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Scientists grow bigger monkey brains using human genes, replicating evolution

interestingengineering.com

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Re: Scientists grow bigger monkey brains using human genes, replicating evolution

#21

Earlier quoted context omitted.

You'll never play Doom on a single NAND gate. Huge efforts in getting toasters, microwaves and pregnancy testers to run Doom notwithstanding.

But brains aren’t made of digital logic elements

You'll never play Doom on a single neuron.

Re: Scientists grow bigger monkey brains using human genes, replicating evolution

#22
This is crucial in order to maintain ethical boundaries. After about 100 days after the fetus had been growing, the international team unanimously agreed to remove the fetus through a C-section

I feel we’ve already entered into sensitive territory by aborting it.

Re: Scientists grow bigger monkey brains using human genes, replicating evolution

#25
post #2

This research is as terrific as it is terrifying. These are some terrific insights into the evolution of intelligence. I doubt that it was one gene alone that drove the whole thing, but as the article mentions, the ethical dilemmas already arise, and it's easy to see how scientifically valuable it would be to study the impact of the gene further by allowing the transgenic animals to be born. The ethical dilemmas cut…

Isn’t that literally the plot of the Planet of the Apes remake?

Maybe it is time for continental and east asian arms and self defence legislation to add an exception for putting down runaway lab experiments. Standing your ground and castle doctrines are privileges unique to America.

Re: Scientists grow bigger monkey brains using human genes, replicating evolution

#26

"To let them come to be born, in my opinion, would have been irresponsible as a first step," emphasis on the "as a first step"

It is an interesting ethical decision because it highlights a lot of assumptions about what is and is not ethical and moral. For example, take those that firmly believe abortion is murder. For them. then aborting this evolved fetus would be considered (to the extent that this applies to mutant non-human primates) the unethical thing to do, NOT the ethical thing to do. However, if you don't believe fetuses have inherent rights, etc, then the most ethical thing to do is to destroy the fetus before it does begin to reach that threshold where thorny ethical implications emerge.

Re: Scientists grow bigger monkey brains using human genes, replicating evolution

#29
From an engineering perspective, when trying to explore a dynamic, you simplify the experiment to reduce extraneous variables. So along these lines, I’d be more interested in following experiments like these on say sea slugs. Give them a proto-amygdala/hippocampus or limbic system and test them for increased memory, adaptive behavior etc. This choice of monkey experiment seems to be more sensation and less investigation, on the spectrum.

Re: Scientists grow bigger monkey brains using human genes, replicating evolution

#30
post #9

Earlier quoted context omitted.

Yea, I was talking to a fruit fly yesterday... Wait no, that’s not accurate because while larger brains don’t inherently equate to more intelligence, there is a minimum size for any given level of intelligence. That said, this wasn’t a test of intelligence, just how cells grow in response to specific genetic alterations.

I didn’t realize that was scientific consensus. So that would imply that brains under a certain size are incapable of higher levels of intelligence? I don’t think that’s right... I thought the consensus was that brain size has no strong correlation with intelligence at all. That makes sense considering how neurons work, the connections they form seem like they would be more causal.

Its a complicated question. Within the human species, the correlation is not that strong at all. In cross-species comparisons it tends to be quite strong, especially when considering brain to body weight ratios. Bird brains may be an interesting exception however, which I suspect can be quite intelligent, depending on how intelligence is measured.
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