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RNA editing is common in behaviorally sophisticated coleoid cephalopods (2017)

pubmed.ncbi.nlm.nih.gov

21–30 of 31 posts

Re: RNA editing is common in behaviorally sophisticated coleoid cephalopods (2017)

#21
post #12

the beauty of having root access, as demonstrated by nature

This is purely speculation, but I wonder if this "root access" doesn't also come with downsides, e.g. more gene defects, which would help explain the short lifespan of most cephalopods.

* Deletes System32 *

* dies *

Re: RNA editing is common in behaviorally sophisticated coleoid cephalopods (2017)

#22
Here's a recent study employing modern imaging methods to observe and chart the activities in the brains of octopuses. It's quite surprising to find a high level of similarity with more advanced visual species.

Functional organization of visual responses in the octopus optic lobe https://www.sciencedirect.com/science/article/pii/S096098222...

Re: RNA editing is common in behaviorally sophisticated coleoid cephalopods (2017)

#23
post #7

They're cool but they're never taking over the planet. Suckers. On a more serious note, it's very interesting to see the different mechanisms that nature develops for adaptability. It seems like there's a trade off here between heredability and adaptability, with cephalopods favouring the second one. Meaning on a long scale their evolution might be slower but it allows them to overcome challenges on the short term mo…

> Suckers.

Yes, they have those.

Re: RNA editing is common in behaviorally sophisticated coleoid cephalopods (2017)

#24

> RNA editing, a post-transcriptional process, allows the diversification of proteomes beyond the genomic blueprint; however it is infrequently used among animals for this purpose. If I had written this and showed it to my PhD advisor, I would have gotten an earful about how "what do you mean by... be specific... what about...", etc. My PI was a nitpicker. Poor fools whose papers had to be edited by him... That said,…

I don't think that the essay refers to basic RNA splicing, but much more complex transcription templating.

If I remember correctly, cephalopods have an absolutely enormous amount of RNA editing going on, but it's so much so that their coding DNA is essentially fixed, because if any of it changes all the RNA editing falls over and they're non-viable.

Re: RNA editing is common in behaviorally sophisticated coleoid cephalopods (2017)

#25
post #12

the beauty of having root access, as demonstrated by nature

This is purely speculation, but I wonder if this "root access" doesn't also come with downsides, e.g. more gene defects, which would help explain the short lifespan of most cephalopods.

IIRC it greatly limits the long-term flexibility, because most DNA changes will either break RNA edition or cascade into undesirable post-edition features.

It's like taking a program at v0.1 and then developing the entire thing via binary patches, at one point you've got so much binary patching going on any edition and recompilation of the source makes them not work.

Re: RNA editing is common in behaviorally sophisticated coleoid cephalopods (2017)

#26
post #20

[flagged]

Maybe you can ask chatgpt if people want to read about someone else asking it questions or not.

Nobody cares what questions you typed into some llm front end. We can all do it to. If we wanted to we would. Instead we get no/low effort posts like yours.

Re: RNA editing is common in behaviorally sophisticated coleoid cephalopods (2017)

#27
post #7

They're cool but they're never taking over the planet. Suckers. On a more serious note, it's very interesting to see the different mechanisms that nature develops for adaptability. It seems like there's a trade off here between heredability and adaptability, with cephalopods favouring the second one. Meaning on a long scale their evolution might be slower but it allows them to overcome challenges on the short term mo…

On the one hand, we have digital watches.

On the other hand, we may be about to bring about our own extinction and I'm willing to bet squid will be around no matter how much surface warming and sea level rise there is.

Squid could well be the pinboard to our delicious ...

Re: RNA editing is common in behaviorally sophisticated coleoid cephalopods (2017)

#28
post #9

> RNA editing, a post-transcriptional process, allows the diversification of proteomes beyond the genomic blueprint; however it is infrequently used among animals for this purpose. If I had written this and showed it to my PhD advisor, I would have gotten an earful about how "what do you mean by... be specific... what about...", etc. My PI was a nitpicker. Poor fools whose papers had to be edited by him... That said,…

They split off so long ago that the most recent common ancestor of Cephalopods and mammals is a worm that lived ~500 million years ago: https://www.researchgate.net/figure/Phylogenetic-tree-depict... That gives plenty of time for some mechanism to evolve in one of the two branches and not in the other. RNA editing may not be rare in that part of the evolutionary tree but I do wonder if it was already present in that…

I love those evolutionary trees. I recently read “The Rise and Reign of Mammals” [1] and it’s so interesting to find out that all mammals, and therefore humans, evolved from what was mostly a glorified ground squirrel (my words, not his).

https://www.ucdavis.edu/curiosity/news/revealing-genome-comm...

[1] https://www.panmacmillan.com/authors/steve-brusatte/the-rise...

Re: RNA editing is common in behaviorally sophisticated coleoid cephalopods (2017)

#29
post #9

> RNA editing, a post-transcriptional process, allows the diversification of proteomes beyond the genomic blueprint; however it is infrequently used among animals for this purpose. If I had written this and showed it to my PhD advisor, I would have gotten an earful about how "what do you mean by... be specific... what about...", etc. My PI was a nitpicker. Poor fools whose papers had to be edited by him... That said,…

They split off so long ago that the most recent common ancestor of Cephalopods and mammals is a worm that lived ~500 million years ago: https://www.researchgate.net/figure/Phylogenetic-tree-depict... That gives plenty of time for some mechanism to evolve in one of the two branches and not in the other. RNA editing may not be rare in that part of the evolutionary tree but I do wonder if it was already present in that…

So long ago organs like eyes are an example of convergent evolution.

https://evolution-outreach.biomedcentral.com/articles/10.100...

Re: RNA editing is common in behaviorally sophisticated coleoid cephalopods (2017)

#30
post #29
post #9

Earlier quoted context omitted.

They split off so long ago that the most recent common ancestor of Cephalopods and mammals is a worm that lived ~500 million years ago: https://www.researchgate.net/figure/Phylogenetic-tree-depict... That gives plenty of time for some mechanism to evolve in one of the two branches and not in the other. RNA editing may not be rare in that part of the evolutionary tree but I do wonder if it was already present in that…

So long ago organs like eyes are an example of convergent evolution. https://evolution-outreach.biomedcentral.com/articles/10.100...

Fascinating, thank you for posting that. It ate up my whole day but it was well worth it.
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