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Isomorphic Labs: Reimagining drug discovery with an AI-first approach

isomorphiclabs.com

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Re: Isomorphic Labs: Reimagining drug discovery with an AI-first approach

#21

Post by esyir »

isomorphic wrote: post #10

> [...] there may be a common underlying structure between biology and information science - an isomorphic mapping between the two - hence the name of the company. Biology is likely far too complex and messy to ever be encapsulated as a simple set of neat mathematical equations. ...uses a neatly-defined mathematical term to name the company, then rejects the idea of neat mathematics in practice.

Funnily enough, once of my mathematically inclined friends has had this exact issue with biological problems. Every time he tried breaking it down into a neat solution, the response from the bio side would inevitably start with "but" or "however".

Re: Isomorphic Labs: Reimagining drug discovery with an AI-first approach

#23

Post by pizza »

isomorphic wrote: post #10

> [...] there may be a common underlying structure between biology and information science - an isomorphic mapping between the two - hence the name of the company. Biology is likely far too complex and messy to ever be encapsulated as a simple set of neat mathematical equations. ...uses a neatly-defined mathematical term to name the company, then rejects the idea of neat mathematics in practice.

What Is Life? [0]

[0] https://en.wikipedia.org/wiki/What_Is_Life%3F

Re: Isomorphic Labs: Reimagining drug discovery with an AI-first approach

#24

Post by zippy5 »

rsfern wrote: post #18
zippy5 wrote: post #16

Earlier quoted context omitted.

I think it could be Nobel Prize worthy. Protein’s structure often determines its effect as a catalyst. So to map the DNA to the 2nd order outcomes seems like it could be the missing ingredient to controlling the properties of cells. Personally I’m hoping that someone smarter than me figures out how to displace existing catalysts like platinum and palladium. Seems like it could be a pretty penny and some positive envi…

Pt and Pd are pretty different from proteins in terms of the reactions they’re used to catalyze, but check out https://opencatalystproject.org/

This is wonderful. I’m going to see if there is anything I can build for this.

Re: Isomorphic Labs: Reimagining drug discovery with an AI-first approach

#25

Post by elcritch »

ampdepolymerase wrote: post #19
zippy5 wrote: post #16

Earlier quoted context omitted.

I think it could be Nobel Prize worthy. Protein’s structure often determines its effect as a catalyst. So to map the DNA to the 2nd order outcomes seems like it could be the missing ingredient to controlling the properties of cells. Personally I’m hoping that someone smarter than me figures out how to displace existing catalysts like platinum and palladium. Seems like it could be a pretty penny and some positive envi…

Protein catalysts almost always contain an inorganic atom. We will be able to make more efficient catalysts with better understanding of protein structure but the need for metals won't necessarily go away.

The protein catalysts can utilize more common metal ions instead of the rarer metals. Placing an iron atom in the right protein structure will affect the reaction probabilities.

Re: Isomorphic Labs: Reimagining drug discovery with an AI-first approach

#26

Post by rajnathani »

reidjs wrote: post #14
isomorphic wrote: post #10

> [...] there may be a common underlying structure between biology and information science - an isomorphic mapping between the two - hence the name of the company. Biology is likely far too complex and messy to ever be encapsulated as a simple set of neat mathematical equations. ...uses a neatly-defined mathematical term to name the company, then rejects the idea of neat mathematics in practice.

Do you disagree with that? I think the point they’re making is perfectly reasonable

See the poster's username, he/she is being a little too pedantic here :)
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