These aircraft were built with human limitations in mind, take away the human dependency and you can engineer aircraft capable of much higher Gs for longer.
I often wonder if drones even need to look like they do or if there is a more efficient design that we don't use simply because "things that fly look like this" where "this" includes a place for a cockpit.
The basic design of wings sticking out from a pointy cylinder isn't going to change, because of aerodynamics.
But in the case of the Predator drone, for example, it didn't reduce the volume of the "cockpit" -- it expanded it into a big bulge to fit the satellite antenna and all of the sensors.