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Brain waves appear to wash out waste during sleep in mice

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Re: Brain waves appear to wash out waste during sleep in mice

#21

Post by ineedaj0b »

We need to figure out what activity or thought creates waves most similar to the cleaning function.

Maybe it’s dreaming? Dreaming by my experience is tedious and not restful… I have 4-6 dreams every night and never feel like I’m truly asleep.

Shouldn’t be hard to figure out with an EKG and a decent graph to see what your aiming for.

Re: Brain waves appear to wash out waste during sleep in mice

#26

Post by steve1977 »

lwansbrough wrote: post #17
pulse7 wrote: post #8

So garbage collection is not such a bad idea after all...

1/3 of compute time spent on garbage collection is pretty inefficient!

Maybe it's comforting to think that the time is not only spent with garbage collection. That's one part of sleep, but by far not the only one.

Re: Brain waves appear to wash out waste during sleep in mice

#27

Post by huppeldepup »

speedylight wrote: post #20
huppeldepup wrote: post #18

There is an mri greyscale clip that shows this process I saw a couple of years ago but could never find it back. It showed spinal fluid “washing” the brain. If anyone knows where I can find it, please link.

There’s this one I just found - [ https://player.vimeo.com/video/370150539?background=1](https...

That one is the default google answer, but not the one I saw. Mine had a spine attached and there was no highlighting, the fluid movements were distinguishable in the scans.

Thank you for trying.

Re: Brain waves appear to wash out waste during sleep in mice

#28

Post by VagabundoP »

achow wrote: post #3

More details at Washington Univ' site: https://medicine.wustl.edu/news/neurons-help-flush-waste-out... Could not find any free access to the paper, even though the Univ' says "This work was supported by the National Institutes of Health (NIH); the BJC Investigators Program at Washington University; and the Neuroscience Innovation Foundation." These kind of grant funded research should be accessible at the least from…

Checked and it was published through Nature:

Jiang-Xie, LF., Drieu, A., Bhasiin, K. et al. Neuronal dynamics direct cerebrospinal fluid perfusion and brain clearance. Nature 627, 157–164 (2024). https://doi.org/10.1038/s41586-024-07108-6

Every Uni should have access through your library system.

Re: Brain waves appear to wash out waste during sleep in mice

#29

Post by pjerem »

ineedaj0b wrote: post #21

We need to figure out what activity or thought creates waves most similar to the cleaning function. Maybe it’s dreaming? Dreaming by my experience is tedious and not restful… I have 4-6 dreams every night and never feel like I’m truly asleep. Shouldn’t be hard to figure out with an EKG and a decent graph to see what your aiming for.

It’s not dreaming that is tedious. My understanding is that the brain always dream but that you only remember your dreams if you wake up during them. So, remembering 4-6 dreams would mean that you wake up (probably unconsciously) multiple times per night. It’s probably what is tiring rather than the dream itself.

Disclaimer : I have no source and I may be wrong. It’s my understanding.

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