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Researchers discover physical cause of long Covid tiredness

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Re: Researchers discover physical cause of long Covid tiredness

#21

Post by fsiefken »

xerox13ster wrote: post #8
kick_in_the_dor wrote: post #5

> we saw that the mitochondria of the muscle, also known as the energy factories of the cell *Ahem*, powerhouse of the cell Jokes aside, this is a terrifying stat: "Although the majority of people infected with the SARS-CoV-2 virus recover within weeks...around one in eight will get long-COVID. Symptoms in patients with long-COVID...include severe cognitive problems (brain fog), fatigue, exercise intolerance, autonom…

Even more terrifying considering we can be reinfected multiple times so we might be rolling those odds every time. E: changed "we are" to "we might be"

Yes, but isn't it more like if there is perhaps a factor X you don't belong to the 1/8 risk group that the chances that with subsequent infections you get long covid-19 is smaller (or near zero)? It's likely that this factor exists as lots of people got infected multiple times and not everybody has long covid-19. Is it a matter of rolling those odds every time for everyone or is that only for 1 in 8 people or would they get long covid-19 100% after each infection. Would mRNA vaccines adequately protect this group from long COVID-19?

Re: Researchers discover physical cause of long Covid tiredness

#22

Post by m3kw9 »

kick_in_the_dor wrote: post #5

> we saw that the mitochondria of the muscle, also known as the energy factories of the cell *Ahem*, powerhouse of the cell Jokes aside, this is a terrifying stat: "Although the majority of people infected with the SARS-CoV-2 virus recover within weeks...around one in eight will get long-COVID. Symptoms in patients with long-COVID...include severe cognitive problems (brain fog), fatigue, exercise intolerance, autonom…

What about a spectrum of long Covid? Maybe you can be fine but you are actually 80%, not enough to notice but enough to affect your full potential?

Re: Researchers discover physical cause of long Covid tiredness

#23

Post by johnchristopher »

frakt0x90 wrote: post #11
xerox13ster wrote: post #8

Earlier quoted context omitted.

Even more terrifying considering we can be reinfected multiple times so we might be rolling those odds every time. E: changed "we are" to "we might be"

It would be interesting to know if the odds decrease with reinfection. Are there any studies on that?

https://www.sciencealert.com/every-covid-infection-increases... (just saw this one today, links to studies in the article)

Re: Researchers discover physical cause of long Covid tiredness

#24

Post by babypuncher »

progrus wrote: post #17
OJFord wrote: post #15

Earlier quoted context omitted.

Not to mention the absurd arbitrariness of it if not even willing to propose a mechanism for it.

One mechanism is physiological stress when people believe they’ve been cursed: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1447278/

You keep bringing that up, but Long Covid is exceptionally well documented at this point. We can't pretend it's entirely in peoples heads like you seem to be doing.

Re: Researchers discover physical cause of long Covid tiredness

#25

Post by faitswulff »

blindriver wrote: post #18
kick_in_the_dor wrote: post #5

> we saw that the mitochondria of the muscle, also known as the energy factories of the cell *Ahem*, powerhouse of the cell Jokes aside, this is a terrifying stat: "Although the majority of people infected with the SARS-CoV-2 virus recover within weeks...around one in eight will get long-COVID. Symptoms in patients with long-COVID...include severe cognitive problems (brain fog), fatigue, exercise intolerance, autonom…

There is nothing to be “terrified” about. You are conflating different types of “long covid”. Some covid infections, just like the cold or the flu, cause symptoms longer than the 5-7 days, maybe for 2-3 weeks. That’s long covid. Also remember that long covid symptoms include symptoms like depression and it ends up not being very rigorously defined. Then there is the version that creates long term chronic fatigue symp…

> Some covid infections, just like the cold or the flu, cause symptoms longer than the 5-7 days

That's arguably also terrifying if even common viruses are known to cause long term conditions. Also consider the evidence pointing to a link between viral infection and dementia:

https://www.sciencealert.com/a-study-of-500000-medical-recor...

Re: Researchers discover physical cause of long Covid tiredness

#26

Post by spion »

fsiefken wrote: post #21
xerox13ster wrote: post #8

Earlier quoted context omitted.

Even more terrifying considering we can be reinfected multiple times so we might be rolling those odds every time. E: changed "we are" to "we might be"

Yes, but isn't it more like if there is perhaps a factor X you don't belong to the 1/8 risk group that the chances that with subsequent infections you get long covid-19 is smaller (or near zero)? It's likely that this factor exists as lots of people got infected multiple times and not everybody has long covid-19. Is it a matter of rolling those odds every time for everyone or is that only for 1 in 8 people or would t…

AFAIK, gene links have only been found for persistent cough and shortness of breath, but not other long covid symptoms.

Protection from vaccines has ranged (IIRC) from none to about 50% reduction in probability

Re: Researchers discover physical cause of long Covid tiredness

#27

Post by OJFord »

progrus wrote: post #17
OJFord wrote: post #15

Earlier quoted context omitted.

Not to mention the absurd arbitrariness of it if not even willing to propose a mechanism for it.

One mechanism is physiological stress when people believe they’ve been cursed: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1447278/

So that would affect people who are anti-vaccination (believe it's a curse) and got it anyway?

I think there's far more reports of the 'long covid' symptoms than there are people in that camp.

Re: Researchers discover physical cause of long Covid tiredness

#28

Post by alpaca128 »

progrus wrote: post #19

Am I supposed to believe that these physiological effects have nothing to do with fear of the virus? https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1447278/

If it's psychosomatic then why does it only happen with this specific virus and not, say, with chronic illnesses?

Re: Researchers discover physical cause of long Covid tiredness

#29

Post by mort96 »

blindriver wrote: post #18
kick_in_the_dor wrote: post #5

> we saw that the mitochondria of the muscle, also known as the energy factories of the cell *Ahem*, powerhouse of the cell Jokes aside, this is a terrifying stat: "Although the majority of people infected with the SARS-CoV-2 virus recover within weeks...around one in eight will get long-COVID. Symptoms in patients with long-COVID...include severe cognitive problems (brain fog), fatigue, exercise intolerance, autonom…

There is nothing to be “terrified” about. You are conflating different types of “long covid”. Some covid infections, just like the cold or the flu, cause symptoms longer than the 5-7 days, maybe for 2-3 weeks. That’s long covid. Also remember that long covid symptoms include symptoms like depression and it ends up not being very rigorously defined. Then there is the version that creates long term chronic fatigue symp…

You're right, and I wish we had terms to differentiate them. It's ridiculous that "chronic fatigue and brain fog for the rest of your life" and "flu-like symptoms for 3 weeks and then back to normal" are both discussed under the term "long covid".

Re: Researchers discover physical cause of long Covid tiredness

#30

Post by TylerE »

blindriver wrote: post #18
kick_in_the_dor wrote: post #5

> we saw that the mitochondria of the muscle, also known as the energy factories of the cell *Ahem*, powerhouse of the cell Jokes aside, this is a terrifying stat: "Although the majority of people infected with the SARS-CoV-2 virus recover within weeks...around one in eight will get long-COVID. Symptoms in patients with long-COVID...include severe cognitive problems (brain fog), fatigue, exercise intolerance, autonom…

There is nothing to be “terrified” about. You are conflating different types of “long covid”. Some covid infections, just like the cold or the flu, cause symptoms longer than the 5-7 days, maybe for 2-3 weeks. That’s long covid. Also remember that long covid symptoms include symptoms like depression and it ends up not being very rigorously defined. Then there is the version that creates long term chronic fatigue symp…

As someone without long COVID (or Covid ever). Your description of long COVID o only a little bit worse than a decent day for me. (Multiple chronic conditions, including multiple respitory). If I had chronic fatigue on top of what I already have, I’d be hardly capable of getting out of bed to go the bathroom. Working would be absolutely out of the question.
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