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RNA breakthrough creates crops that can grow 50 percent more potatoes, rice

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Re: RNA breakthrough creates crops that can grow 50 percent more potatoes, rice

#21
While I see people worry about the nutrient content in the resulting food, I wonder more about the nutrient content of the soil after a few years of such products. While we fertilize the soil, the mention of "longer and deeper roots" means that such plants will take out more from the ground, making ground less usable for future farming. Basically, as others have said, there is an evolutionary reason plants do not naturally grow this big (they'd kill themselves off in a few generations).

Sure, rotation of cultures is already common in farming, but this implies we'd move further away from organic farming rather than closer to it with the need to re-fertilize the soil to an even bigger extent (and deeper).

Or, it would make us move to other currently unexploited land, thus worsening the global situation we are in.

Basically, there is a potential in this, but I was never under the impression that any part of human population is starving because of us being unable to produce enough food (rather, it's waste and inequality, to name the likely top two).

Re: RNA breakthrough creates crops that can grow 50 percent more potatoes, rice

#22
post #7
post #2

How dangerous is this? Could we end up creating something indestructible like Japanese Knot weed except worse?

I predict that mRNA is going to be an obnoxious fad, where every marketer on the planet tries to leverage the concept/acronym/terminology into their product packaging (regardless of whether it's a medicine, a car part, a floor polish, ...) -- like how Blockchain became such a darling for several years.

I wouldn’t put Blockchain in the past tense here. Having recently conducted a job search in IT, the number of jobs, companies, and startups that are either completely focused on, or at least discussing blockchain is staggering. It’s in the same boat with IoT. With some job descriptions you get both! I can’t roll my eyes hard enough.

Re: RNA breakthrough creates crops that can grow 50 percent more potatoes, rice

#23
post #8

Earlier quoted context omitted.

It's probably about the same, it seems like the change is producing larger more robust plants which yield more. It doesn't seem like that should either the size of the rice grain itself or the nutrient content.

I don't think that's a safe assumption at all. In fact unless it's somehow increasing the rate of nutrient intake, doesn't that all but guarantee the nutrients are being used to make the base plant larger rather than going into the rice?

The abstract mentions how it leads to longer roots ("produced longer root systems"), which is probably the explanation for all the properties (it can extract water from deeper soil, and it can extract more nutrients from the soil).

My concern is how many generations of crops can one have in such a field before it needs artificial replenishing in the ways we do not do today (see my longer comment elsewhere on the thread :)).

Re: RNA breakthrough creates crops that can grow 50 percent more potatoes, rice

#24
post #6

How about nutrient content by mass, or some such measure? I skimmed the article, maybe I missed it. Aside: How easy is it to break into computational biology as a, say, practitioner of computational mechanics?

There’s a ton of bio specific domain knowledge you’d need to pick up. I haven’t met too many self taught comp bio people I’d imagine it’s the same as the number of self taught computational mechanics people.

From my limited experience (this could def not generalize) the two fields are very different in industry. Comp mech tends to be very design or analysis oriented and hence project management heavy. Generally you already have a product and are trying to refine it in some way. There’s also usually commercially available tools to do advanced FEA. For the most part people aren’t writing their own programs anymore.

Whereas comp bio tends to be more like data science applied to bio so it’s more of a software offshoot where projects feel more like full product development cycles where in some cases people produce software along with a final product. So you also need great coding skills.

Finally most comp bio people have phds. I don’t know if it’s a requirement for a job but that’s what I have seen. This may be a barrier.

To jump straight in could be very hard. Tho there may be other paths for example bioinformatics to learn domain and software then jump into comp bio once you have a base.

There’s also the going back to school option to pick up domain knowledge + credential but I’m generally against it just because of opportunity cost.

Anyway take all this with a grain of salt cause my experience/ what I’ve seen may be way off.

Finally def check out some free comp bio classes. I think Stanford and Berkeley have freely available online materials.

Re: RNA breakthrough creates crops that can grow 50 percent more potatoes, rice

#25
Original paper linked here (behind paywall) [0]. The researchers introduced the human FTO gene into plants to increase crop yields.

Would this be cannibalism?

You could use RNA demethylases from other organisms for sure, but it's a really interesting and weird concept, whether people would consider eating a plant expressing human proteins to be taboo.

[0] https://www.nature.com/articles/s41587-021-00982-9

Re: RNA breakthrough creates crops that can grow 50 percent more potatoes, rice

#26
post #21

While I see people worry about the nutrient content in the resulting food, I wonder more about the nutrient content of the soil after a few years of such products. While we fertilize the soil, the mention of "longer and deeper roots" means that such plants will take out more from the ground, making ground less usable for future farming. Basically, as others have said, there is an evolutionary reason plants do not nat…

>Basically, as others have said, there is an evolutionary reason plants do not naturally grow this big (they'd kill themselves off in a few generations).

The undomesticated cultivars which evolved over time evolved to work in their niche. Potatoes largely come from the Andes in Peru/Chile, where the soil is thin, rocky and the terrain is very mountainous.

So potatoes evolved to develop in poor quality mountainous soil.

What we do as humans in domesticating these cultivars is important because we grow potatoes in very different situations, and we develop new potato cultivar that are adapted to our new environments.

So you see, it's not "an evolutionary reason plants don't grow big", it's "they evolved to fill a niche". When we change the niche, we change the pressures on them, and we create an opportunity for us to adapt the new plant even better.

I don't think there is as much worry about fertilizer as you think. When growing crops we are long past the time when you rely on natural fertilizer. Nearly every atom in those plants that isn't Carbon was added to the soil explicitly to grow that plant. So, to grow bigger potato, you will need more fertilizer.

With regards to climate, being able to grow more rice per acre is valuable because climate change will destroy breadbasket regions and likely reduce total land available to agriculture. Thus maintaining total output levels against decreasing land total will be important.

Re: RNA breakthrough creates crops that can grow 50 percent more potatoes, rice

#27
post #21

While I see people worry about the nutrient content in the resulting food, I wonder more about the nutrient content of the soil after a few years of such products. While we fertilize the soil, the mention of "longer and deeper roots" means that such plants will take out more from the ground, making ground less usable for future farming. Basically, as others have said, there is an evolutionary reason plants do not nat…

> Basically, as others have said, there is an evolutionary reason plants do not naturally grow this big (they'd kill themselves off in a few generations).

I don't know that this is solid reasoning. Certainly there is some limit eventually imposed by soil nutrient content but there could also be other reasons plants don't grow large fruit. A big one being that plants which grow their fruit to spread seeds reach efficiency when there is enough fruit to attract a spreading organism and no more.

In fact, basically all the plants we consume were already unusually large even before the green revolution. Humans had selected or hybridized the popular cultivars to an extreme already.

Again, I'm not saying it's impossible that this size of plant crosses some threshold for the soil, it's just not safe to assume it does either.

Re: RNA breakthrough creates crops that can grow 50 percent more potatoes, rice

#28
Perhaps there's a net good application to this, more yield so a plant can produce more, feed more hungry people, survive storage and shipping -- but I see 4lbs packs of Driscoll strawberries at my store, year round. The fruits are gigantic, way bigger than what a strawberry should be, firm, uniformly red, and absolutely tasteless. Same with tomatoes, bananas, potatoes, anything you could buy at a typical grocery store. Especially tomatoes, you can taste what an astounding difference between a commercially produced tomato (even with monikers like vine-ripened, kumato, heirloom, etc.) and an ugly homegrown one. I don't want this future, but my want is at odds with that of the producers: what's wrong with fresh tomatoes and basil year round? and that of the poor: what's wrong with affordable berries, asparagus, good-tasting not-mealy apples?

I remember when honeycrisps first came on the market, they were smaller, now they are gigantic, I don't know if they taste more diluted. I also remember green plumcots, they used to be smaller, more tart and sweet. Now they are huge!

Re: RNA breakthrough creates crops that can grow 50 percent more potatoes, rice

#29

Original paper linked here (behind paywall) [0]. The researchers introduced the human FTO gene into plants to increase crop yields. Would this be cannibalism? You could use RNA demethylases from other organisms for sure, but it's a really interesting and weird concept, whether people would consider eating a plant expressing human proteins to be taboo. [0] https://www.nature.com/articles/s41587-021-00982-9

They probably used the human version for laziness, because it is probably available on the shelf. If it causes too many problems for the PR department, they can switch to the chimpanzee version, or the mice version. They are very similar (or identical?).

Re: RNA breakthrough creates crops that can grow 50 percent more potatoes, rice

#30

Original paper linked here (behind paywall) [0]. The researchers introduced the human FTO gene into plants to increase crop yields. Would this be cannibalism? You could use RNA demethylases from other organisms for sure, but it's a really interesting and weird concept, whether people would consider eating a plant expressing human proteins to be taboo. [0] https://www.nature.com/articles/s41587-021-00982-9

And of you would consider it taboo, would you still if the same generic sequence were found in another species?
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