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Ozempic will disrupt big tobacco, candy companies, and alcohol brands

curingaddiction.substack.com

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Re: Ozempic will disrupt big tobacco, candy companies, and alcohol brands

#21

Post by nvahalik »

someplaceguy wrote: post #16
akgoel wrote: post #7

Earlier quoted context omitted.

When I was on Ozempic, I just didn't want the milkshake. It rewires all reward centers.

May I ask about your experience since leaving Ozempic compared to before you started taking it? I'm not considering taking Ozempic nor am I aware of anyone who has, so I'm curious.

I haven't taken it, but my wife has and since she's been off, while she is eating more, it mainly appears to be maintenance as she's not really losing nor gaining weight anymore. Food just doesn't seem to be as big of a deal. We can enjoy a nice steak going out it's not as much as a draw.

Re: Ozempic will disrupt big tobacco, candy companies, and alcohol brands

#22

Post by scarmig »

Xenoamorphous wrote: post #9

I'm not very familiar with the approval process for new drugs, but as far as I know it involves some initial step where the safety is assessed, and then the effectiveness. But I don't think either of those are actually long term processes (like, longer than 5 years). So it scares me a bit when something like Ozepmic pops up and tons of people jump on it, without knowing the long term effects that might appear. I read…

There's always tradeoffs. Ozempic probably has some long term side effects, but are they worse than obesity? Probably not. (And an intervention based on ozempic is far more likely to cause lasting change than one based on a prescribed behavioral program.)

Re: Ozempic will disrupt big tobacco, candy companies, and alcohol brands

#23

Post by whatthesmack »

Xenoamorphous wrote: post #9

I'm not very familiar with the approval process for new drugs, but as far as I know it involves some initial step where the safety is assessed, and then the effectiveness. But I don't think either of those are actually long term processes (like, longer than 5 years). So it scares me a bit when something like Ozepmic pops up and tons of people jump on it, without knowing the long term effects that might appear. I read…

GLP-1 agonists have been around for a while. They're just gaining popularity lately, it seems. The first one was approved in the US in 2005 (exenatide).

Re: Ozempic will disrupt big tobacco, candy companies, and alcohol brands

#24

Post by slfnflctd »

If these drugs turn out to be significantly more effective for a wide range of addictions than past approaches, that would indeed be a major societal shift.

I wouldn't try any of them right now, but if my insurance covered one for treating alcoholism at some point I'd give it a shot. If it actually worked it would likely significantly improve not only my life experience, but also my productivity and thereby the lives of others I have an impact on. It's a nice thought.

Re: Ozempic will disrupt big tobacco, candy companies, and alcohol brands

#25

Post by pain_perdu »

raziel2701 wrote: post #17

Ozempic costs $1000/month (in the US) but $5/month to manufacture [0]. I think if this drug and others are to have a significant anti-consumption effect on other companies it needs to be vastly more accessible, which first requires more accessible healthcare in the US, which is unlikely to happen. Also it's an injection, which raises the barrier. If drugs like these become orally administered and over-the-counter, th…

Rybelsus is an oral version of semaglutide which has good efficacy.

Re: Ozempic will disrupt big tobacco, candy companies, and alcohol brands

#26

Post by 01100011 »

raziel2701 wrote: post #17

Ozempic costs $1000/month (in the US) but $5/month to manufacture [0]. I think if this drug and others are to have a significant anti-consumption effect on other companies it needs to be vastly more accessible, which first requires more accessible healthcare in the US, which is unlikely to happen. Also it's an injection, which raises the barrier. If drugs like these become orally administered and over-the-counter, th…

Plenty of ongoing research into orally active analogs and cheaper variants. Give it a year or two.

Re: Ozempic will disrupt big tobacco, candy companies, and alcohol brands

#27

Post by hackerlight »

Xenoamorphous wrote: post #9

I'm not very familiar with the approval process for new drugs, but as far as I know it involves some initial step where the safety is assessed, and then the effectiveness. But I don't think either of those are actually long term processes (like, longer than 5 years). So it scares me a bit when something like Ozepmic pops up and tons of people jump on it, without knowing the long term effects that might appear. I read…

The status quo (obesity) is extremely dangerous, so whatever potential danger you're thinking may exist would have to exceed that.

Re: Ozempic will disrupt big tobacco, candy companies, and alcohol brands

#28

Post by [deleted] »

Xenoamorphous wrote: post #9

I'm not very familiar with the approval process for new drugs, but as far as I know it involves some initial step where the safety is assessed, and then the effectiveness. But I don't think either of those are actually long term processes (like, longer than 5 years). So it scares me a bit when something like Ozepmic pops up and tons of people jump on it, without knowing the long term effects that might appear. I read…

[deleted]

Re: Ozempic will disrupt big tobacco, candy companies, and alcohol brands

#29

Post by [deleted] »

scarmig wrote: post #22
Xenoamorphous wrote: post #9

I'm not very familiar with the approval process for new drugs, but as far as I know it involves some initial step where the safety is assessed, and then the effectiveness. But I don't think either of those are actually long term processes (like, longer than 5 years). So it scares me a bit when something like Ozepmic pops up and tons of people jump on it, without knowing the long term effects that might appear. I read…

There's always tradeoffs. Ozempic probably has some long term side effects, but are they worse than obesity? Probably not. (And an intervention based on ozempic is far more likely to cause lasting change than one based on a prescribed behavioral program.)

[deleted]

Re: Ozempic will disrupt big tobacco, candy companies, and alcohol brands

#30

Post by jakub_g »

raziel2701 wrote: post #17

Ozempic costs $1000/month (in the US) but $5/month to manufacture [0]. I think if this drug and others are to have a significant anti-consumption effect on other companies it needs to be vastly more accessible, which first requires more accessible healthcare in the US, which is unlikely to happen. Also it's an injection, which raises the barrier. If drugs like these become orally administered and over-the-counter, th…

In worst case, Ozempic patents expire in 2031, which is not that far.
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