pill?

I know from experience that I'm not able to take a vitamin D pill every day in the winter months to combat winter depression. It's actually kinda difficult to build habits like that, and I'd have to remember to bring it with me wherever I may go and stay for a couple of days.

Re: Twice-Yearly HIV Shot Shows 100% Effectiveness in Women

#25
post #20

This is incredibly exciting! The main method available for PrEP, in the United States, at least, is a daily pill. I think (I don't know) there is a monthly shot, too. Daily pills take a lot of time investment; monthly shots are better; but once every 6 months is awesome! Especially in circumstances where it might be difficult to guarantee a daily pill or even a monthly shot.

[flagged]

From USAID:

> When used correctly and consistently, male condoms are estimated to be 90 percent effective in reducing HIV transmission.

They work to a degree, but they're not perfect

Re: Twice-Yearly HIV Shot Shows 100% Effectiveness in Women

#26
post #24

Earlier quoted context omitted.

> Daily pills take a lot of time investment; monthly shots are better That is a matter of opinion. How much time do you think it takes to swallow a pill?

I know from experience that I'm not able to take a vitamin D pill every day in the winter months to combat winter depression. It's actually kinda difficult to build habits like that, and I'd have to remember to bring it with me wherever I may go and stay for a couple of days.

Interesting. Such variance in humans.

I find such things inordinately simple. I wake, stretch, urinate, go take my vitamins and drink two glasses of water. A third follows me to my current home office, where I process emails, alerts, whatever may be.

I find the best time to triage overnight emails is when I'm not quite awake yet to realise I'm doing it. Less pain that way.

The key is it being part of a routine, and the easiest is a part of the wake routine. At least for me. Which is why I find human variance interesting.

Meanwhile scheduling something 6+ months out (a doctor's appointment, or maybe at a pharmacy) for a shot is quite difficult to keep on time. I have to schedule, I have to keep free, I have to keep it in my mental space (calendars on phones help, but still...).

I literally don't know what part of the planet I will be on in a week. How on Earth could I know where to schedule such a thing, months or even weeks in advance?

Yet I bet for the parent poster, scheduling things like this is a breeze. Wild. Totally incomprehensible for me, as maybe it being easy for me to daily schedule is for them?

Re: Twice-Yearly HIV Shot Shows 100% Effectiveness in Women

#27
post #13
post #3

> and results published Wednesday show it worked nearly as well in men. So not as well? Is there a biological reason for this? Also, is it typical to do such studies on single genders rather than on a mix of humans?

HIV has heavily…gendered outcomes. Others have mentioned infection rates, there’s also sheer exposure rates to consider. https://www.cdc.gov/hiv-data/nhss/estimated-hiv-incidence-an...

This varies between countries. In South Africa, the country with the largest HIV positive population, women have double the HIV incidence of men. https://sph.brown.edu/news/2024-11-07/south-africa-hiv-obste...

Re: Twice-Yearly HIV Shot Shows 100% Effectiveness in Women

#28
post #20

This is incredibly exciting! The main method available for PrEP, in the United States, at least, is a daily pill. I think (I don't know) there is a monthly shot, too. Daily pills take a lot of time investment; monthly shots are better; but once every 6 months is awesome! Especially in circumstances where it might be difficult to guarantee a daily pill or even a monthly shot.

[flagged]

In some parts of the world, rape victims are a frequent recipient of HIV. I imagine their assailants don't feel obligated to wear a condom.

Please recall the regions of the world where these shots are going to be the least expensive, etc, per the article.

Re: Twice-Yearly HIV Shot Shows 100% Effectiveness in Women

#29
post #20

Earlier quoted context omitted.

[flagged]

In some parts of the world, rape victims are a frequent recipient of HIV. I imagine their assailants don't feel obligated to wear a condom. Please recall the regions of the world where these shots are going to be the least expensive, etc, per the article.

I think this is a great initiative for poor areas of the world like sub-Saharan Africa.

In the first world there are other options available.

Re: Twice-Yearly HIV Shot Shows 100% Effectiveness in Women

#30
post #21

Great news that it's so effective in women. Less great news is that availability to people who could use it the most is based on the whims of the drug maker.

At least for now, PrEP is available on most/all drug plans for free or very, very cheap, in the United States https://www.goodrx.com/truvada. No idea what happens when the ACA is further harmed.

And per the article,

> Drugmaker Gilead said it will allow cheap, generic versions to be sold in 120 poor countries with high HIV rates — mostly in Africa, Southeast Asia and the Caribbean.

So, the places that need it most will be able to get it for cheap. This is about as positive of a result as can be with how the modern world is currently laid out.

The people that need it the most in the countries that need it the most will likely be able to get it.

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