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Old Dogs, New Research and the Secrets of Aging

nytimes.com

21–30 of 53 posts

Re: Old Dogs, New Research and the Secrets of Aging

#21
post #6

aging (and anti-aging medication) has the potential to become the next big thing. My dog is part if the DogAgingProject and it’s really exciting to see some focus on something that impacts all of us.

I have such mixed feelings about this.

It's not a great movie but this really does remind me of Elysium, in that we're truly heading for a world where those with means can live indefinitely. And those without means...

Re: Old Dogs, New Research and the Secrets of Aging

#22
From my grandparent to me, there has always been German Shepherds in our family. Starting the 80's all of our dogs started dying much earlier, ~6-7 of cancer. In the early 2000's, we switched to raw diet from premium store bought kibble to raw. Sure enough, not only did their coat improve not a single cancer death under age of 13. I know it's anecdotal, but in my dog world circle and family, we've all observed similar results.

It's a cruel that our best friends and most loyal companions live such short lives as it is. Giving them top nutrition is a small price for the added years.

As to how this applies to humans? If you want to live a long and healthy life: avoid processed foods.

Re: Old Dogs, New Research and the Secrets of Aging

#23

The best thing I learned from this article: to calculate a dog's human age, you don't multiply their age times 7 (7x). You use the following formula: ln(x)*16+31 It makes sense, because a 1-year-old dog definitely seems much more grown up than a 7 year old kid.

Umm...doesn't the formula imply that the dog age starts at 31?

That makes no sense either. My 1 year old dog is definitely not a 31 year old adult as far as behavior goes (incidentally, I am myself ~31,).

I'd put 1 year approximately equivalent to a teenager, depending on the size of the breed (12 year old for larger breeds, late teens for small breeds)

Re: Old Dogs, New Research and the Secrets of Aging

#24
post #15
post #5

Earlier quoted context omitted.

The site is almost 15 years old so it’s possible. People become a little more self-aware as they get older. First you know someone famous that died young from a horrible disease. Next you personally know someone who died from a disease. Then you get older and wonder if the “1 in 3 people” might be you.

I take anti-aging drugs for about 10 years. I heard about them at HN.

What's in your stack bruh?

Re: Old Dogs, New Research and the Secrets of Aging

#25
post #15
post #5

Earlier quoted context omitted.

The site is almost 15 years old so it’s possible. People become a little more self-aware as they get older. First you know someone famous that died young from a horrible disease. Next you personally know someone who died from a disease. Then you get older and wonder if the “1 in 3 people” might be you.

I take anti-aging drugs for about 10 years. I heard about them at HN.

Betting this is berberine or metformin?

Re: Old Dogs, New Research and the Secrets of Aging

#26
post #7
post #2

I've noticed more health and aging related articles on this site. I wonder if its a sign the HN community is getting older. :)

Could be that “pandemic” thing making people a bit more cognizant of mortality.

I think the increase of popularity of these types of articles happened mostly before the pandemic.

Re: Old Dogs, New Research and the Secrets of Aging

#27
post #20
post #2

I've noticed more health and aging related articles on this site. I wonder if its a sign the HN community is getting older. :)

I think a lot of it is that we're just now starting to get to where we need to be as a civilization for anti-aging to start to become something that not only sounds feasible, but is feasible. I've noticed interest steadily increasing over the last 5 or so years, and think this will be a huge topic in the next few decades.

The aging-related research has been going for quite some time, so it's not surprising it's starting to bear fruit, for now in the form of better understanding of the underlying mechanisms. The consensus seems to be shifting from "wear-and-tear model" to a series pre-programmed epigenetic alterations, which, to me at least as a layman, feels more plausible. There's a good chance we'll see some anti-aging treatments released within our lifetimes. We might end up being the first generation to have reached the longevity escape velocity.

The reason it's only starting to emerge now is as far as I understand that molecular biology is a relatively new field, and the related technologies simply didn't exist not so long ago.

Re: Old Dogs, New Research and the Secrets of Aging

#28
post #22

From my grandparent to me, there has always been German Shepherds in our family. Starting the 80's all of our dogs started dying much earlier, ~6-7 of cancer. In the early 2000's, we switched to raw diet from premium store bought kibble to raw. Sure enough, not only did their coat improve not a single cancer death under age of 13. I know it's anecdotal, but in my dog world circle and family, we've all observed simila…

Counterpoint: My dog survived distemper as a puppy and had life-long digestive issues. I tried all sorts of elimination diets, raw foods, probiotics, etc. Nothing worked. I finally put him on a Rx dog food from purina with high fiber and a bunch of the 'garbage' ingredients I spent years trying to avoid. His digestive issues disappeared and he had some of the best years of his life. He died close to 17 years old, which isn't bad for a 42 pound dog.

Re: Old Dogs, New Research and the Secrets of Aging

#29

The best thing I learned from this article: to calculate a dog's human age, you don't multiply their age times 7 (7x). You use the following formula: ln(x)*16+31 It makes sense, because a 1-year-old dog definitely seems much more grown up than a 7 year old kid.

I think you need to take the dog's weight and breed into account. Something like: https://www.akc.org/expert-advice/health/how-to-calculate-do....

Re: Old Dogs, New Research and the Secrets of Aging

#30

Earlier quoted context omitted.

Anecdotally I'm assuming this equation must be breed-specific because I've had a number of dogs 8+ years old that did not appear to act or look very senior.

Playing around with the numbers a bit, I think it's pretty seriously wrong. A 6-month old dog is still a child, in dog terms. This formula says they're nearly 20 years old; I'd be inclined to say that the "right" answer is more like 15 years, if not less. A 1-year old dog is beyond adolescence but is still maturing, but this formula says they're 31 years old, well into adulthood. A 5-year old dog is in the prime of t…

Actually I think I agree with your assessment more. None of the age alignments really make a whole lot of sense to me, even for bigger breeds of dogs. Also, I feel like I've noticed adolescent and mischevious behavior in some of our dogs well into the 2-3 age range on occasion

This behavior mainly noted for cocker spaniels and Korean jindos

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