21–22 of 22 posts
Earlier quoted context omitted.
No-one can read the future. But I'm sure you read in TFA about the kill switch
The best way to develop GMO technologies is to regulate it after it injures millions of people. And that regulation is... declaring anyone who questions the science a terrorist.
I doubt we'll get anywhere thrashing this out, but I'll concede that the apocalypse is undesirable
Really cool area for emerging biotech. Insulin production circuits like the ones described in this article have inspired (and frustrated) synthetic biologists for a long time. For anyone who approaches biotech with an engineering mindset, insulin makes for a very clean and well-posed problem. 1) Medical insulin is already produced by engineered microbes, and has been for 40 years. So we know microbes can do this safe…
True, but with the exception of type I diabetics (a relatively small proportion of all diabetics, about 3% of total), the goal is to avoid insulin treatment.
What you want to do is reverse insulin resistance, while restoring blood glucose control. Basically reverse metabolic syndrome. That's what the therapies like SGLT2 inhibitors, GLP1s, DPP-4 inhibitors, etc.
If a type II patient gets to the point of needing exogenous insulin, you've basically reached the end of the line.