Hacker News Board Hacker News, browsed like a classic message board
Live data from Hacker News

Inflammation, but Not Telomere Length, Predicts Ageing at Extreme Old Age

pubmed.ncbi.nlm.nih.gov

Post reply on HN
Print view View original

21–30 of 157 posts

Re: Inflammation, but Not Telomere Length, Predicts Ageing at Extreme Old Age

#21

Post by [deleted] »

atat7024 wrote: post #16
legerdemain wrote: post #7

Earlier quoted context omitted.

Inflammation is a basic life process, not a reaction to the food you eat. Inflammation plays an active part in wound-healing. Teething in infants has an inflammatory component. Systemic inflammation is ubiquitous during and following parturition in mammals. There is inflammation everywhere, it's as generic a word as "oxidation" and "metabolism."

Every time you eat, the body enters a state of heightened inflammation. This is well documented. Please don't spread disinformation.

[deleted]

Re: Inflammation, but Not Telomere Length, Predicts Ageing at Extreme Old Age

#22

Post by agumonkey »

TimSchumann wrote: post #3

Anecdote, but this may explain why I feel so much healthier when I'm fasting regularly. Turns out, if you stop putting everything but water/salt in your body, there's not much left that causes inflammation.

I cut antidepressant but I know how brain chemistry feels now. While I was doing the "one meal a day thing", whenever I felt hunger, a few minutes after my brain felt a bit like when I used pills. It's a very shallow anecdata but I can't help but to think about importance of the gut-brain axis.

Re: Inflammation, but Not Telomere Length, Predicts Ageing at Extreme Old Age

#24

Post by voxl »

atat7024 wrote: post #16
legerdemain wrote: post #7

Earlier quoted context omitted.

Inflammation is a basic life process, not a reaction to the food you eat. Inflammation plays an active part in wound-healing. Teething in infants has an inflammatory component. Systemic inflammation is ubiquitous during and following parturition in mammals. There is inflammation everywhere, it's as generic a word as "oxidation" and "metabolism."

Every time you eat, the body enters a state of heightened inflammation. This is well documented. Please don't spread disinformation.

Two things:

First, if this is as well documented as you say then you should provide such documentation as you seem to think it should be at the finger tips of others.

Second, your comment doesn't actually counter the main point of what you are responding to. The point is that what "inflammation" means is too general. Even if it is true that you enter a "heightened inflammation" state when eating, that doesn't discredit the idea that inflammation as a category is being overloaded.

Re: Inflammation, but Not Telomere Length, Predicts Ageing at Extreme Old Age

#25

Post by darkteflon »

atat7024 wrote: post #16
legerdemain wrote: post #7

Earlier quoted context omitted.

Inflammation is a basic life process, not a reaction to the food you eat. Inflammation plays an active part in wound-healing. Teething in infants has an inflammatory component. Systemic inflammation is ubiquitous during and following parturition in mammals. There is inflammation everywhere, it's as generic a word as "oxidation" and "metabolism."

Every time you eat, the body enters a state of heightened inflammation. This is well documented. Please don't spread disinformation.

Pseudoscience schooling science.

Re: Inflammation, but Not Telomere Length, Predicts Ageing at Extreme Old Age

#26

Post by sparrc »

It's always strange to me how certain studies seem to gain so many upvotes on hackernews....a few thoughts:

1. This is a single study published in 2015, what does the wider literature say? Any dieticians or clinicians recommending anything from this?

2. The journal is EBioMedicine, which is not nothing but not exactly pre-eminent either.

3. This seems like just a common sense conclusion: "In Cox proportional hazard models, inflammation predicted all-cause mortality". So...people who die have inflammation? Wouldn't that be expected that people who are dieing are likely experiencing significant inflammation of at least one organ of their body?

4. In short, the conclusion of this paper seems like essentially "people who are dying are likely to die". Am I missing something here?

Re: Inflammation, but Not Telomere Length, Predicts Ageing at Extreme Old Age

#27

Post by pmiller2 »

derefr wrote: post #23

Anyone know how long mice live with all the genes for inflammatory responses knocked out?

Such an organism probably wouldn’t be compatible with life. Inflammation is necessary for healing wounds and immune response, among other things.

Re: Inflammation, but Not Telomere Length, Predicts Ageing at Extreme Old Age

#29

Post by cauliflower2718 »

treeman79 wrote: post #20
TimSchumann wrote: post #3

Anecdote, but this may explain why I feel so much healthier when I'm fasting regularly. Turns out, if you stop putting everything but water/salt in your body, there's not much left that causes inflammation.

Was in a massive Sjogrens flare. Stopped eating for a month. Collapsing aside, my inflammation was fixed. Did a month on sweet potatoes. Very boring but same result.

Why sweet potatoes?

Re: Inflammation, but Not Telomere Length, Predicts Ageing at Extreme Old Age

#30

Post by mkoubaa »

cauliflower2718 wrote: post #29
treeman79 wrote: post #20

Earlier quoted context omitted.

Was in a massive Sjogrens flare. Stopped eating for a month. Collapsing aside, my inflammation was fixed. Did a month on sweet potatoes. Very boring but same result.

Why sweet potatoes?

Yeah why not cauliflower
Post reply on HN