Personally I hope this works. I've always liked the name Karen. It would be great to see it get rehabilitated. I'm not a Karen, I don't know any Karens, but I can imagine that this must really suck for them. I knew an Osama at university in 2003. Poor guy had to change his name. Another nice name ruined.
I wonder why certain names acquire the infamy of their worst namesakes (e.g. Adolf) and not others (e.g. Vladimir, Joseph)