We've gone away from system design interview questions on my team. We ask people to diagram something technical they understand well and the team digs in and asks questions to understand depth and breadth of the candidates understanding. For us it works much better. It's a chance to see how well candidates do in following instructions. It gives you a chance to explore depth and breadth of their knowledge on something…
Feels like an Architect interview more than a Senior interview though
Seniors should be able to build large, interconnected systems. IMO that's a basic skillset required to reach that level, and part of why I roll my eyes when I see people with 5, 4, 3 years of experience claiming to be seniors.