Yes, and on top of that I use a vertical left-handed mouse. I am right handed but my dad made me switch to driving a mouse with the left hand some 25 years ago. I am forever thankful to him for that :) First, you'll be faster because you can use keyboard with the right hand and drive a mouse with the left. Second, load on your right hand is automatically lower. And third, just use vertical mouse for a much more comfo…
Interesting that you like a 'special' (ie., not vanilla symmetric cheap'n'cheerful thing) mouse. I have not yet figured out (after [mumble] years) whether I want a keyboard/mouse setup that fits like a custom glove (the perfect mouse, the perfect keyboard with the perfect layout (colemak or some such), foot pedals for the shift keys, etc (haven't tried that, yet)) or a setup that I can make work for me at any kiosk... or some middle position between those two. Currently I'm at "make it work".