Live data from Hacker News

Confocal microscopy

en.wikipedia.org

21–22 of 22 posts

Re: Confocal microscopy

#21
post #9

Not sure why this article made it to front page, but fwiw, I used to work as a research engineer in a role where using a confocal microscope in clinical trial settings was a regular part of my job. AMA :D

Meta: I submitted it ~2 months ago because I ran into the topic for work reasons. I found the connection to Minsky reason enough since I didn't know that, and also the technology itself is of course very cool and probably not well known outside the relevant fields. The post did not get a lot of attention, but a couple of days ago I got what I think is my first offer to re-post from the admins, and since I still found…

> it seems people are more inclined to question submissions' topicality these days, which I find a bit stressful

I think it's OK when people question a topic and the answer expands their minds.

Re: Confocal microscopy

#22
post #14

I was offered a 3d laserscanning microscope that combines confocal microscopy with interferometry. Manufacturer claims resolution "up to 0,01nm", (10pm), not a typo. That is quite remarkable if true but I wonder what that even means...

My guess would be they're using green light, measuring phase with a 16-bit DAC, and implicitly fibbing about their signal-to-noise ratio. That's baked in to "up to".
Post reply on HN